Navigation Links
Melanoma Vaccine Shows Promise in Trial
Date:6/1/2011

By Jenifer Goodwin
HealthDay Reporter

WEDNESDAY, June 1 (HealthDay News) -- For patients with advanced melanoma, the most dangerous type of skin cancer, a vaccine combined with an immune-boosting drug is showing promise in a large clinical trial.

Therapeutic cancer vaccines, unlike typical vaccines that prevent infections, are meant to jump-start the immune system to help it battle existing tumors.

In this Phase 3 clinical trial, conducted at 21 care centers, researchers randomly assigned 185 patients with metastatic melanoma, meaning the cancer had spread, to either the vaccine followed by interleukin-2, a drug that activates the immune system, or interleukin-2 alone.

Those given the vaccine-drug combo showed more improvement than those given the drug alone, according to the study, which was published in the June 2 issue of the New England Journal of Medicine.

About 16 percent of those given the vaccine/interleukin-2 combination saw their tumors shrink by 50 percent or more, compared to 6 percent given interleukin-2 alone.

Those in the vaccine/drug group also had slightly longer "progression-free" survival -- 2.2 months compared to 1.6 months -- meaning they had more time in which the tumor didn't grow.

Patients given the combo also lived an average of nearly 7 months longer than those only give interleukin-2 -- nearly 18 months compared to about 11 months. While a "strong trend," those results were not statistically significant, said lead study author Dr. Douglas Schwartzentruber, medical director of the Goshen Center for Cancer Care at Indiana University Health.

"This is the first time that a vaccine has shown benefit in the treatment of patients with metastatic melanoma, and it's an early example of success with a cancer vaccine," Schwartzentruber said.

He and the other researchers reported that although the treatment-related toxic effects were similar in both groups,
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Penn study identifies genes that may help predict response to BRAF inhibitors for advanced melanoma
2. Shave biopsy is a safe and acceptable method for initial evaluation of melanoma
3. New technique extends cancer-fighting cells potency in melanoma patients
4. Topical treatment may prevent melanoma
5. Scientists Spot Key Gene Mutations in Melanoma
6. Blood Test May Help Predict Spread of Melanoma
7. Blood test could predict metastasis risk in melanoma
8. Researchers use zebrafish to identify new gene linked to melanoma
9. Researchers publish molecular disease model for melanoma
10. FDA approves new drug for advanced melanoma
11. FDA approves ipilimumab, an immunotherapy, to treat metastatic melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Melanoma Vaccine Shows Promise in Trial 
(Date:6/29/2015)... ... June 29, 2015 , ... National HealthCare Associates recently ... service for the 40-center nursing home group. Sixteen of their centers were rated ... United States in one or more customer service areas. Those centers received the ...
(Date:6/29/2015)... (PRWEB) , ... June 29, 2015 , ... ... have developed a new approach to build nearly complete genomes by combining high-throughput ... of genomic variation, critically important for their association with human disease, but previously ...
(Date:6/29/2015)... ... June 29, 2015 , ... With Urgent Care Medicine now serving a vital ... Board of Urgent Care Medicine and the Medical Society of Delaware to provide its ... physicians and health care professionals. , According to Matthew Bader, Exam Master CEO and ...
(Date:6/29/2015)... ... June 29, 2015 , ... USA Today reported on ... Dakota, Arkansas, and Alabama. To impact the rest of the nation’s growing overdose death ... suggested the following guidelines be followed to stop the increasing overdose trend from continuing: ...
(Date:6/29/2015)... ... June 29, 2015 , ... OR Manager announced Monday ... look and feel, as well as a redesigned logo and weekly eLetter. The website ... is now more user-friendly and easier to navigate. , In addition to a ...
Breaking Medicine News(10 mins):Health News:National HealthCare Centers Receive 'Customer Experience Awards' 2Health News:National HealthCare Centers Receive 'Customer Experience Awards' 3Health News:National HealthCare Centers Receive 'Customer Experience Awards' 4Health News:Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation 2Health News:Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation 3Health News:Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation 4Health News:Exam Master Partners to Provide New Urgent Care Continuing Medical Education Resource 2Health News:Exam Master Partners to Provide New Urgent Care Continuing Medical Education Resource 3Health News:Overdose Death Rates Decreased in Florida as of 2015 2Health News:Overdose Death Rates Decreased in Florida as of 2015 3Health News:OR Manager Launches New Website 2
... aerated beverages, yoga exponent Ramdev today asked the Centre ... that a statutory warning be written on every bottle ... a statutory warning should be written on every bottle ... infertility and diabetes,' he told reporters here., ,He ...
... Composite Laboratory at Kandaghat has not been functioning for over a ... since the former official for drug analyzing retired a month ago, ... his place. The number of samples awaiting testing at the laboratory ... Wasuja retired on April 30 after 38 years of service. With ...
... Goa, has suggested that the phar produce medicines which ... // He made this suggestion after inaugurating the new ... days ago. ,He also added that modern medicines and ... it was, therefore, essential that in the field of health ...
... High Court today held that medical colleges should give ... got caste validity certificate despite applying for the same. ... submit the certificate within 90 days of the admission, ... quotas, a candidate has to provide a caste certificate ...
... Australia could be receiving food supplements to improve their behaviour ... it is still investigating the feasibility of doing so. ... Department would review the British study, which claimed that children ... of Omega 3 fish oil. ,"The focus in ...
... Ramadoss Wednesday assured representatives of the civil society ... bring amendments in the legislation concerned to prevent ... willing to bring further amendments in the Preconception ... Act for stricter enforcement of the legislation," Ramadoss ...
Cached Medicine News:Health News:Working of Drug Department on Hold Without Drug Analyst 2
(Date:6/29/2015)... June 29, 2015 According to a ... Microwave, Cryoablation, IRE, Ultrasound), Mode of treatment (Surgical, Laparoscopic, Percutaneous), ... Forecasts to 2020", published by MarketsandMarkets, the global Tumor Ablation ... at a CAGR of 11.5% from 2015 to 2020. ... 86 F igures spread through 330 ...
(Date:6/29/2015)... Md. , June 29, 2015 The ... New Jersey Board of Professional ... a provider of courses to professional engineers for continuing ... accreditation further demonstrates the value and quality of PDA,s ... . "Our lecture courses and hands-on professional training at ...
(Date:6/29/2015)... 29, 2015  VisionCare Ophthalmic Technologies, Inc. ... devices for the treatment of age-related macular ... "Long-Term (60-month) Results for the Implantable Miniature ... Age in Patients with End-Stage Age-Related Macular ... 5-year data show substantial retention of gains ...
Breaking Medicine Technology:Tumor Ablation Market Worth $515.2 Million by 2020 2Tumor Ablation Market Worth $515.2 Million by 2020 3Tumor Ablation Market Worth $515.2 Million by 2020 4Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 2Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 3Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 4Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 5
... Dec. 21, 2011  In a move aimed at bolstering current ... Hospital Boston have created a new method that combines multiple ... Unlike current approaches, which rely on detecting evidence of drug ... this new method may be able to identify issues years ...
... 2011 Despite the numerous medical advances that happen ... States is still higher than most European countries.  While ... rate of pre-term births, researchers are committed to finding ... Medicine ® researchers are examining a new ...
Cached Medicine Technology:Taking a Predictive Approach to Identifying Adverse Drug Reactions 2Taking a Predictive Approach to Identifying Adverse Drug Reactions 3Northwestern Researchers Trial New Device that May Support Improved Newborn Health 2Northwestern Researchers Trial New Device that May Support Improved Newborn Health 3Northwestern Researchers Trial New Device that May Support Improved Newborn Health 4
... by seeing more patients per day. Utilizing the ... a 14-18 patients per day practice into a ... test sequences, youll perform accurate refractions in less ... making it easy to delegate tasks to office ...
... web-based application for secure access to ... reporting system. It is highly user ... comprehensive analysis, and professional reporting from ... with HIPAA requirements, reports also include ...
... Nothing can be more frustrating to a ... section of tissue than using instruments that are ... simple, or more complex, we offer a wide ... From realigning and polishing the tips to standard ...
... We repair most Olympus fiber and ... and intubation scopes used in OR and ... all repairs meet or exceed the standards ... with a 120-day warranty against defects in ...
Medicine Products: