Navigation Links
Medications found to cause long term cognitive impairment of aging brain
Date:7/13/2010

INDIANAPOLIS Drugs commonly taken for a variety of common medical conditions including insomnia, allergies, or incontinence negatively affect the brain causing long term cognitive impairment in older African-Americans, according to a study appearing in the July 13, 2010 print issue of Neurology, the medical journal of the American Academy of Neurology.

These drugs, called anticholinergics, block acetylcholine, a nervous system neurotransmitter, and are widely-used medical therapies. They are sold over the counter under various brand names such as Benadryl, Dramamine, Excedrin PM, Nytol, Sominex, Tylenol PM, and Unisom. Other anticholinergic drugs, such as Paxil, Detrol, Demerol and Elavil are available only by prescription. Older adults most commonly use drugs with anticholinergic effects as sleep aids and to relieve bladder leakage problems.

Researchers from Indiana University School of Medicine, the Regenstrief Institute and Wishard Health Services conducted a six-year observational study, evaluating 1,652 Indianapolis area African-Americans over the age of 70 who had normal cognitive function when the study began. In addition to monitoring cognition, the investigators tracked all over-the-counter and prescription medications taken by study participants.

"We found that taking one anticholinergic significantly increased an individual's risk of developing mild cognitive impairment and taking two of these drugs doubled this risk. This is very significant in a population African-Americans already known to be at high risk for developing cognitive impairment," said Noll Campbell, PharmD, first author of the study. Dr. Campbell is a clinical pharmacist with Wishard Health Services.

"Simply put, we have confirmed that anticholinergics, something as seemingly benign as a medication for inability to get a good night's sleep or for motion sickness, can cause or worsen cognitive impairment, specifically long-term mild cogni
'/>"/>

Contact: Cindy Fox Aisen
caisen@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Psychotropic medications can cause birth defects
2. Publix Pharmacy Now Offers Pill Glide, an Innovative New Way for Children and Adults to Take Vitamins, Supplements and Medications
3. HIRC Research Alert: Health Plans Expected to Increase Adoption of Percent Copays to Manage Specialty Medications
4. Oralflo Pill Swallowing Cup Wins Medical Design Excellence Award, Helps Autism Spectrum Kids and Dysphagia Sufferers Take Medications With No Problem
5. Study cautions: Psychotropic medications overprescribed to children
6. Adverse drug effects in epileptic patients not correlated with number of prescribed medications
7. Pollen.com Reports Five U.S. Cities with Highest Pollen Activity -- Total Prescriptions for Allergy Medications 3.7% Higher than Last Year
8. New England Journal of Medicine Article Trumpets “Priority” Status of Helping Patients Take Medications Correctly
9. South Dakota Students with Asthma Can Breathe Easier After New Law Allows Self-Administered Medications
10. Certain pain medications do not appear to be associated with skin cancer risk
11. The Kristen Renee Foundation Continues to Fight for Frederick, MD for Answers from the EPA and Fort Deterick
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Medications found to cause long term cognitive impairment of aging brain
(Date:1/22/2015)... Yesterday, Senator Holly Mitchell (D-Los ... Olsen (R-Modesto) were honored by the California Healthcare ... biomedical science, medical device and pharmaceutical innovation in ... “2014 Life Sciences Champion” award from CHI President ...
(Date:1/22/2015)... January 22, 2015 Four years since the release ... which coincided with the marriage of Avasa & Matthew Love – ... which is scheduled for release through White Swan Records on February ... there is a sacred path available to all of us to ...
(Date:1/22/2015)... As interest in the value of spiritual support ... Rev. Eric J. Hall , president and CEO of ... be the keynote speaker on January 27 at an international ... , The conference, “Hope and Resilience: Innovative and Interdisciplinary Spiritual ...
(Date:1/22/2015)... has released a new blog post explaining the importance of keeping ... costs of an auto insurance policy . , Clients who ... for their vehicle insurance policies. The safety a vehicle offers from ... Because of this, drivers should always carry a first aid kit ...
(Date:12/26/2014)... (PRWEB) December 26, 2014 The US represents ... this report. In 2013, GlobalData’s forecast estimates that sales of ... CRC market due to the high incidence of the disease, ... the 5EU, Japan, and China. Increased sales of CRC therapies ...
Breaking Medicine News(10 mins):Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 2Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 3Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 4
... , TUESDAY, July 5 (HealthDay News) -- Youngsters who aren,t ... behavioral or emotional problems as a result, suggests new research. ... other developmental delays, may exhibit some mild behavioral issues or ... problems don,t persist after the youngsters, language skills catch up. ...
... 5 (HealthDay News) -- Children with a parent on long-term ... for mental health problems, new research suggests. In the ... Archives of Pediatrics and Adolescent Medicine , researchers examined ... 17, who had at least one parent on active duty ...
... 9.6% of lung cancer patients tested in the Lung ... reflecting how many patients might benefit from targeted therapies ... 14th World Conference on Lung Cancer in Amsterdam, hosted ... Cancer (IASLC). ,The Lung Cancer Mutation Consortium (LCMC), ...
... may identify lung cancers that respond best to tyrosine ... for personalized therapy, according to research presented at the ... by the International Association for the Study of Lung ... are becoming available for non-small cell lung cancer therapy, ...
... -- Cuddling and caressing are important ingredients for long-term ... at relationship and sexual satisfaction throughout committed relationships, but ... men than to the women. Also contrary ... to report being happy in their relationship, while women ...
... two to three times more likely to develop a life-threatening blood ... published on bmj.com today. The new study ... risk of developing a pulmonary embolism a common cause of ... that, although the risk is small equivalent to seven extra ...
Cached Medicine News:Health News:Tots Who Are 'Late Talkers' Typically Turn Out Fine: Study 2Health News:Tots Who Are 'Late Talkers' Typically Turn Out Fine: Study 3Health News:Parents' Military Deployment May Harm Kids' Mental Health 2Health News:ALK rearrangement found in nearly 10 percent of patients in Lung Cancer Mutation Consortium 2Health News:PET scan with [11C]erlotinib may provide noninvasive method to identify TKI-responsive lung tumors 2Health News:Couples report gender differences in relationship, sexual satisfaction over time 2Health News:Couples report gender differences in relationship, sexual satisfaction over time 3Health News:Sitting for long periods doubles risk of blood clots in the lungs 2
(Date:1/23/2015)... a third of reproductive-aged women enrolled in Medicaid, and more ... prescription for an opioid pain medication each year during 2008-2012, ... Weekly Report (MMWR). Opioids are typically prescribed ... They are also found in some prescription cough medications. The ...
(Date:1/23/2015)... YORK , Jan. 23, 2015 /PRNewswire/-- Harwood Feffer LLP ... board of directors of Advaxis, Inc. ("Advaxis" or the ... board has breached its fiduciary duties to shareholders. ... on an investing website reporting that Advaxis had misrepresented ...
(Date:1/23/2015)... 23, 2015  HyGreen, Inc., a leader in hand hygiene ... RCA Medical, a subsidiary of Ascendis Health Limited, in ... Each year, hundreds of millions of patients around the ... are transmitted from patient to patient via the unwashed ...
Breaking Medicine Technology:Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2HyGreen Partners with RCA Medical in Johannesburg, South Africa 2
... overwhelming number of children with eye and vision problems ... appointments to no-cost, comprehensive eye and vision assessments for ... InfantSEE®. InfantSEE®, a public health program ... Vistakon®, Johnson & Johnson Vision Care, Inc., was designed ...
... ESTATES, Ill., Sept. 20 With flu season just around the ... flu clinics are now open through Nov. 15. Customers can receive ... of the more than 900 Kmart Pharmacy walk-in flu ... are free for those covered by Medicare Part B. Those who ...
Cached Medicine Technology:South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 2South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 3South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 4South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 5South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 6South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 7South Carolina Optometrists Partner with State Legislators and Local Mayors in Improving Infant Eye and Vision Care 8Kmart Pharmacy Announces Availability of Flu Shots at Walk-In Flu Clinics 2Kmart Pharmacy Announces Availability of Flu Shots at Walk-In Flu Clinics 3
Six inch wide elastic belt transfers the apron weight off the shoulders. 0.5mm front and 0.25mm back with a generous overlap for double protection. Shoulder pads included. Also available without wide...
6" wide elastic belt transfers the apron weight off the shoulders to the hips making this apron the most comfortable for long procedures. Adjustable. Velcro keeps apron snug....
... single-use, direct current stimulator ... 0.5, 1.0, and 2.0mA ... needle as the grounding ... flow" confirmation light is ...
The NS242 is a base level constant current Conventional Peripheral Nerve Stimulator only. It uses conventional stimulation patterns only to monitor neuromuscular blocks i.e. Single Twitch, Train of F...
Medicine Products: