Navigation Links
Mayo Clinic study indicates medication for ADHD may help student outcomes

ROCHESTER, Minn. -- In an 18-year-study on attention-deficit hyperactivity disorder (ADHD), Mayo Clinic researchers found that treatment with prescription stimulants is associated with improved long-term academic success of children with ADHD. The Mayo Clinic results are the first population-based data to show stimulant drug therapy helps improve long-term school outcomes.

A related Mayo Clinic study reveals that compared to children without AD/HD, children with ADHD are at risk for poor long-term school outcomes such as low achievement in reading, absenteeism, repeating a grade, and dropping out of school. Both studies appear in the current edition of the Journal of Development & Behavioral Pediatrics, (

Nearly 2 million children, or approximately 3 percent to 5 percent of young children in the United States, have ADHD. This disorder affects a childs ability to focus, concentrate and control impulsive behavior ( This disorder is so common that most school classrooms have at least one child with clinically-diagnosed ADHD.

In this study, treatment with stimulant medication during childhood was associated with more favorable long-term school outcomes, explains William Barbaresi, M.D., Mayo Clinic pediatrician and lead author of the reports.

Significance of the Mayo Clinic Studies

The two Mayo Clinic studies are the first population-based, long-term studies to investigate links between ADHD, school performance and factors that modify long-term school performance of children with ADHD. Researchers followed the children from the time they were born for, on average, 18 years. Of the more than 5,000 children evaluated, 370 (277 boys and 93 girls) were identified as having ADHD. Researchers matched them by age and gender to 740 children who did not meet the research criteria for having AD/HD. In addition to medical stimulants such as methylphenidate, also called Ritalin, the study examined the effects on school outcomes of maternal age, socioeconomic background, and special education services the students received.

School Outcome Results At a Glance

The children treated with stimulants typically began taking medication in elementary school and received it for nearly three years -- on average, for 30.4 months. Results indicate:

  • Gender: Girls and boys with untreated ADHD were equally vulnerable to poor school outcomes -- and girls may be at risk for being under-identified as having ADHD, and therefore undertreated.

  • Reading: By age 13, on average, stimulant dose was modestly correlated with improved reading achievement scores.

  • Absenteeism: Both treatment with stimulants and longer duration of medication were associated with decreased absenteeism.

  • Grade Retention: Children with A/HD who were treated with stimulants were 1.8 times less likely to be retained a grade than children with ADHD who were not treated.

Implications for Parents and Caregivers

Dr. Barbaresi believes that both studies provide the first solid evidence of the long-term negative academic performance associated with untreated ADHD -- as well as evidence for the best way to manage this problem. Dr. Barbaresi says, The finding that treatment with stimulant medications is associated with long-term improvement in school outcomes is significant. Previously, there was evidence that treatment with stimulant medications improved short-term academic performance, but there was no good evidence that long-term outcomes are better with stimulant treatment. Our data can guide clinicians in their efforts to help children with ADHD succeed in school.

About the Studies

The Mayo Clinic team had a unique ability to identify groups of children with and without ADHD. Mayo Clinic has maintained a comprehensive communitywide medical records database since 1935, and researchers had access to all conditions, diagnoses and treatments the children received. In addition, Mayo obtained a research agreement with Independent School District #535, Rochester, Minn., including public and private schools, to access non-identifiable school records of all children born in Rochester between Jan. 1, 1976 and Dec. 31, 1982. This enabled researchers to correlate school performance of both children with and without ADHD in terms of medical conditions, maternal age, socioeconomic status and special education efforts.


Contact: Amy Tieder
Mayo Clinic

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. How do patients benefit of clinical trials
3. Magnetic resonance angiography in clinical medicine
4. Clinical trials need to be more frank
5. AEternas acquisition of Zentaris being followed up with its new product pipeline and clinical development strategy
6. Physicians Lack Clinical Guidelines For Treating Elderly With Multiple Illnesses
7. The Growing Rise In Clinical Research Could Lead To A Compromise In Quality Of Research And Ethics
8. Clinical Comparisons Between ADHD Drugs Are Less
9. Specialized Clinics For Manipurs AIDS Patients
10. Outsourcing clinical trials to India
11. Erectile dysfunction: an early warning sign of clinically silent coronary artery disease?
Post Your Comments:
(Date:12/1/2015)... , ... December 01, 2015 , ... Califia Farms ... announced that its iconic bottle has won top honors in Beverage World Magazine’s Global ... Company also announced that it has been selected as a 2015 U.S.A. Taste Champion ...
(Date:12/1/2015)... MD (PRWEB) , ... December 01, 2015 , ... ... salmon identification tests to continue the expansion of the company’s growing product line ... – for Chinook (Oncorhynchus tshawytscha) and Sockeye (Oncorhynchus nerka) – allow InstantLabs to ...
(Date:12/1/2015)... ... December 01, 2015 , ... The ... been lifted as IMAGE Information Systems launches MED-TAB™ -- the world’s first portable ... Meeting from November 29 to December 4, 2015. , MED-TAB is expected ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... is everything. That is why Hollister Incorporated has launched the VaPro Plus Pocket™ ... next product in the VaPro touch free catheter portfolio,” said Michael Gresavage, Vice ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... today announced it has been awarded a fixed price per sprint agile development ... contract, valued at $34 million over five years, provides software engineering, infrastructure, as ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... 1, 2015 --> ... Drugs Market by Type of Drug (Monoclonal Antibodies, Interferon-Alpha, Interleukins, ... and Pipeline Analysis - Global Forecast to 2020", published by ... USD 73,529.2 Million by 2020 from USD 40,281.6 Million in ... Browse 37 market data ...
(Date:12/1/2015)... BANGALORE, India and PITTSBURGH ... TASE: MYL) today announced that it expects to be ... developing country markets funded by international donors, TLE400 (Tenofovir ... Efavirenz 400 mg) for $99 per patient, per year. ... to develop TLE400. The significantly reduced price could generate ...
(Date:12/1/2015)... , Dec. 1, 2015  AccuTEC Blades, a ... new corporate logo and brand identity program. The ... and engineering of bladed products where "the edge ... --> Serving manufacturers and distributors ... auto glass equipment, AccuTEC,s product lines include those ...
Breaking Medicine Technology: