Navigation Links
Melanoma May Be More Aggressive in Kids
Date:10/7/2011

FRIDAY, Oct. 7 (HealthDay News) -- Some children with melanoma are more likely to have invasive disease than adults with this potentially deadly type of skin cancer, a new study indicates.

The findings suggest that there may be biological differences between childhood and adult melanoma, said the researchers at the Johns Hopkins Children's Center in Baltimore.

They analyzed the medical records of 717 children and 1,368 young adults (aged 20 to 24) diagnosed with melanoma and compared sentinel lymph node biopsy results based on tumor size, tumor appearance and patient age. Sentinel lymph nodes are those that surround the tumor, and sentinel lymph node biopsy is the standard way to assess spread (metastasis) of the cancer and determine treatment.

Cancer cells were found in the sentinel lymph nodes of 25 percent of children and 14 percent of adults who had biopsies. Tumor thickness was the strongest predictor of lymph node metastases in both children and adults.

But children with tumors with a thickness of 1.01 and 2 millimeters were nearly six times more likely than young adults with same-thickness tumors to have cancer cells in sentinel lymph nodes.

The researchers also found that children younger than 10 were more likely to have distant metastases (spread of cancer beyond the immediate tumor site) and greater tumor thickness, compared with older children and young adults.

Regardless of age, patients with bleeding tumors or those with open sores were more likely to have metastases.

The study was published online Oct. 5 in the journal Cancer.

"Our finding is a powerful reminder that there's much about pediatric melanoma that we don't understand and that, just as is the case with other diseases, children are not small adults, but differ markedly in their response to disease," senior investigator Dr. John Strouse, a pediatric hematologist and oncologist, said in a Johns Hopkins Medicine news release.

Although still uncommon, melanoma diagnoses in children are increasing, and unprotected sun exposure, sunburns and indoor tanning are some of the known causes.

More information

The American Academy of Family Physicians has more about melanoma.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, Oct. 5, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scanning for skin cancer: Infrared system looks for deadly melanoma
2. Non-Melanoma Skin Cancers in the Millions and Rising
3. Late-stage melanoma results in economic burden
4. Clinical trial to test whether vaccine can effectively treat melanoma
5. Wistar scientists explain the persistence of melanoma through dynamic stemness
6. Tanning Beds Can Greatly Boost Melanoma Risk
7. U of M study definitively links indoor tanning to melanoma
8. Indoor Tanning Beds Increase Risk of Melanoma
9. Novel Drug Combats Advanced Melanoma
10. Combination treatment regimen not effective against advanced melanoma
11. New treatment method safe, effective for advanced melanoma patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Melanoma May Be More Aggressive in Kids
(Date:8/16/2017)... ... August 16, 2017 , ... ... through affiliations and de novo development, today announced Cumberland Skin Surgery and ... Skin Surgery and Dermatology, with offices in both Hermitage and Lebanon, Tennessee, provides ...
(Date:8/16/2017)... ... ... LabRoots , the leading provider of educational and interactive virtual events ... Andrew Ly as the winner of the LabRoots Summer Textbook scholarship, awarding him $1000 ... is in his third year at the University of California, Los Angeles majoring in ...
(Date:8/16/2017)... (PRWEB) , ... August 16, 2017 , ... Fusion Flix ... premium original programming over four countries and millions of viewers in a partnership with ... rent or buy On-Demand and fully available on Blu Ray disc in 2018. Proceeds ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... new client win in the healthcare market, with Los Angeles-based AIDS Healthcare Foundation ... staff and members. , AHF cares for nearly 800,000 individuals worldwide and is ...
(Date:8/16/2017)... ... 2017 , ... Rollon Skin Care Ltd., one ... announced the launch of two new skincare products, Prache Antiaging Cream and Prache ... plastic surgery or in-patient cosmetic dermatological procedures. , “Prache Antiaging Cream and Prache ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... , Aug. 2, 2017 CaryRx, a next-generation ... day delivery service for patients in the Washington ... traditional retail pharmacy by providing delivery of medications through the ... for future delivery or delivered within one hour to any ... are excited to bring this invaluable service to ...
(Date:7/31/2017)... 7D Surgical, developer of ground breaking surgical navigation ... Surgical System to support its strategic sales plan in ... and Virginia.  7D Surgical has entered into an exclusive sales ... medical facilities within those markets. ... Spartan Medical Purchases ...
(Date:7/27/2017)... 2017  West Pharmaceutical Services, Inc. (NYSE: ... second-quarter 2017 and updated financial guidance for the full-year ... Highlights Reported net sales of $397.6 ... quarter. Net sales at constant currency (organic) grew by ... $0.51, compared to $0.60 in the prior-year quarter. Second-quarter ...
Breaking Medicine Technology: