Navigation Links
Measles virus may be effective prostate cancer treatment
Date:1/21/2009

Rochester, Minn. January 21, 2009 A new study appearing in The Prostate has found that certain measles virus vaccine strain derivatives, including a strain known as MV-CEA, may prove to be an effective treatment for patients with advanced prostate cancer. The findings show that this type of treatment, called virotherapy, can effectively infect, replicate in and kill prostate cancer cells.

Prostate cancer is a leading cause death among males in the western world. It is currently the second most common cause of cancer-related deaths among American men with 186,320 new cases and 28,660 deaths expected to be recorded in 2008. A sizeable proportion of these patients ultimately relapse, with a 5-year failure rate for treatment ranging from 14 to 34 percent. No curative therapy is currently available for locally advanced or metastatic prostate cancer.

The median survival time of MV-CEA-treated mice in the study almost doubled compared to the controls, and complete tumor regression was observed in one-fifth of treated animals.

"Based on our preclinical results as well as the safety of measles derivatives in clinical trials against other tumor types, these viral strains could represent excellent candidates for clinical testing against advanced prostate cancer, including androgen resistant tumors," says Evanthia Galanis, M.D., of the Mayo Clinic, senior author of the study. The study was supported by the Mayo Clinic Specialized Program of Research Excellence (SPORE) in prostate cancer.

These oncolytic strains of measles virus, represent a novel class of therapeutic agents against cancer that demonstrates no cross-resistance with existing treatment approaches, and can therefore be combined with conventional treatment methods.

Because primary tumor sites are easily accessible in prostate cancer, locally recurrent disease represents a promising target for virotherapy approaches. The virotherapy agent can easily be appl
'/>"/>

Contact: Sean Wagner
medicalnews@bos.blackwellpublishing.net
781-388-8550
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Europe Unlikely to Meet Measles Goals: Report
2. Worldwide Measles Deaths Drop Dramatically
3. Global Measles Deaths Drop By 74%
4. Measles Initiative Supports Disease Prevention for Children in Chinas Earthquake Zone
5. $9 Million Committed to Bolster Worldwide Measles Initiative
6. Study firmly shows no connection between measles, mumps, rubella (MMR) vaccine and autism
7. Measles Cases Highest Since 1996
8. Measles Outbreak Rises to 64 Cases, Most Since 2001
9. CDC Urges Travelers to Israel to Protect Themselves from Measles
10. Government of Madagascar and Coalition of Global Partners Launch Measles and Malaria Prevention Campaign
11. Engineered virus targets and kills apparent cancer stem cells in neuroblastoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... 2014 The inaugural single day event ... Hotel New Otani Tokyo Gardens in Tokyo. Clinical data scientists ... and validation. , The second single day event in ... offices in Shanghai. The clinical data scientists attending this event ... figures and listings, which display data collected in clinical studies ...
(Date:9/23/2014)... "The primary purpose of the CALL LIGHT ... from Sacramento, Ca.. "Call lights are often found on the ... the IV pole out of the patient's reach. In order ... whenever they need it, I created this caddy." , She ... call device within easy reach. The accessory ensures that the ...
(Date:9/23/2014)... Downingtown, PA (PRWEB) September 24, 2014 ... traumatic stress disorder (PTSD) – and how it can ... 31, was deployed in Iraq in 2006. His platoon ... home in 2008, he was diagnosed with combat-related PTSD ... withdrawn, I was angry, and I had distanced myself ...
(Date:9/23/2014)... Karen Pallarito HealthDay Reporter ... if doctors and hospitals got paid for providing better ... better data for making informed health choices. A ... is headed. The report, from the IMS Institute for ... -- recent events expected to alter the delivery of health ...
(Date:9/23/2014)... 2014 What information do patients ... Quality Forum (NQF) released a report ( http://bit.ly/1DwekE9 ... an infographic ( http://bit.ly/1tX3lzA ) resulting from an ... how patients define affordability, and what information and ... best possible healthcare at the lowest possible cost. ...
Breaking Medicine News(10 mins):Health News:PhUSE Further Expands its Global Community Into the Asian Region 2Health News:Virtual Reality software to help treat PTSD 2Health News:Virtual Reality software to help treat PTSD 3Health News:Report Identifies Game Changers for U.S. Health Care 2Health News:Report Identifies Game Changers for U.S. Health Care 3Health News:Finding Affordable Care: Asking the Right Question is Key 2
... , , , ROCHESTER, Minn., Sept. ... is the focus of a Perspectives article in ... 23, 2009, and in the print issue on Oct. 1, 2009. , ... , "We must hold physicians and other providers accountable for ...
... from the dried venom secreted by the skin glands of ... those normally administered, and may slow disease progression in some ... D. Anderson Cancer Center. The results from ... M. D. Anderson and Fudan University Cancer Hospital in Shanghai, ...
... The Weill Cornell Institute of Geriatric Psychiatry at ... the largest grant in its 20-year history. One ... million, five-year "Center Grant" from the National Institute ... investigators to advance their pioneering work in understanding ...
... registered in the past 30 years, cardiovascular disease (CVD) remains the ... In the EU, experts reveal that striking disparities still exist ... with regard to national prevention policies. In view of this, there ... tackle heart disease and stroke. The message coincides with ...
... ... ... -- Whether in a quest for beauty or out of necessity, millions of Americans will ... technologies, and research will be presented at Plastic Surgery 2009, the annual scientific meeting of ...
... flu not effective , THURSDAY, Sept. 24 (HealthDay News) ... give the wrong dose of Tamiflu to their children ... dosing instructions don,t always coincide with the measurement markings ... , The warning letter, penned by scientists from Northwestern ...
Cached Medicine News:Health News:Mayo Clinic Offers Perspective on Health Care Reform in New England Journal of Medicine 2Health News:M. D. Anderson examines use of toad venom in cancer treatment 2Health News:M. D. Anderson examines use of toad venom in cancer treatment 3Health News:Weill Cornell Institute for Geriatric Psychiatry awarded $10 million grant 2Health News:Weill Cornell Institute for Geriatric Psychiatry awarded $10 million grant 3Health News:Weill Cornell Institute for Geriatric Psychiatry awarded $10 million grant 4Health News:World Heart Day resonates with recent experts' findings on CVD and EU institutions' determination to promote heart health 2Health News:World Heart Day resonates with recent experts' findings on CVD and EU institutions' determination to promote heart health 3Health News:American Society Of Plastic Surgeons Hosts 78th Annual Meeting 2Health News:American Society Of Plastic Surgeons Hosts 78th Annual Meeting 3Health News:American Society Of Plastic Surgeons Hosts 78th Annual Meeting 4Health News:Letter Warns About Tricky Dosing With Liquid Tamiflu for Kids 2Health News:Letter Warns About Tricky Dosing With Liquid Tamiflu for Kids 3
(Date:9/23/2014)... , Sept. 23, 2014 ... of the "Physician Office Laboratory Markets, 3rd ... This report, Physician Office Laboratory Markets is ... the IVD industry. Physician office laboratories are diverse ... simply perform reimbursable, in-office pregnancy and glucose tests. ...
(Date:9/23/2014)... The Pennsylvania State Police will accept unwanted, expired ... of National Prescription Drug Take-Back Day. The service is ... Day is a national initiative, conducted in partnership with ... the public to dispose of expired, unused or unwanted ... From 10 a.m. to 2 p.m., unwanted ...
(Date:9/23/2014)... , Sept. 23, 2014 Research and ... "Biopharmaceutical and Vaccine Production Markets" report to their ... new therapies and vaccines - including products to treat ... still huge challenges during the final stages of clinical ... and how to risk production capital to upscale while ...
Breaking Medicine Technology:Physician Office Laboratory Markets, 3rd Edition 2Physician Office Laboratory Markets, 3rd Edition 3Biopharmaceutical and Vaccine Production Markets 2Biopharmaceutical and Vaccine Production Markets 3
... Inc. (OTC BB: NSPR) ("Inspire" or the "Company"), ... and commercialization of its proprietary stent platform technology, ... summary of  three years collective data will be ... Transcatheter Cardiovascular Therapeutics (TCT) conference. The conference is ...
... Express Scripts, Inc., one of the largest ... Rexam as its 2011 Supplier of the Year. ... This award recognizes suppliers who have a ... continuous improvement in supplier relationship management, quality, service, ...
Cached Medicine Technology:InspireMD to Sponsor Satellite Symposium Breakfast Meeting Chaired by Dr. Gregg W. Stone November 9th at TCT 2011 2InspireMD to Sponsor Satellite Symposium Breakfast Meeting Chaired by Dr. Gregg W. Stone November 9th at TCT 2011 3InspireMD to Sponsor Satellite Symposium Breakfast Meeting Chaired by Dr. Gregg W. Stone November 9th at TCT 2011 4Rexam Chosen as Express Scripts' Supplier of the Year 2
... Bio-Rad isotopic anemia ... and minimal ,pipetting steps ... information about the processes ... and the benefit to ...
... Bio-Rad isotopic anemia assays ... minimal ,pipetting steps for ... about the processes ,involved ... the benefit to your ...
... The ImmunoDOT Autoimmunity Screening Panel ... test for screening and detection,of autoantibodies ... DNA, SS-A/SS-B, RNP/Sm) in serum, and ... diagnosis of systemic lupus erythematosus (SLE), ...
The MESACUP ANA Test Kit is a semi-quantitative enzyme-linked immunosorbent assay,(ELISA) for the detection of specific anti-nuclear antibodies in human serum as an aid in,the determination of autoim...
Medicine Products: