Navigation Links
Mayo Clinic researchers identify enzyme involved in deadly brain tumors
Date:1/17/2013

/p>

"Our results show that KLK6 functions like a hormone, activating a signaling cascade within the cell that promotes tumor cell survival," Dr. Scarisbrick says. "The higher the level of the enzyme, the more resistant the tumors are to conventional therapies."

The study is the latest step in Dr. Scarisbrick's investigations of KLK6 in nervous system cells known as astrocytes. Glioblastomas arise from astrocytes that have grown out of control. Her lab has shown that KLK6 also plays a role in the perseverance of inflammatory immune cells that occur in multiple sclerosis and in aberrant survival of T-lymphocyte leukemia cell lines.

"Our findings in glioma affirm KLK6 as part of a fundamental physiological mechanism that's relevant to multiple diseases and have important implications for understanding principles of tissue regeneration," she says. "Targeting KLK6 signaling may be a key to the development of treatments for pathologies in which it's necessary to intervene to regulate cell survival and tissue regeneration in a therapeutic fashion. Ultimately, we might be able to harness the power of KLK6 for the repair of damaged organs."


'/>"/>

Contact: Bryan Anderson
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
2. First targeted nanomedicine to enter human clinical studies
3. Clinical insight improves treatment with new lung cancer drug
4. Clinical news alert from the American Academy of Orthopaedic Surgeons
5. Mayo Clinic launches whole genome breast cancer study
6. Mayo Clinic offers newly approved treatment for acid reflux disease
7. NYU Langone experts present research, clinical advances at neurosurgeons meeting
8. Mayo Clinic breast cancer study finds new type of mutation
9. Kroenke honored for outstanding contributions in clinical research training
10. Awards celebrate clinical research that can improve health and alleviate suffering
11. Association for Psychological Science, SAGE launch Clinical Psychological Science
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... IBISWorld estimates that revenue for the ... rate of 28.7% to $1.0 billion in the five years ... and 2008, no new cell therapy products were introduced, according ... during that period. In the years since, however, the Food ... factor contributed to the industry's fast growth during the five ...
(Date:5/25/2013)... Virginia (PRWEB) May 25, 2013 Superior ... that relieves pain in seconds for arthritis, tendinitis and ... in alternative pain relief products announced a magnetic ... The magnetic bracelet for pain relief is demonstrated at ... pain uses 5400 Gauss magnets and has customers often ...
(Date:5/25/2013)... AdvantaClean of Pikes Peak recently opened and ... healthy home and business in Colorado Springs and surrounding ... inspections, mold testing, mold removal , air ... , With over 120 offices nationwide, AdvantaClean is a ... full suite of services for commercial, institutional, and governmental ...
(Date:5/24/2013)... myMEDholiday.com, a popular medical tourism portal which includes an ... travel destinations in Asia, has added a helpful and ... safe and successful trip for anyone planning a healthcare ... cost-savings, how to find the appropriate doctors and facilities, ... essential advice. , A top-level marketing representative at the ...
(Date:5/24/2013)... Atlanta, GA (PRWEB) May 24, 2013 Before you ... a cup of coffee with Kathie Lee Gifford and Hoda Kotb ... http://www.digitwirl.com , will show cool tech ideas to Kathie Lee and ... Kyodo America honors our brave men and women in the military ... get ready for the BBQ, spend time with friends and family ...
Breaking Medicine News(10 mins):Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 2Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 3Health News:Magnetic bracelet relieves pain in seconds announces Superior Magnetics 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 3Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 4Health News:myMEDholiday.com Introduces International Patient Guide to Assist People Planning Treatment Abroad 2Health News:LawnBott® Visits the Today Show with Kathie Lee and Hoda 2
... the time in emergency rooms , , TUESDAY, Dec. 18 (HealthDay ... someone is having a heart attack, they are mistaken 9.2 ... that minutes matter with these patients and doctors have to ... say researchers from the Minneapolis Heart Institute Foundation. , "Our ...
... three and older in the United States would carry ... the 2008 University of Louisville Grawemeyer Award in Education. ... nations young children, fill a gap for working families, ... boost the economy, award winners Edward Zigler, Walter Gilliam ...
... led by Mayo Clinic have designed a technique that uses ... cells that spread from primary tumors to other parts of ... shows that this technology could be the basis for a ... appeared in the Dec. 9 online issue of Nature Medicine. ...
... inexpensive infection control measures, hospitals around the world could prevent ... TB), according to a new study in The Lancet by ... Wings for its ability to spread and kill rapidly, XDR ... identified in all regions of the world, including the United ...
... for patients with spinal cord injuries can stimulate ... compensatory changes in the brain, say Canadian researchers. ... function and the ability to walk. , A ... the remarkable benefits of rehabilitation training after a ...
... remains America,s No. 1 killer, AHA says , , TUESDAY, ... death rates in the United States are declining, the ... the nation, according to the American Heart Association. , ... for many people, according to the American Heart Association,s ...
Cached Medicine News:Health News:Diagnosis of Heart Attack Can Be Wrong 2Health News:Researchers train the immune system to deliver virus that destroys cancer in lab models 2Health News:Researchers train the immune system to deliver virus that destroys cancer in lab models 3Health News:Simple strategy could prevent half of deadly tuberculosis infections 2Health News:Intensive training post-spinal cord injury can stimulate repair in brain and spinal cord 2Health News:U.S. Heart Disease Death Rates Falling 2Health News:U.S. Heart Disease Death Rates Falling 3
(Date:5/23/2013)... JERUSALEM , May 23, 2013  Hadasit Bio-Holdings ... portfolio of biotech companies, based on intellectual property ... Israel ,s foremost medical research center, ... Neurosciences Ltd., received significant funding from the Israeli ... Chief Scientist (OCS) to support product development and ...
(Date:5/23/2013)... -- Texas, premier physician associations today announced the establishment of ... need to provide demonstrably better and more efficient patient ... "I am confident the Physician Services Organization for ... Stephen L. Brotherton , MD, president of the ... doctors are determined to make health care better and ...
(Date:5/23/2013)... , May 23, 2013  Net Medical Xpress ... telemedicine market, announced today the company has signed a ... staffing company based in Huntsville, AL ... specializes in the staffing and recruitment of telemedicine physicians. ... of the final agreement, which is expected by June ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
... , , , , WALTHAM, Mass., Dec. ... and advisory firms for pharmaceutical and healthcare issues, finds that ... efficacy and side-effect profile, are cited most frequently by surveyed ... non-small-cell lung cancer treatment in Germany, France, Italy, Spain and ...
... HUNTINGTON BEACH, California and AMSTERDAM, December 17 ,Agendia, a ... US Food and Drug Administration (FDA) cleared its MammaPrint ... only FDA-cleared,breast cancer recurrence test available to patients and ... four clearances for MammaPrint, covering,all aspects of this important ...
Cached Medicine Technology:Surveyed European Oncologists Cite Cost Most Frequently as the Factor Preventing Their Use of Avastin for Non-Small-Cell Lung Cancer 2Surveyed European Oncologists Cite Cost Most Frequently as the Factor Preventing Their Use of Avastin for Non-Small-Cell Lung Cancer 3FDA Broadens Clearance for Agendia's MammaPrint(R) 2
Circular Spine Retractor System for microsurgical interventions in the lumbar and cervical spine region....
... also known as BMP-7, is a member of ... Bone Morphogenetic Proteins. OP-1 Implant is known to ... mature skeletal systems. The FDA approved OP-1 Implant ... 2001. OP-1 Implant is now available across the ...
... Connect allografts are dense ... anterior cortical face providing structural ... for rapid healing. These allografts ... Non-Lordotic designs. Connect allografts are ...
... maxillo-facial and cranial surgery are characterized by ... for the most varied of applications. Tailor-made ... that the system is easy to implement ... from titanium. Specially designed instruments for drilling, ...
Medicine Products: