Navigation Links
Mayo Clinic study points to a possible biomarker for colon cancer in people 50 and under
Date:10/27/2007

ROCHESTER, Minn. -- An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease.

The finding may provide an early alert for younger patients with colon cancer and could prompt new research into colon cancer prevention and treatment strategies, say Mayo Clinic researchers.

The study results will be presented at 10 a.m., Saturday, Oct. 27, during the annual meeting of the American Society of Human Genetics in San Diego.

The Mayo Clinic team led by Lisa Boardman, M.D., a specialist in gastrointestinal malignancies, investigated the structures inside of cells known as telomeres, which are the caps on the ends of chromosomes that keep chromosomes from unraveling. Telomeres naturally shorten with aging and are associated with many diseases of aging, including cancer. Shortened telomeres have been found in colon cancer tumor cells, but this study links these telomeres to colon cancer.

Dr. Boardman and an interdisciplinary group of researchers examined the DNA in blood samples of 114 colon cancer patients 50 years old and younger and 98 people with no history of cancer. They found that the colon cancer patients had abnormal telomeres that were unusually short, particularly for a group of patients considered young for colon cancer: patients in the study were about 15 years younger than the average age of patients with colon cancer. In addition, colon cancer in this younger group affected men more often than women.

Colon cancer, also called colorectal cancer or bowel cancer, includes cancerous growths in the colon, rectum and appendix. Its the second leading cause of cancer death in the United States, affecting nearly 145,000 people each year. The first cases tend to appear in people in their 40s, but most patients tend to be in their mid 60s by the time they are diagnosed. <
'/>"/>

Contact: Amy Reyes
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. How do patients benefit of clinical trials
3. Magnetic resonance angiography in clinical medicine
4. Clinical trials need to be more frank
5. AEternas acquisition of Zentaris being followed up with its new product pipeline and clinical development strategy
6. Physicians Lack Clinical Guidelines For Treating Elderly With Multiple Illnesses
7. The Growing Rise In Clinical Research Could Lead To A Compromise In Quality Of Research And Ethics
8. Clinical Comparisons Between ADHD Drugs Are Less
9. Specialized Clinics For Manipurs AIDS Patients
10. Outsourcing clinical trials to India
11. Erectile dysfunction: an early warning sign of clinically silent coronary artery disease?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2009)The MAMA campaign is a collaborative effort by the National Association of Certified Professional Midwives (NACPM), Midwives Alliance of North America (MANA), Citizens for Midwifery (CfM), Internation
(Date:12/4/2009)NEW YORK, Dec. 4 Thousands of KPMG LLP employees came together in more than 90 offices nationwide today, to participate in a community service event which combines the audit, tax and advisory firm,s
(Date:12/4/2009)SCOTTSDALE, Ariz., Dec. 4 Healthcare Trust of America, Inc. ("HTA"), a self-managed, non-traded, real estate investment trust, announced the execution of a purchase and sale agreement to acquire a th
(Date:12/4/2009)WASHINGTON, Dec. 4 While Congress debates whether health care reform would control health care costs, Leapfrog,s purchaser members point to 45 hospitals that lead through example -- delivering the be
(Date:12/4/2009)Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called "Twist" may be the proverbial red flag that can accuratel
Breaking Medicine News(10 mins):Health News:AquaNatal Birth Center Gives Away a Waterbirth Package to Celebrate the Successful MAMA Campaign 2Health News:AquaNatal Birth Center Gives Away a Waterbirth Package to Celebrate the Successful MAMA Campaign 3Health News:AquaNatal Birth Center Gives Away a Waterbirth Package to Celebrate the Successful MAMA Campaign 4Health News:KPMG Employees Provide 'Holiday Bear Hugs' and Books in Firmwide Service Day for Children 2Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 92,500 Square Foot Medical Office Portfolio Located in Texas and Indiana 2Health News:The Leapfrog Group Releases Its 2009 Top Hospitals List 2Health News:The Leapfrog Group Releases Its 2009 Top Hospitals List 3Health News:Potential new 'twist' in breast cancer detection 2Health News:Potential new 'twist' in breast cancer detection 3
...ill Discuss Best Practices in HCV and HIV Drug-Dis...l Drug Development Decision ... Pharsight,Corporation (Nasdaq: PHST ), a leading..., vice president and,lead scientist, Strategic Con...
...Understanding Not Confusion, FOLSOM, Calif., Feb...., CEO of California Walnut Commission: Given the s...r consumer understanding of healthy,food choices i...be confusing, our research says that people want m...
...or Health Solutions study finds anxiety over finan... a key issue in the upcoming ...erican consumers want more from,their health care ...r access to emerging innovations such as retail,cl...
... and techniques discussed at surgeons, conference,...n surgery patients are getting back on their feet ... The introduction of tissue graft products, bone a...han 1,000 foot,and ankle surgeons are learning abo...
..., Feb. 20 Varian Medical,Systems (NYSE: VAR ) is...,its revolutionary RapidArc(TM) radiotherapy techn...s. These symposia offer clinicians the opportunity...er than is possible with conventional IMRT or heli...
...ael, February 20 012,Smile.Communications (Nasdaq... fourth quarter results on Tuesday , February 26, ..., Management will host an interactive,teleconferen...800-994-4498 from within the U.S. or 1-888-604-583...
Other Medicine News:Health News:Pharsight to Host Webinar on Hepatitis C Virus (HCV) and HIV Drug-Disease Modeling 2Health News:Walnuts Rank High on New Nutrition Scales 2Health News:Walnuts Rank High on New Nutrition Scales 3Health News:Groundbreaking Deloitte Survey Reveals Many U.S. Consumers Want Major Changes in Health Care Design, Delivery 2Health News:Groundbreaking Deloitte Survey Reveals Many U.S. Consumers Want Major Changes in Health Care Design, Delivery 3Health News:Groundbreaking Deloitte Survey Reveals Many U.S. Consumers Want Major Changes in Health Care Design, Delivery 4Health News:Achilles Tendon Surgery Advances Speed Recovery 2Health News:Varian Medical Systems Announces Symposia on RapidArc Technology for Faster, More Precise Radiotherapy Treatments 2Health News:Varian Medical Systems Announces Symposia on RapidArc Technology for Faster, More Precise Radiotherapy Treatments 3Health News:012 Smile.Communication's Fourth Quarter Earnings Release and Conference Call Scheduled for February 26, 2008 2Health News:012 Smile.Communication's Fourth Quarter Earnings Release and Conference Call Scheduled for February 26, 2008 3
(Date:12/4/2009)FREMONT, Calif., Dec. 4 Vermillion, Inc. (VRML) (Pink Sheets: VRMLQ) announced that on December 3, 2009, it filed its First Amended Plan of Reorganization and related amended Disclosure Statement wit
(Date:12/4/2009)EMERYVILLE, Calif., Dec. 4 Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced that it will host an investor teleconference and webcast. Principal investigators will discuss the data present
(Date:12/4/2009)STREAMWOOD, Ill., Dec. 4 Shared Imaging, LLC, an independent provider of CT, MRI and PET/CT systems and service programs for hospitals and healthcare providers, is excited to announce it has received
Breaking Medicine Technology:Vermillion Files Amended Plan of Reorganization and Exchanges Debt 2Vermillion Files Amended Plan of Reorganization and Exchanges Debt 3Onyx Pharmaceuticals to Host American Society of Hematology (ASH) Investor Teleconference 2Shared Imaging Earns The Joint Commission's Accreditation for Ambulatory Health Care 2New NIST trace explosives standard slated for homeland security duty 9836 1New NIST trace explosives standard slated for homeland security duty 9836 2A L L 3A Bishops Must Choose Between Christ Centered Care and Obamacare 56579 1A L L 3A Bishops Must Choose Between Christ Centered Care and Obamacare 56579 2Leading Anti Aging Prescription RENOVA 28R 29 Continues To Deliver Maximum Results 56574 1Leading Anti Aging Prescription RENOVA 28R 29 Continues To Deliver Maximum Results 56574 2Leading Anti Aging Prescription RENOVA 28R 29 Continues To Deliver Maximum Results 56574 3
... Bard mesh has become the standard against which a... by Dr. Irving Lichtenstein when he first develope... Lichtenstein describes Bard mesh as "a safe and i...nia repair. As an abundance of literature indicate...
...polypropylene mesh specifically designed for lapar...sses the critical issues associated with laparosco...imum visibility, enhanced maneuverability and reta...car.,Visilex mesh is the culmination of input and...
...dimensional, anatomically formed prosthesis for us...sh has been designed based on careful and precise ...ult is a truly unique prosthesis for laparoscopic ...cted of Bard mesh, knitted polypropylene monofilam...
...constructed of a double layer of monofilament poly... pocket, which is used to guide the patch into pro...otected "memory recoil ring". This ring allows the...g placement.,In addition to repairing the existin...
Medicine Products: