Navigation Links
Mayo Clinic study: multiple surgeries and anesthesia exposure
Date:10/2/2011

ROCHESTER, Minn. -- Every year millions of babies and toddlers receive general anesthesia for procedures ranging from hernia repair to ear surgery. Now, researchers at Mayo Clinic in Rochester have found a link among children undergoing multiple surgeries requiring general anesthesia before age 2 and learning disabilities later in childhood.

The study, which will be published in the November 2011 issue of Pediatrics (published online Oct. 3), was conducted with existing data of 5,357 children from the Rochester Epidemiology Project and examined the medical and educational records of 1,050 children born between 1976 and 1982 in a single school district in Rochester.

"After removing factors related to existing health issues, we found that children exposed more than once to anesthesia and surgery prior to age 2 were approximately three times as likely to develop problems related to speech and language when compared to children who never underwent surgeries at that young age," says David Warner, M.D., Mayo Clinic anesthesiologist and co-author of the study.

Among the 5,357 children in the cohort, 350 underwent surgeries with general anesthesia before their second birthday and were matched with 700 children who did not undergo a procedure with anesthesia. Of those exposed to anesthesia, 286 experienced only one surgery and 64 had more than one. Among those children who had multiple surgeries before age 2, 36.6 percent developed a learning disability later in life. Of those with just one surgery, 23.6 percent developed a learning disability, which compares to 21.2 percent of the children who developed learning disabilities but never had surgery or anesthesia before age 2. However, researchers saw no increase in behavior disorders among children with multiple surgeries.

"Our advice to parents considering surgery for a child under age 2 is to speak with your child's physician," says Randall Flick, M.D., Mayo Clinic pediatric anesthesiologist and lead author of the study. "In general, this study should not alter decision-making related to surgery in young children. We do not yet have sufficient information to prompt a change in practice and want to avoid problems that may occur as a result of delaying needed procedures. For example, delaying ear surgery for children with repeated ear infections might cause hearing problems that could create learning difficulties later in school."

This study, funded by the U.S. Food and Drug Administration, examines the same population data used in a 2009 study by Mayo Clinic researchers, which reviewed records for children under age 4 and was published in the medical journal Anesthesiology.

The 2009 Mayo Clinic study was the first complete study in humans to suggest that exposure of children to anesthesia might affect development of the brain. Several previous studies suggested that anesthetic drugs might cause abnormalities in the brains of young animals. The study released today is significant because it examines children experiencing anesthesia and surgeries under age 2 and removes factors associated with existing health issues.


'/>"/>
Contact: Kelley Luckstein
newsburea@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Cleveland Clinic to establish chair for preventive cardiology from Cleveland Foundation
2. European Journal of Heart Failure publishes new randomized controlled clinical study of RESPeRATE
3. Non-verbal clues guide doctor-patient relationships, clinical judgments, U-M study finds
4. Abiraterone acetate improves fatigue in prostate cancer patients, says international clinical trial
5. TGen-Virginia G. Piper Cancer Center launches clinical trial for drug to treat lung cancer
6. John Theurer Cancer Center among first clinical trial sites to join landmark MMRF study
7. New report on creating clinical public use microdata files
8. Cleveland Clinic researchers awarded NIH grant to study concussion-identifying blood test
9. Mayo Clinic teams with glowing cats against AIDS, other diseases
10. Whole-parasite malaria vaccine shows promise in University of Maryland School of Medicine clinical trial
11. Aerobic exercise may reduce the risk of dementia, Mayo Clinic researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... 2016 , ... The law firm of Morrow, Morrow, Ryan & Bassett is ... these scholarships is to encourage applicants to pursue a degree in their field of ... parishes. , “We have available jobs in St. Landry and Evangeline Parishes that ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... — 1:30 p.m. – 3:00 p.m. EST, http://www.fdanews.com/fixeddosecombination ... cycle of pharmaceutical products, garnering increased attention from all stakeholders in the development ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... announced that nominations have closed for the ISE Southeast Awards 2016. Finalists and ... announced at the ISE® Southeast Executive Forum and Awards Gala on March 15, ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fisher House Foundation Chairman and CEO Kenneth Fisher ... Military Support Alliance president Scott Bensing, and Peggy Kearns Director, VA Southern Nevada Healthcare ... System. This will be the first Fisher House in Nevada, and will provide ...
(Date:2/12/2016)... ... February 12, 2016 , ... Erlanger Agency has announced a new partnership in ... latest campaign focuses on the fight against breast cancer, fundraising for a local woman ... here . , Carmen is a loving single mother of two boys who also ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Stem cells are primitive cells found in all multi-cellular ... to differentiate into mature cell types Stem cells are ... embryonic stem cells were derived from embryos in 1981, ... culturing of embryonic stem cells from non-human primates occurred ... As a result of these discoveries, stem cells can ...
(Date:2/11/2016)... 2016  Kindred Biosciences, Inc. (NASDAQ: KIN ), ... lives of pets, today announced the submission to FDA ... Drug Application (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive ... Zimeta for the control of pyrexia (fever) in horses ... --> --> The Chemistry, Manufacturing, and ...
(Date:2/11/2016)...   Health 2.0 , the premiere showcase and ... today " 10 Year Global Retrospective ", a platform ... past ten years.   --> ... has served as the preeminent thought-leader in the health ... technologies, companies, innovators, and patient-activists through an array of ...
Breaking Medicine Technology: