Navigation Links
Medication does not help prevent ED following radiation therapy for prostate cancer
Date:4/1/2014

Among men undergoing radiation therapy for prostate cancer, daily use of the erectile dysfunction drug tadalafil, compared with placebo, did not prevent loss of erectile function, according to a study in the April 2 issue of JAMA.

Erectile dysfunction (ED) is a common condition resulting from many causes, including prostate cancer treatment. An estimated 40 percent of men report ED after radiation therapy, and half of all men use erectile aids following this therapy. Tadalafil is used to treat erectile dysfunction after prostate cancer treatment, but its role as a preventive agent has not been determined, according to background information in the article.

Thomas M. Pisansky, M.D., of the Mayo Clinic, Rochester, Minn., and colleagues with the Radiation Therapy Oncology Group, randomly assigned 242 men with prostate cancer to receive tadalafil (5 mg) or placebo daily for 24 weeks starting with radiation therapy (either with external radiotherapy [63 percent] or brachytherapy [37 percent]). The study was conducted at 76 sites in the United States and Canada; participants were recruited between November 2009 and February 2012, with follow-up through March 2013.

Between weeks 28 and 30 after the start of radiation therapy, among evaluable participants, 79 percent who received tadalafil retained erectile function compared with 74 percent who received placebo, an absolute difference of 5 percent. A significant difference between groups was also not observed at 1 year (72 percent vs 71 percent). Tadalafil was not associated with improved overall sexual function or satisfaction, and partners of men assigned tadalafil noted no significant effect on sexual satisfaction.

"These findings do not support the scheduled once-daily use of tadalafil to prevent ED in men undergoing radiotherapy for localized prostate cancer," the authors write.

They add that alternative strategies to prevent ED in this context appear warranted,
'/>"/>

Contact: Joe Dangor
dangor.yusuf@mayo.edu
507-266-0696
The JAMA Network Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Forgoing Medication, for Babys Sake
2. Parents poor math skills may lead to medication errors
3. Reducing off-label use of antipsychotic medications may save money
4. Common acne medication doubles risk of eye infection
5. Misuse of over-the-counter pain medication is potential health threat
6. Genes predict if medication can help you quit smoking
7. Acne Medication May Raise Risk of Eye Infections
8. New delivery method improves efficacy of 2 common Parkinsons disease medications
9. Mount Sinai researcher finds timing of ADHD medication affect academic progress
10. Actos Bladder Cancer Lawsuit Filed in Louisiana Alleging Woman Used Diabetes Medication and Contracted Bladder Cancer, Consumer Justice Foundation Reports
11. Physicians dont adequately monitor patients medication adherence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... ... 2015 , ... In an article published July 30th by the ... New Orleans, highlighting a security firm that is tasked with providing supplemental protection. Called ... who worked with the city to provide private security when it is needed in ...
(Date:8/27/2015)... ... August 27, 2015 , ... Allegheny General Hospital (AGH), part ... medical centers in the United States to receive international recognition for an advanced, ... Extracorporeal Life Support Organization (ELSO) , an international consortium of healthcare institutions dedicated ...
(Date:8/27/2015)... Michigan (PRWEB) , ... August 27, 2015 , ... On ... returned for the second year as sponsor of the “Music With A Mission” benefit ... raise money for music education programs in the underfunded school districts of Mendon and ...
(Date:8/27/2015)... ... 27, 2015 , ... Dr. Jennifer Arnold, co-star of “The Little Couple” and ... 3rd Annual MPN Heroes™ recognition event on Friday, Dec. 4, prior to ... honoring eight heroes who have made significant contributions in the field of rare blood ...
(Date:8/27/2015)... ... August 27, 2015 , ... Infocast is ... October 27-29, 2015 in San Jose, CA. The first event dedicated to ... the void that exists where battery development and energy storage innovation are concerned. ...
Breaking Medicine News(10 mins):Health News:Article on New Orleans Security Force Highlights the Abilities and Flexibility of Private Security, says Spear Security Inc. 2Health News:International Organization Honors Allegheny General Hospital's Advanced Lifesaving Program for Cardiac and Respiratory Failure 2Health News:International Organization Honors Allegheny General Hospital's Advanced Lifesaving Program for Cardiac and Respiratory Failure 3Health News:International Organization Honors Allegheny General Hospital's Advanced Lifesaving Program for Cardiac and Respiratory Failure 4Health News:Best Drug Rehabilitation Interviews Madd Hoss Jackson at the 2015 "Music With A Mission" Benefit Concert 2Health News:Dr. Jennifer Arnold of ‘The Little Couple’ to Keynote 3rd Annual MPN Heroes™ Recognition Event in Orlando 2Health News:Dr. Jennifer Arnold of ‘The Little Couple’ to Keynote 3rd Annual MPN Heroes™ Recognition Event in Orlando 3Health News:Dr. Jennifer Arnold of ‘The Little Couple’ to Keynote 3rd Annual MPN Heroes™ Recognition Event in Orlando 4Health News:Infocast Hosting First Conference Dedicated to Powering Wearable Devices & the IoT 2
... 1960s, surgeons experimented by transplanting chimpanzee organs into humans in ... a baboon heart and survived 20 days. Since then, doctors// ... organs, tissues and cells to treat various diseases, all with ... surrounding cross-species transplant -- also known as xenotransplantation. ...
... common treatment option for HIV patients is associated with ... a new study. However, researchers say the benefit of ... for most patients. ,Combination antiretroviral therapy substantially ... AIDS. Before this therapy was available, the annual mortality ...
... for centuries, doctors say. But only recently has it been ... migraines or neck- and head-squeezing tension headaches //that are present ... think it sounds like just another excuse to skip school. ... freshman from St. Cloud, Minnesota, know how serious the condition ...
... is a common health problem worldwide. Both osteoarthritis and ... There is no cure for arthritis and no effective ... study could help lead doctors towards a drug to ... molecular pathway and an enzyme that play a pivotal ...
... caused a recent outbreak of Hepatitis A in Pennsylvania ... ,Bill Zavertnik, Chi-Chi's chief operating officer, said in ... were not the source of the outbreak, that there ... outbreak and that it was an isolated incident. , ...
... new study shows a new drug alternative to warfarin in ... The research shows the drug ximelagatran appears to be as ... for people at high risk of stroke because of its ... include an increased risk of bleeding and a possible interaction ...
Cached Medicine News:Health News:Animals can give us a second chance at life 2Health News:HIV Treatment Said to Increase Heart Attack Risk 2Health News:Finding relief from Excruciating Headaches a challenge 2Health News:Finding relief from Excruciating Headaches a challenge 3
(Date:8/27/2015)... PLYMOUTH MEETING, Pa. , Aug. 27, 2015 /PRNewswire-USNewswire/ ... is decommissioning the Da Vinci S™ surgical robot, hospitals ... robot replacement plans. They also need to see where ... right procedures on the right patients? Have they adopted ... their robotic surgery program in the future? ...
(Date:8/27/2015)... , Aug. 27, 2015   NineSigma the ... drive over $450M in estimated overall revenue growth and anticipates ... Ohio Third Frontier Open Innovation Incentive (OII). ... awarded NineSigma a grant of over $2 million to accelerate ... companies between $10 Million and $1 Billion in revenues. To ...
(Date:8/27/2015)... The nation,s newest Actos trial gets underway Thursday, ... courtroom.  Attorneys representing two southern Nevada ... including death, after using the diabetes drug Actos. ... company knew, that their drug Actos caused an increased risk ... order to hold Takeda responsible it is appropriate to seek ...
Breaking Medicine Technology:ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 2ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 3State of Ohio and NineSigma Collaborate to Drive Regional Economic Growth and Job Creation 2State of Ohio and NineSigma Collaborate to Drive Regional Economic Growth and Job Creation 32 Billion Dollar Verdict Sought In Actos Trial 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: