Navigation Links
Medication adherence improves blood pressure control in chronic kidney disease
Date:11/3/2010

CINCINNATIResearchers at the University of Cincinnati (UC) and the Cincinnati Veterans Affairs (VA) Medical Center have found that about one-third of chronic kidney disease patients who are prescribed therapies for high blood pressure do not often adhere to treatments.

This report was published in the Nov. 2 online edition of the American Journal of Nephrology.

The study, led by researchers at UC and the Cincinnati VA, showed that treatment of hypertension in patients with chronic kidney disease continues to be a challenge in their care and that by simply improving medication adherence, outcomes would improve greatly.

Chronic kidney disease is the slow loss of kidney function over time. The main function of the kidneys is to remove wastes and excess water from the body. Ongoing hypertension is often associated with kidney disease.

"Hypertension, or high blood pressure, is probably the most important modifiable risk factor in chronic kidney diseasea precursor to end-stage renal disease that is associated with increased risk of morbidity and mortality," says Charuhas Thakar, MD, associate professor in the division of nephrology and hypertension at UC and chief of the renal section at the Cincinnati VA. "In chronic conditions, such as hypertension, whether or not a patient takes the correct dosage and amount of their hypertension medication is critical in reaching treatment goals.

"Patterns of medication adherence for these agents and their impact on blood pressure in practice settings were not previously well studied. We wanted to find out if medication adherence could make a difference on outcomes in kidney disease patients."

Using two years worth of data from patients seeking ambulatory care at the VA, researchers examined 7,227 chronic kidney disease patients who received at least one blood pressure medication prescription. Outpatient blood pressure measurements were averaged as high (more than 130/80 mm of Hg) versus normal, based on the national guidelines for hypertension management in kidney disease.

Medication adherence was calculated using medication possession ratio, meaning the actual treatment days divided by the total possible treatment days.

"Good versus poor medication adherence groups were compared for differences in demographic, co-morbid and laboratory variables," says Kristen Schmitt, chief of pharmacy at the Cincinnati VA and the lead author of the study. "Results showed that while 67 percent of patients took their medication properly, a total of 33 percent of patients had poor medication adherence. More importantly, those with poor adherence were 23 percent more likely to have sub-optimal blood pressure control during the entire two-year study period."

"With this data, we hope to develop a multidisciplinary approach to help kidney disease patients adhere to their prescribed blood pressure medications. This will not only improve their clinical outcomes but will also help in reducing costs of care," she continues.

"Although the results represent a large sample of patients, they are derived from a single center," adds Thakar. "Further investigations are needed to accurately assess the impact of medication adherence on cardiovascular and renal outcomes in practice."


'/>"/>

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center
Source:Eurekalert

Related medicine news :

1. Certain pain medications do not appear to be associated with skin cancer risk
2. Study supports alternative anti-seizure medication following acute brain injury
3. Enovate Announces New Lightweight Medication Cart Series
4. PharmacyChecker.com Begins Blog About Americans' Access to Affordable Medication
5. NACDS RxIMPACT "Hill Day" Features More Advocates Increased Focus on Medication Adherence
6. South Dakota Students with Asthma Can Breathe Easier After New Law Allows Self-Administered Medications
7. RememberItNow! Launches Mobile Medication Reminder and eHealth Service
8. Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees
9. New England Journal of Medicine Article Trumpets “Priority” Status of Helping Patients Take Medications Correctly
10. Pollen.com Reports Five U.S. Cities with Highest Pollen Activity -- Total Prescriptions for Allergy Medications 3.7% Higher than Last Year
11. Low vitamin D levels associated with more asthma symptoms and medication use
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... March 23, 2017 , ... The founders of ... awarded as winners of American Dreams & Good Housekeeping Seal Initiative, a nationwide ... HSN and Good Housekeeping. , Steven Wang, MD ., a renowned dermatologist ...
(Date:3/23/2017)... , ... March 23, 2017 , ... The Boulevard is ... - 2pm. All events will be located in the Main West Entrance of ... no-cost Child ID event. No appointment is necessary and each child with a parent ...
(Date:3/23/2017)... ... ... “Beyond and Back”: a true-life testimony of tragedy and the miraculous power ... Rose, a wife, mother and grandmother committed to sharing her many spiritual adventures which ... new book presents actual events in the life of her family, which validate her ...
(Date:3/23/2017)... ... 2017 , ... Ogden Clinic, the largest multi-specialty group in ... to expand its focus on patient care by providing an advanced check-in and ... Ogden Clinic, we are working to become a different type of provider, one ...
(Date:3/23/2017)... ... ... Corruption”: a simple and strong explanation of the God’s love. “More Corruption” is the ... asked by God to write a book about Him. , She says, “I’m fed up ... commitment to the Lord God. They have not walked in my shoes and I know ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... Global Colposcope Market by Manufacturers, Countries, Type and Application, ... especially in North America , Europe ... America , Middle East and ... manufacturers, regions, type and application. ... Browse 190 Tables and Figures, 19 Major Company Profiles, ...
(Date:3/23/2017)... NeuroVive Pharmaceutical AB (Nasdaq Stockholm: NVP, ... English version of the Annual report for 2016 is now ... ... NeuroVive Pharmaceutical AB is a leader in mitochondrial medicine. ... medicines that preserve mitochondrial integrity and function in areas of ...
(Date:3/22/2017)...  DarioHealth Corp. (NASDAQ: DRIO), a leading global ... data solutions, today reported financial and operational results ... December 31, 2016. 2016 Highlights ... 241% compared to the full year 2015  ... entire year  Direct-to-consumer model launched ...
Breaking Medicine Technology: