Navigation Links
Melanoma May Be More Aggressive in Kids
Date:10/7/2011

FRIDAY, Oct. 7 (HealthDay News) -- Some children with melanoma are more likely to have invasive disease than adults with this potentially deadly type of skin cancer, a new study indicates.

The findings suggest that there may be biological differences between childhood and adult melanoma, said the researchers at the Johns Hopkins Children's Center in Baltimore.

They analyzed the medical records of 717 children and 1,368 young adults (aged 20 to 24) diagnosed with melanoma and compared sentinel lymph node biopsy results based on tumor size, tumor appearance and patient age. Sentinel lymph nodes are those that surround the tumor, and sentinel lymph node biopsy is the standard way to assess spread (metastasis) of the cancer and determine treatment.

Cancer cells were found in the sentinel lymph nodes of 25 percent of children and 14 percent of adults who had biopsies. Tumor thickness was the strongest predictor of lymph node metastases in both children and adults.

But children with tumors with a thickness of 1.01 and 2 millimeters were nearly six times more likely than young adults with same-thickness tumors to have cancer cells in sentinel lymph nodes.

The researchers also found that children younger than 10 were more likely to have distant metastases (spread of cancer beyond the immediate tumor site) and greater tumor thickness, compared with older children and young adults.

Regardless of age, patients with bleeding tumors or those with open sores were more likely to have metastases.

The study was published online Oct. 5 in the journal Cancer.

"Our finding is a powerful reminder that there's much about pediatric melanoma that we don't understand and that, just as is the case with other diseases, children are not small adults, but differ markedly in their response to disease," senior investigator Dr. John Strouse, a pediatric hematologist and oncologist, said in a Johns Hopkins Medicine news release.

Although still uncommon, melanoma diagnoses in children are increasing, and unprotected sun exposure, sunburns and indoor tanning are some of the known causes.

More information

The American Academy of Family Physicians has more about melanoma.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, Oct. 5, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scanning for skin cancer: Infrared system looks for deadly melanoma
2. Non-Melanoma Skin Cancers in the Millions and Rising
3. Late-stage melanoma results in economic burden
4. Clinical trial to test whether vaccine can effectively treat melanoma
5. Wistar scientists explain the persistence of melanoma through dynamic stemness
6. Tanning Beds Can Greatly Boost Melanoma Risk
7. U of M study definitively links indoor tanning to melanoma
8. Indoor Tanning Beds Increase Risk of Melanoma
9. Novel Drug Combats Advanced Melanoma
10. Combination treatment regimen not effective against advanced melanoma
11. New treatment method safe, effective for advanced melanoma patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Melanoma May Be More Aggressive in Kids
(Date:2/12/2016)... , ... February 12, 2016 , ... Yisrayl Hawkins, Pastor ... article this week that uncovers what he says are the real facts surrounding all ... the Bible from parents and Sunday school teachers, and Yisrayl says there is more ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... Dignity Health ... General Hospital Emergency Room –Mesa. The new facility is licensed under Dignity ... , “Dr. Bingham is an excellent leader and will ensure our new freestanding emergency ...
(Date:2/11/2016)... ... 11, 2016 , ... SPH Analytics announced today that ... health solutions, MDinsight® and IndiGO®, for its primary care clinicians. The 3-year partnership ... the contract were not disclosed. , As the healthcare market moves towards quality-based ...
(Date:2/11/2016)... Tampa, FL (PRWEB) , ... February 11, 2016 , ... ... Tampa Bay Lightning take on the St. Louis Blues at the Amalie Arena. The ... only portable, inflatable, walk-through heart exhibit, the MEGA Heart, prior to the game. The ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... ranked among the top five firms in the “2015/2016 Best in KLAS: Software ... and Staffing. KLAS is a research and insights firm on a global mission ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... February 11, 2016 Jeffrey Zucker ... Clinical Trials, will present at this year,s Summit for Clinical ... Regency in Miami, FL. Zucker will ... optimize study execution, supporting SCOPE,s "Improving Site Study Activation and ... on Thursday, Feb. 25 at 11:05 a.m. ...
(Date:2/11/2016)... 2016  Community pharmacists can help improve medication adherence ... through a custom-built medication synchronization program, Cardinal Health MedSync ... at Schieber Family Pharmacy in ... of patients enrolled in this medication synchronization program, which ... for the patient, and it,s a win for us ...
(Date:2/11/2016)... , Feb. 11, 2016  M3 Biotechnology Inc., spurred by a major "team investment" by ... brother, Michael, has completed an oversubscribed Series A-Round, according to CEO Leen Kawas , PhD. ... ... ... ...
Breaking Medicine Technology: