Navigation Links
McCullers reviews influenza, bacterial superinfections in Nature Reviews Microbiology
Date:4/17/2014

Le Bonheur Children's Hospital Pediatrician-in-Chief Jon McCullers, MD, was recently invited to submit a review in the April issue of Nature Reviews Microbiology, one of the world's foremost scientific publications. Dr. McCullers, a world-renowned infectious disease specialist, and chair of the Department of Pediatrics at the University of Tennessee Health Science Center, analyzed the epidemiology and microbiology of co-infections during the 1918, 1957 and 1968 pandemics, as well as more recent 2009 novel H1N1 pandemic.

He reviewed the co-pathogenesis of influenza viruses with bacteria in the lung. Bacterial superinfection in the lungs of those suffering from influenza is a key element that promotes severe disease and mortality.

The co-pathogenesis McCullers reviewed is characterized by complex interactions between co-infecting pathogens and the host, leading to the disruption of physical barriers, dysregulation of immune responses and delays in a return to homeostasis.

The net effect of this cascade can be the outgrowth of the pathogens, immune-mediated pathology and increased morbidity.

McCullers calls for large-scale studies involving consortia or clinical networks to unlock the next unanswered questions about co-infections and viruses in order to prevent the loss of life of a pandemic similar to the one in 1918.

"There is increasing recognition that most pneumonia is caused by co-infections rather than a single pathogen, and the most severe disease seen in influenza pandemics is mediated by co-infecting bacteria working with the virus," said McCullers. "The scientific community must help the world prepare for the next pandemic by understanding a set of key, unanswered questions that are addressed in this review."


'/>"/>

Contact: Sara Burnett
sara.burnett@lebonheur.org
901-287-6030
Le Bonheur Children's Hospital
Source:Eurekalert

Page: 1

Related medicine news :

1. Vision Without Glasses: Review Released by ReviewsGod.com
2. Survive Her Affair Reviews
3. Survive Her Affair Ebook Helps Men Handle Their Wives' Affairs Properly - abb2u.com
4. Collection of Long Island Hearing Aid Reviews from East End Hearing Makes Selecting an Audiologist and a First Hearing Aid Easier
5. 1Heart Caregiver Services Reviews Business Process and System for 2014
6. Showcase of Hearing Aid Reviews in Medford Oregon Created by Imaginears
7. Memory Supplements
8. Power Memory Formula Reviews Can Help People Maximize and Optimize Their Memorizing Power - abb2u.com
9. Los Angeles Hair Transplant Surgeon Publishes His Newest Book “Modern Hair Restoration” Which Reviews the Most Advanced Techniques of Hair Restoration
10. Best Fashion Jewelry At Low Prices For Customers from USA and Europe – Jewelry Reviews by SeeTips.com
11. Representative Rakestraw Braddock Reviews Technology in Georgia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in ... ways they remain in the eye of the beholder, according to experts who offered ... The American Journal of Managed Care. For the full issue, click here . ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: