Navigation Links
Melanoma lurks in larger skin lesions, NYU researchers find
Date:4/22/2008

Skin lesions that are about the size of a pencil eraser are more likely to be melanomas, a deadly form of skin cancer, than smaller moles, according to a new study led by NYU Langone Medical Center researchers.

In a new study published in the April issue of Archives of Dermatology, the NYU researchers confirm that an important warning sign of melanoma moles that are larger than 6 millimeters, the size of a pencil eraser is still valid. In recent years, some researchers have argued that strict adherence to this guideline may make clinicians miss smaller melanomas.

Diameter is a reasonable guideline to pay attention to and we did not see any reason to change it, says David Polsky, M.D., Ph.D., assistant professor of dermatology and associate director of the Pigmented Lesions Section in the Roland O. Perelman Department of Dermatology at NYU School of Medicine, who led the study.

Lesions that are smaller than 6 millimeters are unlikely to be melanoma. New and changing lesions are the most concerning, and lesions that are multiple colors are especially suspicious, says Dr. Polsky.

More than 20 years ago, NYU dermatologists developed a widely used rule, the ABCD acronym, for recognizing growths on the skin that could be early melanomas. They recently added the letter E to the list. The warning signs are: A for asymmetrical lesions; B, lesions with irregular borders; C, lesions with multiple colors; D, for lesions larger than 6 millimeters; and E for evolving lesions that change in size, color, shape or symptoms such as itching over time.

The incidence of melanoma continues to rise. The American Cancer Society estimates that in 2008 there will be 62,480 new cases of melanoma in the United States. About 8,420 people will die of this disease this year. Excessive exposure to sunlight, a fair complexion, a family history of melanoma, and numerous moles, among other factors, place people at higher risk for the disease.

In the new study, Dr. Polsky and his colleagues used a computerized imaging system to measure the lesions in a large database of melanoma cases. They evaluated the lesions of 1,323 patients undergoing biopsies of 1,657 suspicious pigmented lesions. Based on their analysis, 804 or 48.5 percent of the lesions were larger than 6 millimeters in diameter and 138 or 8.3 percent were diagnosed as melanoma. Invasive melanoma, which has penetrated deeper into the skin and is most life threatening, was diagnosed in only 13 or 1.5 percent of 853 lesions that were 6 millimeters or smaller in diameter. By contrast, the invasive type was diagnosed in 41 or 5.1 percent of 804 lesions larger than 6 millimeters.

In situ melanomas, which are less dangerous because they remain in the skins outer layers, were diagnosed in 22 or 2.6 percent of 853 lesions 6 millimeters or smaller in diameter and in 62 or 7.7 percent of 804 lesions larger than 6 millimeters.


'/>"/>

Contact: Jennifer Berman
Jennifer.Berman@nyumc.org
212-404-3555
New York University Medical Center and School of Medicine
Source:Eurekalert

Related medicine news :

1. Larger Skin Lesions More Likely to Be Melanoma
2. Most lethal melanomas are on scalp and neck
3. Survival rates appear lower for scalp and neck melanoma than for other sites
4. Larger skin lesions appear more likely to be melanomas
5. Melanomas on Scalp and Neck More Deadly
6. Gleevec Pushes Advanced Melanoma Into Remission
7. Interleukin-12 indicates survival prospects for melanoma patients
8. Drug Proves Effective in Slowing Melanomas
9. Indoor Tanning Association Launches Campaign Attacking Melanoma Hype
10. DermTech Adds Allan C. Halpern, MD, Chief of Dermatology at Memorial Sloan- Kettering Cancer Center, to Companys Melanoma Advisory Board
11. Embryonic Stem Cell Protein Inhibits Melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/7/2016)... ... February 07, 2016 , ... ... empowers employers and organizations with the tools and information to lower the costs, ... to cut the cost of providing employee healthcare benefits by as much as ...
(Date:2/6/2016)... ... February 06, 2016 , ... US Sports Camps is proud to sponsor ... event brings together top non-profit leaders, ultimate organizations, and coaches from around the US. ... Bay Area Disc Program Director of Youth and Education, describes this year YUCC as ...
(Date:2/6/2016)... Pekin, IL (PRWEB) , ... February 06, 2016 ... ... the recovery phases of eating disorder treatment helps to reduce the frequency and ... “Tasks of the Recovery Phase: Re-Establishing Healthy Identity and Purpose,” will explore the ...
(Date:2/5/2016)... ... February 05, 2016 , ... VeloReality ... lighter, sleeker next generation LYNX VR Indoor Trainer with multi-rider capability to an ... and manufacturing not only reduce the weight of the unit, they also enhance ...
(Date:2/5/2016)... ... 2016 , ... The event is being held on April 7, 2016 from ... Triumph Over Parkinson’s will fund nearly $100,000 for research for the care and cure ... disease and is the architect of this informative event to raise awareness and funds ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016 Aethlon Medical, Inc. (Nasdaq: AEMD ), ... will be presenting at Source Capital Group,s 2016 Disruptive Growth ... at 2:15 p.m. ET on Wednesday, February 10, 2016.  ... taking place at 3:15 p.m. ET. http://www.aethlonmedical.com .  ... after the conclusion of the live event. The panel discussion ...
(Date:2/5/2016)... , February 5, 2016 ... market research report "Fetal (Labor & Delivery) and Neonatal ... Warmer, Incubator, Pulse Oximeter, Phototherapy/Jaundice Management Devices, CPAP, Capnograph, ... MarketsandMarkets, This report studies the global market over the ... estimated at USD 6.28 Billion in 2015 and is ...
(Date:2/4/2016)... Feb. 4, 2016 For hospitals considering enrollment ... already participating in the program, the Health Resources and ... as the , Mega-Guidance , could have significant impact ... published in September 2016. Essential Insights , ... Marketing , summarizes the Mega-Guidance,s key proposed changes, including ...
Breaking Medicine Technology: