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Medco, LabCorp Strike Strategic Agreement for Research on Personalized Medicine and Pharmacogenomics
Date:10/22/2007

Collaboration to Explore Clinical Uses of Personal Genetics and Tamoxifen

FRANKLIN LAKES, NJ and BURLINGTON, NC, Oct. 22 /PRNewswire-FirstCall/ -- Medco Health Solutions Inc. (NYSE: MHS) and Laboratory Corporation of America(R) Holdings (LabCorp(R)) (NYSE: LH) announced a strategic research agreement today to advance the field of pharmacogenomics, an emerging science integrating genetics and drug treatment that is leading the way toward personalized medicine. The research effort, which will be centered on tamoxifen, is the latest in a rapidly growing field of studies linking individual genetics to the safety and efficacy of specific prescription drugs. Genotyping for the study will be performed using the FDA-cleared Roche AmpliChip(R) CYP450 test.

Tamoxifen, a drug that deprives certain tumors of estrogen needed for their growth, treats some forms of breast cancer and prevents the disease from occurring in some women at high risk for the condition. Approximately 10 percent of women using tamoxifen do not fully benefit from the drug because of variations in genes encoding drug metabolizing enzymes.

"This agreement is between two industry leaders that are at the forefront of the movement toward personalized medicine. Companion diagnostics can help physicians determine which drug will be most effective for particular patients. This will benefit patients and lower healthcare costs by improving outcomes, enhancing safety and reducing ineffective drug regimens," said My
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SOURCE Medco Health Solutions Inc.
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