Navigation Links
McMaster study sheds light on how stem cells develop into blood cells
Date:3/5/2009

Hamilton, ON (March 3, 2009) - How messages sent within stem cells through a specific communication pathway can trigger the cells to specialize and become blood cells in humans, has been discovered by scientists of the McMaster Stem Cell and Cancer Research Institute.

The finding, to be published in the March 6 issue of Cell Stem Cell, marks the first time scientists have demonstrated the importance of the pathway, known as the noncanonical Wnt, in inducing blood formation in humans or any other species. The pathway works by organizing the cells so that they can respond to signals for blood development.

Mick Bhatia, director of the McMaster Stem Cell and Cancer Research Institute, is the lead investigator of the study, which involved researchers from McMaster University, Howard Hughes Medical Institute and the Randall T. Moon Institute for Stem Cell and Regenerative Medicine at the University of Washington.

"By directing cell differentiation, this method provides the most efficient way to produce blood cells that we are aware of to date," said Bhatia, a professor in the Department of Biochemistry and Biomedical Sciences at McMaster.

"The work also provides a new way to make blood from human stem cells that could be used for clinical applications to regenerate the immune and blood system in patients, including those with leukemia or undergoing cancer therapies that indirectly destroy the immune and blood system."

Stem cells are the building blocks of every organ and tissue in the body. Through the process of cellular differentiation, moving from a less specialized cell to a more specialize cell, stem cells have the ability to become any type of cell in the body including bone, muscle and blood cells.


'/>"/>

Contact: Veronica McGuire
vmcguir@mcmaster.ca
90-552-591-402-2169
McMaster University
Source:Eurekalert

Page: 1

Related medicine news :

1. Mayo Clinic, McMaster University Research Review Shows Internet-based Instruction Effective for Teaching Health Care Professionals
2. McMaster test detects the most prevalent respiratory viruses
3. United Spinal Association Report Reveals the Importance of Studying Multiple Sclerosis in Children: Developing New Insights into MS in Adults
4. Penile extender increased flaccid length by almost a third says independent clinical study
5. UPDATE: NewCardio Leadership to Present Clinical Data of Fully Automated QTinno(TM) Study at American College of Cardiology Annual Meeting
6. Study finds injectable birth control causes significant weight gain and changes in body mass
7. Kidney Disease Increases the Risk of Stroke in Patients With the Most Common Type of Heart Arrhythmia, According to Kaiser Permanente Study
8. Is one diet as good as another? U of I study says no and tells you why
9. NewCardio Leadership to Present Clinical Data of Fully Automated QTinno(TM) Study at American College of Cardiology Annual Meeting
10. Levels of Trace Pharmaceuticals in Drinking Water Too Low to Impact Human Health According to Water Research Foundation Study
11. His and hers: Study examines the role of gender in the stigma of mental illness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... , ... December 05, 2016 , ... ... it has been featured in SuperbCrew magazine, a leading online tech news platform ... This interview, now featured on SuperbCrew.com, explores the state of enterprise mobility security ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... today that nominations will be accepted from December 5, 2016 through March ... Awards include the Information Security Executive® of the Year, which recognizes executives ...
(Date:12/5/2016)... ... December 05, 2016 , ... Researchers at Johns Hopkins All ... brains of young athletes. Over the course of three years, researchers will study concussions ... guards. The mouth guards, equipped with special sensors, will track the location and force ...
(Date:12/5/2016)... ... December 05, 2016 , ... Worldwise ®, a leading ... firm kathy ireland® Worldwide for five additional years, announced by Kevin Fick, Worldwise ... licensing agreement three years ago to design and develop the kathy ireland® Loved ...
(Date:12/5/2016)... ... December 05, 2016 , ... “Epilepsy Awareness,” which can be ... sparks a conversation about epilepsy, bearing down on the social stigma and lack ... diagnosed with epilepsy within their lifetime. With such a large percentage of people ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... Israel , December 5, 2016 ... identifying, in-licensing and developing promising therapeutic candidates, presents positive Phase ... BL-8040, the Company,s leading oncology platform at the ongoing 58th ... San Diego, California . ... , , ...
(Date:12/5/2016)... TAIPEI, Taiwan , Dec. 5, 2016 ... showed non-inferiority to hydroxyurea (HU) in Complete Hematologic Response (CHR) ... tolerability profile of ropeginterferon alfa-2b versus HU ... long-term follow-up trial CONTINUATION-PV to obtain European marketing authorization in ... this data to the FDA as it seeks approval for ...
(Date:12/4/2016)... HOUSTON , Dec. 3, 2016   Pairnomix, LLC, ... Precision Medicine Alliance (PEPMA) recognized by the White House, today ... individualized approach to the identification of candidate therapies for a ... SCN8A gene were presented at the 70 th ... in Houston, TX , December 2-6, 2016.  ...
Breaking Medicine Technology: