Navigation Links
Mechanism of breathing muscle 'paralysis' in dreaming sleep identified
Date:11/15/2012

The brain chemical mediating this powerful inhibition of breathing muscle activity in REM sleep is acetylcholine, acting via muscarinic receptors that are functionally linked to a particular class of potassium channel.

"Since REM sleep recruits mechanisms that can abolish or suppress tongue muscle activity during periods of REM sleep and cause obstructive sleep apnea, identification of a mechanism mediating this inhibition is a significant discovery," said Dr. Horner.

"This newly identified process has fundamental implications for understanding the common and serious problems of snoring and other breathing problems such as obstructive sleep apnea, which are worse in REM sleep," said Dr. Horner. "Moreover, identifying the fundamental mechanism responsible for the shutting down of a muscle in sleep that is critical for effective breathing also identifies a rational drug target designed to prevent this inactivity and so prevent obstructive sleep apnea and other sleep-related breathing problems."


'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Joslin scientists identify important mechanism that affects the aging process
2. Researchers gain better understanding of mechanism behind tau spreading in the brain
3. Aggregating instead of stabilizing: New insights into the mechanisms of heart disease
4. Study supports urate protection against Parkinsons disease, hints at novel mechanism
5. Probing the mechanism of ADAM28-mediated cancer metastasis
6. Fruit flies reveal mechanism behind ALS-like disease
7. Scientists discover mechanism that promotes lung cancer growth and survival
8. Abnormal gene product associated with prostate cancer generated by unusual mechanism
9. New mechanism of bacterial pathogenesis discovered
10. Scientists identify new cancer stem cell mechanism
11. Zebrafish reveal promising mechanism for healing spinal cord injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... ... August 04, 2015 , ... Data2Life , a ... designed to provide pharmaceutical and healthcare organizations with advanced intelligence on drug effects. ... from regulatory filings (including the FDA and HealthCanada), social media and anonymized clinical ...
(Date:8/4/2015)... ... August 04, 2015 , ... Armadale Capital ... announced the closing of a $118 million FHA-insured loan modification refinancing for Johnston ... Smithfield and Clayton, North Carolina. JHSC is a joint venture of Johnston ...
(Date:8/4/2015)... ... August 04, 2015 , ... Updated enrollment data on the top ... can now be accessed at http://www.AISHealth.com . The data is free to all ... 2015, the tables and charts on the website’s “Data” section include:, ...
(Date:8/4/2015)... , ... August 04, 2015 , ... ... party supplies, arts and crafts, toys, novelties, and school supplies, has developed engaging ... , The exclusive collection includes student rewards, classroom decorations, crafts and ...
(Date:8/4/2015)... ... August 04, 2015 , ... Mercy Health (formerly Catholic Health Partners) – a Catholic healthcare ministry ... You Be Well videos to preparing high school athletes for fall sports. , In a ... such as:, , What steps to take to help prevent injuries ...
Breaking Medicine News(10 mins):Health News:Data2Life Announces New System for Advance Intelligence on Drug Events 2Health News:Data2Life Announces New System for Advance Intelligence on Drug Events 3Health News:Armadale Capital Inc. Refinances $118 Million for Johnston Health Services Corporation 2Health News:Armadale Capital Inc. Refinances $118 Million for Johnston Health Services Corporation 3Health News:Atlantic Information Services Website Offers Up-to-Date U.S. Health Plan Enrollment Data 2Health News:Oriental Trading Company Brings The World of Eric Carle Characters to Educators Through Classroom Supplies 2Health News:Oriental Trading Company Brings The World of Eric Carle Characters to Educators Through Classroom Supplies 3Health News:Mercy Health Video Provides Helpful Information for High School Athletes 2
... PALO ALTO, Calif., June 10 Telik, Inc.,(Nasdaq: ... Patent Office has issued,notices of allowance for two ... lead clinical candidates, TELINTRA(R). Corresponding,applications have already issued ... are pending in major countries worldwide., TELINTRA ...
... 10 AMERIGROUP,Corporation (NYSE: AGP ) announced today ... to $2.45 per diluted share pending completion of its,rate ... the Company will present at the Goldman Sachs Healthcare,Conference ... of 2008, AMERIGROUP disclosed higher medical costs,in the middle ...
... Calif., June 10 The Law Offices of Christopher,Grell ... HLF ) in the,Superior Court of the State of ... 29-year-old woman who acquired acute liver problems after,taking Herbalife ... that manufacture,Herbalife products and ingredients, alleges that Phillis Chen, ...
... Appeals Affirms No Infringement, PITTSBURGH, June 10 ... U.S. Court of Appeals for the Federal Circuit has,affirmed ... 10 mg and 20,mg Omeprazole delayed-release capsules do not ... generic version of,AstraZeneca LP,s Prilosec(R)., Mylan launched its ...
... more people today can,t,afford health insurance. Being uninsured ... This National Men,s Health Week, Pfizer wants to ... are uninsured but,need medicine prescribed by their doctors., ... PFE ) at:, http://media.medialink.com/WebNR.aspx?story=35208 , Registered ...
... keep addiction affordable, study says , , TUESDAY, ... United States have declined in recent years, but sales ... decline in cigarette sales by 30 percent, a Harvard ... federal government data and found that between 2000 and ...
Cached Medicine News:Health News:Telik Announces Patents on Compounds Related to TELINTRA 2Health News:AMERIGROUP Provides Status on Tennessee Rate Increase and Effect on 2008 Guidance 2Health News:AMERIGROUP Provides Status on Tennessee Rate Increase and Effect on 2008 Guidance 3Health News:AMERIGROUP Provides Status on Tennessee Rate Increase and Effect on 2008 Guidance 4Health News:AMERIGROUP Provides Status on Tennessee Rate Increase and Effect on 2008 Guidance 5Health News:Herbalife Sued for Negligence and Fraud by Victim 2Health News:Decline in Cigarette Sales Offset by Use of Alternative Products 2
(Date:8/4/2015)... Aug. 04, 2015 ... the addition of Jain PharmaBiotech,s new report ... to their offering. This report describes ... veterinary medicine and pharmaceuticals as well as improvement ... important in the application of biotechnology to manage ...
(Date:8/4/2015)... 2015 ANI Pharmaceuticals, Inc. ("ANI") (NASDAQ: ... and six months ended June 30, 2015 and updated ... its earnings conference call this morning, August 4, 2015, ... can join the call by dialing (855) 582-8078. The ... , Year-to-date net revenues of $38.3 million, an increase ...
(Date:8/3/2015)... 3, 2015  Landauer, Inc. (NYSE: LDR ), ... and monitoring, outsourced medical physics services and high quality ... results for the fiscal third quarter 2015 after the ... The Company will also host a conference call ... a.m. Central Time (10:00 a.m. Eastern Time). Investors may ...
Breaking Medicine Technology:Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 2Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 3ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 2ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 3ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 4ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 5ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 6ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 7ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 8ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 9ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 10ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 11ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 12ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 13ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 14ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 15ANI Pharmaceuticals Reports Second Quarter and Year-To-Date 2015 Results and Highlights 16Landauer, Inc. Announces Date And Time For Announcement Of Fiscal Third Quarter 2015 Results And Conference Call 2
... , , GLEN BURNIE, Md., Dec. 1 ... for home testing and evaluation of sleep-disordered breathing, today announced ... officer. Hassett was most recently president of Matria Healthcare, ... into a $350 million industry leader in total population health, ...
... 1 Exagen Diagnostics, Inc., a molecular diagnostics laboratory ... announced the appointment of Scott Glenn as chairman of ... , Prior to joining Exagen, Glenn was managing partner ... of successful biomedical companies including Prometheus Laboratories, Santarus, Dexcom, ...
Cached Medicine Technology:Sleep Solutions, Inc. Names Richard Hassett, M.D., New CEO 2Sleep Solutions, Inc. Names Richard Hassett, M.D., New CEO 3Scott Glenn Joins Exagen Diagnostics as Chairman and CEO 2
The ACCU-Beam® line of Surgical Microscope Accessories includes digital camera adaptors, beam splitters, objective lenses, fiber optic cables, and fiberoptic retrofits....
The ACCU-Beam® line of Surgical Microscope Accessories includes digital camera adaptors, beam splitters, objective lenses, fiber optic cables, and fiberoptic retrofits....
The ACCU-Beam® line of Surgical Microscope Accessories includes digital camera adaptors, beam splitters, objective lenses, fiber optic cables, and fiberoptic retrofits....
... line of Surgical Microscope Accessories includes digital ... optic cables, and fiberoptic retrofits. TTI Medical's ... no. 5,264,928) is the only adaptor that ... on the same adaptor body. It is ...
Medicine Products: