Navigation Links
McGill researchers report breakthrough in rapid malaria detection
Date:12/19/2007

A research team led by Dr. Paul Wiseman of the Departments of Physics and Chemistry at McGill University has developed a radically new technique that uses lasers and non-linear optical effects to detect malaria infection in human blood, according to a study published in the Biophysical Journal. The researchers say the new technique holds the promise of simpler, faster and far less labour-intensive detection of the malaria parasite in blood samples.

Malaria is a vector-borne infectious disease spread by parasites of the genus Plasmodium. Most common in tropical and subtropical regions, it is a global scourge with 350 to 500 million new cases and one to three million fatalities reported annually. Most of the fatalities are concentrated in sub-Saharan Africa, where the resources and trained personnel currently required to accurately diagnose the disease are spread the thinnest.

Current detection techniques require trained technicians to stain slides, look for the parasites DNA signature under the microscope, and then manually count all the visible infected cells, a labourious process dependent on the skill and availability of trained analysts. By contrast, the proposed new technique relies on a known optical effect called third harmonic generation (THG), which causes hemozoin a crystalline substance secreted by the parasite to glow blue when irradiated by an infrared laser.

People who are familiar with music know about acoustic harmonics, said Dr. Wiseman. "You have a fundamental sound frequency and then multiples of that frequency. Non-linear optical effects are similar: if you shine an intense laser beam of a specific frequency on certain types of materials, you generate multiples of the frequency. Hemozoin has a huge, non-linear optical response for the third harmonic, which causes the blue glow."

Dr. Wiseman and his colleagues now hope to adapt well-established existing technologies like fibre-optic communications lasers
'/>"/>

Contact: Mark Shainblum
mark.shainblum@mcgill.ca
514-398-2189
McGill University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. McGill researchers link enzyme to breast cancer malignancy
2. Stanford researchers find culprit in aging muscles that heal poorly
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. Bipolar disorder relapses halved by Melbourne researchers
6. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
7. High and mighty: first common height gene identified by researchers behind obesity gene finding
8. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
9. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
10. Researchers develop long-lasting growth hormone
11. Jefferson immunology researchers halt lethal rabies infection in brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... San Jose, CA (PRWEB) August 22, 2014 ... are now offering a new teeth whitening technique. Air ... during regular cleaning appointments. , Dark teeth can be ... into two categories: external stains and internal stains. External ... Internal stains can be caused by certain medications, such ...
(Date:8/22/2014)... found that targeted automated alerts in electronic health ... patients with urinary catheters. In addition, when the ... of improvement dramatically increased. , The alerts help ... in the first place and then alert them ... not been removed within a recommended time period. ...
(Date:8/22/2014)... August 22, 2014 Natural Clear Vision ... to restore his own vision from legally blind to perfect ... an investigative review. , “There is a huge portion ... for everyday function, and most people just think that’s the ... eye surgery that can be pretty risky at times,” reports ...
(Date:8/22/2014)... found in the circulating free tumor DNA (ctDNA) from ... patients correlates well with the EGFR mutations from patient-matched ... therapy is approved for EGFR activating mutation positive patients ... status is with DNA derived directly from tumor tissue, ... abundant and less invasive source of tumor DNA may ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 Testosterone ... filed in U.S. courts on behalf of men ... their use of prescription low testosterone therapies, Bernstein ... new claim was filed against Pfizer Inc. on ... suffered life-threatening heart issues due to his use ...
Breaking Medicine News(10 mins):Health News:Japantown Dental Introduces Air Polishing 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 3Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2Health News:High concordance between EGFR mutations from circulating-free tumor DNA and tumor tissue in non-small cell lung cancer 2Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 2Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 3Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 4
... than those that are not. A new study says ... as celiac disease”// ,CD, also known as celiac ... to result from the activation of both a cell-mediated ... glutens (prolamins and glutenins) found in wheat, barley, rye, ...
... Chemistry and Industry magazine says that tropical plants imported ... dengue and other related illnesses. // ,The Asian ... and this species was detected in the Netherlands leading ... These mosquitoes were detected in imported bamboo in a ...
... dengue fever vaccine full of promise is being tried in ... the GlaxoSmithKline vaccine //have been completed in the US and ... finished by the end of next year, Dr. Hans L. ... interest in making the vaccine available fast, given that this ...
... with anti-TNF agents (etanercept) and chemotherapy drug methotrexate ... treatment of Rheumatoid Arthritis.// Furthermore, the progression of ... over three quarters of patients. The chronic nature ... for prevention of long-term joint damage in addition ...
... Aurobindo Pharma Ltd has announced that U.S. Food ... capsules USP 250 mg & 500 mg.// ... of bacterial infections such as bronchitis, tonsillitis, ear ... has achieved another major milestone by obtaining the ...
... conducted on nearly 50 nursery school children has revealed ... it on to their children as well, //resulting in ... were considerably higher amongst the group of children studied. ... children were greater than twice the normal levels in ...
Cached Medicine News:Health News:Breastfeeding: A Boon For Cealiac Disease 2Health News:Combination Therapy With ENBREL And Methotrexate Found Effective In RA Treatment 2Health News:Children’s Stress Levels Directly Related To Maternal Job Satisfaction 2
(Date:8/22/2014)... Mich. , Aug. 22, 2014  Diplomat, ... selected as one of two winners in the ... Specialty Pharmacy Solutions, LLC. The results of the ... of Specialty Pharmacy News. Diplomat ... Diplomat University Education & Training program. Through Diplomat ...
(Date:8/22/2014)... /CNW/ - On Aug. 20, at its annual meeting ... Association (CMA) voted on and approved a delegate resolution ... cannabis. Bedrocan Cannabis Corp., a leading Canadian licensed producer ... The CMA is quite right to point ... any plant material, including medicinal cannabis. While some patients, ...
(Date:8/22/2014)... , Aug. 22, 2014  Dr. Mark Rasak ... the Diamond Lifetime Achievement Award in the field of ... of Cardiovascular Clinical Associates. Dr. Rasak has ... all major aspects of the business; overseeing the daily ... primary coronary intervention. In addition, he is an honored ...
Breaking Medicine Technology:Diplomat honored as a Top Innovator by Specialty Pharmacy News 2Bedrocan Canada Statement Regarding Canadian Medical Association Motion on Smoking Marijuana 2Dr. Mark Rasak, MD is recognized by Continental Who's Who with the Diamond Lifetime Achievement Award 2
... Slit Lamp features easy-to-use controls to help ... to a halogen bulb that gives up ... with powers of 10X and 16X, the ... accepts commercially available C-mount cameras, allowing physicians ...
... uses state-of-the-art waveform analysis and ... a 65MHz rate to obtain ... and averages nine measurements and ... fits comfortably into the hand ...
Perfect for loading small volume samples onto agarose and polyacrylamide gels....
1000 L, Bulk Recommended for 500 and 1000 L pipettes...
Medicine Products: