Navigation Links
Mayo Clinic tests novel vaccine for aggressive brain tumors
Date:10/22/2007

JACKSONVILLE, Fla. − A vaccine that has significantly increased life expectancy in early tests of patients with glioblastoma multiforme (GBM) − the most common, most aggressive form of brain cancer in adults − is now being offered through a clinical trial at Mayo Clinic in Jacksonville.

The vaccine represents a fresh and fairly simple approach to treating this cancer, says neurosurgeon Kent New, M.D., Ph.D., who will be leading the study at Mayo. About 40% of these tumors display a particular protein on their surface and the vaccine is designed to trick the patients immune system into thinking the protein is foreign in order to mount a killing response.

We are pleased to have a new and promising therapy to offer patients who want to participate in this clinical trial, says Dr. New. The results, so far, have exceeded expectations.

Earlier studies of the vaccine at the University of Texas M. D. Anderson Cancer Center and Duke University Medical Center showed that median survival for the 39 GBM patients tested increased by more than 50 percent compared to the typical outcome. Additionally, the time it took tumors to begin growing again was doubled.

Dr. New cautioned, however, that it is unknown whether the vaccine added to standard treatment (surgery followed by radiation and chemotherapy) will ultimately produce any better outcome than the standard treatment alone. By comparing standard therapy plus the vaccine to standard therapy alone, we hope to determine the true benefit of the vaccine he says.

According to the National Cancer Institute, more than 20,000 people in the U.S. will be diagnosed with a brain tumor in 2007 and almost 13,000 will die from the cancer. GBM, the most common primary brain tumor, is considered incurable; most patients die within a year of diagnosis.

Twenty or more centers nationwide will participate in the clinical trial initially, which is being sponsored by Celld
'/>"/>

Contact: Cynthia Nelson
nelson.cynthia1@mayo.edu
904-953-0464
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. How do patients benefit of clinical trials
3. Magnetic resonance angiography in clinical medicine
4. Clinical trials need to be more frank
5. AEternas acquisition of Zentaris being followed up with its new product pipeline and clinical development strategy
6. Physicians Lack Clinical Guidelines For Treating Elderly With Multiple Illnesses
7. The Growing Rise In Clinical Research Could Lead To A Compromise In Quality Of Research And Ethics
8. Clinical Comparisons Between ADHD Drugs Are Less
9. Specialized Clinics For Manipurs AIDS Patients
10. Outsourcing clinical trials to India
11. Erectile dysfunction: an early warning sign of clinically silent coronary artery disease?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... MONDAY, Sept. 1, 2014 (HealthDay News) -- You may be ... than unhealthy ones, new research suggests. The study included ... newly designed weight-loss program meant to change how people react ... group of five overweight and obese people who weren,t in ... the start of the study and again six months later. ...
(Date:9/1/2014)... September 01, 2014 Currently, scientists ... effective treatments for Alzheimer's disease (AD), which reflects ... exist regarding the diagnosis of the disease, especially ... of appropriate diagnostic tests. In 2014, after ... greatest breakthroughs in the medicine world, there are ...
(Date:9/1/2014)... 2014 "Women struggle with weight gain ... changes begin as early as 15, if not earlier. ... the ups and downs of hormone related weight gain. ... healthy sizes seems to rage against the hidden and ... in her 40's begin to face menopause and related ...
(Date:9/1/2014)... Monday 1 September 2014: Daily fruit consumption cuts ... 40%, according to research presented at ESC Congress today ... from the seven year follow-up study of nearly 0.5 ... the more fruit people ate, the more their risk ... ischaemic heart disease (IHD) and stroke, is the leading ...
(Date:9/1/2014)... D.C. (PRWEB) September 01, 2014 The ... pleased to announce that Dawn Bazarko, DNP, MPH, RN, ... Fellows of the American Academy of Nursing. They will ... MBA, RN-BC, CCM, FACHE, whose induction we reported last ... October 18, 2014, during the 2014 American Academy of ...
Breaking Medicine News(10 mins):Health News:Train Your Brain to Choose Fruit Salad Over French Fries 2Health News:Early Stage Minimally Invasive Candidate AD Biomarkers Reviewed in New Study by Biopharm Reports Available at MarketPublishers.com 2Health News:Early Stage Minimally Invasive Candidate AD Biomarkers Reviewed in New Study by Biopharm Reports Available at MarketPublishers.com 3Health News:Female Hormonal Imbalances - Can’t Seem to Shed Those Extra Pounds? Discussion with Medical Expert Dr. Clairborne on Dr. Carol Francis Talk Radio Today 2Health News:Female Hormonal Imbalances - Can’t Seem to Shed Those Extra Pounds? Discussion with Medical Expert Dr. Clairborne on Dr. Carol Francis Talk Radio Today 3Health News:Fruit consumption cuts CVD risk by up to 40 percent 2Health News:Fruit consumption cuts CVD risk by up to 40 percent 3Health News:Two Additional NAHN Members to be Inducted as Fellows of the American Academy of Nursing 2Health News:Two Additional NAHN Members to be Inducted as Fellows of the American Academy of Nursing 3Health News:Two Additional NAHN Members to be Inducted as Fellows of the American Academy of Nursing 4
... researchers report , , WEDNESDAY, Oct. 31 (HealthDay News) -- Screening ... study suggests. , As a matter of fact, that might ... Dutch researchers who found that 7.2 percent of those who ... percent had cerebral aneurysms, and 1.6 had benign brain tumors. ...
... 31 The Medicare bidding,program for durable medical ... homecare infrastructure" unless Congress modifies,the program. This is ... a,congressional subcommittee today by the American Association for ... patients,standard of care, choice of provider, and access ...
... TSX, MONTREAL, Oct. 31 /PRNewswire-FirstCall/ - Haemacure ... of,its presentation at the Acumen BioFin Rodman & ... at 11:30 a.m. at the New York,Palace Hotel ... webcast the audio portion of the presentation and,post ...
... Mass., Oct. 31 Coley,Pharmaceutical Group, Inc. (Nasdaq: ... Ph.D., Coley,s President and Chief Executive Officer, plans ... Acumen BioFin Rodman &,Renshaw 9th Annual Healthcare Conference ... New York Palace Hotel. Interested parties may ...
... Tuesday, November 6 at 8:50 a.m. ET -, ... ) announced that William Iacona, Somanetics, chief financial,officer, will ... Annual,Healthcare Conference being held November 5-7, 2007 at the ... scheduled for 8:50 a.m. ET on,Tuesday, November 6, 2007, ...
... ... Information-, ... Breast Cancer Awareness Month, healthcare providers and advocacy,organizations now have ... educational, state-of-the-art Web site about,oral chemotherapy. This straightforward, credible site ...
Cached Medicine News:Health News:Brain MRIs Find Hidden Neurological Problems 2Health News:Brain MRIs Find Hidden Neurological Problems 3Health News:Medicare Bidding for Durable Medical Equipment Will Harm Small Businesses and Seniors' Access to Care, American Association for Homecare Testifies 2Health News:Medicare Bidding for Durable Medical Equipment Will Harm Small Businesses and Seniors' Access to Care, American Association for Homecare Testifies 3Health News:Haemacure announces webcast of presentation at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conferencec 2Health News:Somanetics Corporation to Present at Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 2Health News:Roche Offers Innovative Website Designed to Empower Cancer Patients 2
(Date:8/29/2014)... -- In part four of a blog series ... a strategic asset, Mary Baxter, MBA, RPh ., ... Innovation Delivery Solutions business, discusses how expanding patient access ... patients. "Every hospital pharmacist knows that filling ... in a value-based healthcare world," Baxter says. "For the ...
(Date:8/29/2014)...  Pacific Medical Data Solutions is excited to announce ... The main website, along with the site,s blog, has ... and content relevant to the medical billing industry.   ... can now better understand how PMDS products help drive ... a more visible platform about medical billing best practices. ...
(Date:8/29/2014)... DUBLIN , August 29, 2014 ... management and collaboration software has announced a major new ... services, founded by renowned pathology expert, Dr. Marius ... advance of the 26th European Congress of Pathology which ... in the ExCeL Arena, London ...
Breaking Medicine Technology:Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 2Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 4PMDS Announces New Website 2Pixcelldata Announces New Deal with Dutch Tele-Pathology Specialists eX-Path Ahead of ECP 2014 2
... Both the Marco Keratometer ... one position instruments for objectively ... II has the added feature ... presbyopic practitioner or those who ...
... Bulb Direct has been ... Internet since 1996, and we ... 100% satisfaction guarantee. Check out ... and see our discount light ...
... Bulb Direct has been ... Internet since 1996, and we ... 100% satisfaction guarantee. Check out ... and see our discount light ...
... Bulb Direct has been selling ... since 1996, and we are ... satisfaction guarantee. Check out our ... see our discount light bulbs ...
Medicine Products: