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Medicine's Future Could Lie in Each Patient's Genome
Date:3/11/2010

But, for many patients, an accurate diagnosis will at least be a move in the right direction.

"If you were the parent of a child with a disorder and you had taken your child to doctor after doctor after doctor and were given either no diagnosis or a vague diagnosis, to even have a clear-cut diagnosis that doesn't come with an intervention, that's a huge step forward and a great relief," Finnell said.

In the meantime, traditional genome-wide association studies, which compared the genomes of people who had a disease with people who didn't have the disease, are going to be "left in the dust," Marion said.

More information

Learn more about genetics at the Human Genome Project.



SOURCES: Robert Marion, M.D., chief of genetics and development medicine and director, Center for Congenital Disorders, Children's Hospital at Montefiore Medical Center, New York City, and author, Genetic Rounds: A Doctor's Encounters in the Field That Revolutionized Medicine; Jeffery Vance, M.D., Ph.D., director, Center for Genomic Medicine, Hussman Institute for Human Genomics, University of Miami Miller School of Medicine; Richard H. Finnell, Ph.D., professor of environmental and genetic medicine, Texas A&M Health Science Center Institute of Biosciences and Technology, Houston; March 11, 2010, Science; New England Journal of Medicine


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