Navigation Links
Melanoma May Be More Aggressive in Kids
Date:10/7/2011

FRIDAY, Oct. 7 (HealthDay News) -- Some children with melanoma are more likely to have invasive disease than adults with this potentially deadly type of skin cancer, a new study indicates.

The findings suggest that there may be biological differences between childhood and adult melanoma, said the researchers at the Johns Hopkins Children's Center in Baltimore.

They analyzed the medical records of 717 children and 1,368 young adults (aged 20 to 24) diagnosed with melanoma and compared sentinel lymph node biopsy results based on tumor size, tumor appearance and patient age. Sentinel lymph nodes are those that surround the tumor, and sentinel lymph node biopsy is the standard way to assess spread (metastasis) of the cancer and determine treatment.

Cancer cells were found in the sentinel lymph nodes of 25 percent of children and 14 percent of adults who had biopsies. Tumor thickness was the strongest predictor of lymph node metastases in both children and adults.

But children with tumors with a thickness of 1.01 and 2 millimeters were nearly six times more likely than young adults with same-thickness tumors to have cancer cells in sentinel lymph nodes.

The researchers also found that children younger than 10 were more likely to have distant metastases (spread of cancer beyond the immediate tumor site) and greater tumor thickness, compared with older children and young adults.

Regardless of age, patients with bleeding tumors or those with open sores were more likely to have metastases.

The study was published online Oct. 5 in the journal Cancer.

"Our finding is a powerful reminder that there's much about pediatric melanoma that we don't understand and that, just as is the case with other diseases, children are not small adults, but differ markedly in their response to disease," senior investigator Dr. John Strouse, a pediatric hematologist and oncologist, said in a Johns Hopkins Medicine news release.

Although still uncommon, melanoma diagnoses in children are increasing, and unprotected sun exposure, sunburns and indoor tanning are some of the known causes.

More information

The American Academy of Family Physicians has more about melanoma.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, Oct. 5, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scanning for skin cancer: Infrared system looks for deadly melanoma
2. Non-Melanoma Skin Cancers in the Millions and Rising
3. Late-stage melanoma results in economic burden
4. Clinical trial to test whether vaccine can effectively treat melanoma
5. Wistar scientists explain the persistence of melanoma through dynamic stemness
6. Tanning Beds Can Greatly Boost Melanoma Risk
7. U of M study definitively links indoor tanning to melanoma
8. Indoor Tanning Beds Increase Risk of Melanoma
9. Novel Drug Combats Advanced Melanoma
10. Combination treatment regimen not effective against advanced melanoma
11. New treatment method safe, effective for advanced melanoma patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Melanoma May Be More Aggressive in Kids
(Date:10/13/2017)... Calif. (PRWEB) , ... October 13, 2017 , ... Many ... dementia. However, many long-term care insurance companies have a waiver for care if the ... 90-day elimination period, when the family pays for care, is often waived, so the ...
(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... services for healthcare compliance program management, will showcase a range of technology and ... for Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... ORANGE COUNTY, Calif. , Oct. 10, 2017  NDS received ... Mobile  — a medical-grade battery-powered display stand specifically designed for ... aims to transform technology into a clinical solution to support the ... costs. Innovative Design ... NDS ZeroWire Mobile Wireless Solution ...
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... , Oct. 2, 2017 Halo Labs announces the European ... system called the HORIZON at MIBio 2017 in Cambridge, ... and visible particulate matter in biopharmaceutical samples with unprecedented speed and ... the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: