Navigation Links
McCullers reviews influenza, bacterial superinfections in Nature Reviews Microbiology
Date:4/17/2014

Le Bonheur Children's Hospital Pediatrician-in-Chief Jon McCullers, MD, was recently invited to submit a review in the April issue of Nature Reviews Microbiology, one of the world's foremost scientific publications. Dr. McCullers, a world-renowned infectious disease specialist, and chair of the Department of Pediatrics at the University of Tennessee Health Science Center, analyzed the epidemiology and microbiology of co-infections during the 1918, 1957 and 1968 pandemics, as well as more recent 2009 novel H1N1 pandemic.

He reviewed the co-pathogenesis of influenza viruses with bacteria in the lung. Bacterial superinfection in the lungs of those suffering from influenza is a key element that promotes severe disease and mortality.

The co-pathogenesis McCullers reviewed is characterized by complex interactions between co-infecting pathogens and the host, leading to the disruption of physical barriers, dysregulation of immune responses and delays in a return to homeostasis.

The net effect of this cascade can be the outgrowth of the pathogens, immune-mediated pathology and increased morbidity.

McCullers calls for large-scale studies involving consortia or clinical networks to unlock the next unanswered questions about co-infections and viruses in order to prevent the loss of life of a pandemic similar to the one in 1918.

"There is increasing recognition that most pneumonia is caused by co-infections rather than a single pathogen, and the most severe disease seen in influenza pandemics is mediated by co-infecting bacteria working with the virus," said McCullers. "The scientific community must help the world prepare for the next pandemic by understanding a set of key, unanswered questions that are addressed in this review."


'/>"/>

Contact: Sara Burnett
sara.burnett@lebonheur.org
901-287-6030
Le Bonheur Children's Hospital
Source:Eurekalert

Page: 1

Related medicine news :

1. Vision Without Glasses: Review Released by ReviewsGod.com
2. Survive Her Affair Reviews
3. Survive Her Affair Ebook Helps Men Handle Their Wives' Affairs Properly - abb2u.com
4. Collection of Long Island Hearing Aid Reviews from East End Hearing Makes Selecting an Audiologist and a First Hearing Aid Easier
5. 1Heart Caregiver Services Reviews Business Process and System for 2014
6. Showcase of Hearing Aid Reviews in Medford Oregon Created by Imaginears
7. Memory Supplements
8. Power Memory Formula Reviews Can Help People Maximize and Optimize Their Memorizing Power - abb2u.com
9. Los Angeles Hair Transplant Surgeon Publishes His Newest Book “Modern Hair Restoration” Which Reviews the Most Advanced Techniques of Hair Restoration
10. Best Fashion Jewelry At Low Prices For Customers from USA and Europe – Jewelry Reviews by SeeTips.com
11. Representative Rakestraw Braddock Reviews Technology in Georgia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... May 05, 2016 , ... A local study examining ... than 40 percent of participating fifth-grade students already have or are at risk ... Clinical Research in the Division of Pulmonary, Allergy and Critical Care Medicine at ...
(Date:5/5/2016)... NEW YORK (PRWEB) , ... May 05, 2016 , ... ... and swimming safety – today announced a new partnership to reach nearly 1 million ... can happen in an instant and is the leading cause of accidental death in ...
(Date:5/5/2016)... ... May 05, 2016 , ... Sun ... talk highlighting the organization’s successful Care Transitions program at the 9th ... was titled “Minimizing Costs in the Post-Acute Environment Through Effective Transitions of Care.” ...
(Date:5/5/2016)... ... , ... The 2016 Nike Soccer Camp will be directed by the 2015 ... Together they bring their winning Vandals coaching philosophy to young athletes. Programs are offered ... high school players. Session dates are as follows: , Youth Day Camp – July ...
(Date:5/5/2016)... ... May 05, 2016 , ... Talent Tech Labs (TTL) is pleased ... of National Nurses Week (May 6-12). Currently, HireNurses is a job listing ... into the Talent Tech Lab Virtual Incubation program, they will dramatically expand the functionality ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... WASHINGTON D.C. , May 4, 2016 /PRNewswire/ ... its member companies concluded a series of free ... training in global requirements for Good ... part of quality assurance which ensures that products are ... by the marketing authorization (MA) or product specification. Only ...
(Date:5/4/2016)... 4, 2016 Research ... "Global Acute Ischemic Stroke Market and Competitive ... offering.       (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ... Ischemic Stroke Market and Competitive Landscape Highlights ... Stroke pipeline products, Acute Ischemic Stroke epidemiology, ...
(Date:5/4/2016)... 4, 2016 Research ... "Global Acute lymphocytic Leukemia Market and Competitive ... offering.       (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ... Leukemia Market and Competitive Landscape Highlights 2016, ... pipeline products, Acute Lymphocytic Leukemia epidemiology, Acute ...
Breaking Medicine Technology: