Navigation Links
Mayo Clinic researchers find common gene disorder doubles risk of lung cancer, even among nonsmokers
Date:5/26/2008

er among patients with COPD may be a result of lung tissue damage from emphysema, or chronic infection or inflammation of the lungs, or both," she says.

Individuals who are 1ATD carriers should have lung function checked on a routine basis and should avoid potential lung carcinogens. "We found people who carry these genes are more vulnerable to carcinogen-containing tobacco smoke, even secondhand smoke, than noncarriers," says Dr. Yang.

In this study, a team of 12 researchers looked at three different groups: 1,443 patients with lung cancer treated at Mayo Clinic from 1997 to 2003; a control group of 797 residents in the community; and a second control group of 902 siblings of the lung cancer patients. They found that:

The 1ATD carrier rate among 1,443 genotyped patients with lung cancer was 13.4 percent, compared to 7.8 percent among unrelated control participants.

All 1ATD gene carriers were at a similarly greater risk of developing lung cancer, regardless of smoking status. Those who had never smoked were at a 2.2-fold higher risk; light smokers had a twofold greater risk; and moderate to heavy smokers had a 2.3-fold increased risk. Although there's no absolute definition, less than 20 pack-years of smoking cigarettes is defined as light; more than 40 pack-years as heavy. A pack-year is the number of packs of cigarettes smoked per day multiplied by the number of years the person has smoked.

A history of COPD increased lung cancer risk significantly for light, moderate and heavy smokers, but affected those who had never smoked the most X an almost sixfold increased risk.

Increased lung cancer risk among 1ATD carriers is independent of a family history of lung or other cancers.

The estimated attributable risk for 1ATD carriers in this study among those who never smoked and among heavy smokers was 11 percent to 12 percent, suggesting that the genetic disorder might explain a significant proportion
'/>"/>

Contact: Traci Klein
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Bioniche Presents Pre-Clinical Research at Two International Conferences
2. Unlocking the promise of clinical and translational science
3. The Oregon Clinic Extends Patient Care Services Across Metro Portland with Time Warner Telecoms Metro Ethernet Service
4. China Biologic Products Announces Approval for the Relocation of Fang Cheng Plasma Collection Station and for the Procurement of Excess Clinical Plasma
5. CME Publication Gives Clinicians a Leg Up in Treating Disorders of the Lower Extremities
6. New Anticoagulation Management Software Helps Clinics Enhance Efficiency and Improve Patient Safety
7. Mayo Clinic Research Shows U.S. Intensive Care Units Prevention of Pneumonia in Critically-ill Patients Generally Strong; Identifies Area of Improvement
8. Rochester Coalition and Mayo Clinic Challenge Railroads Contention That Hazmat Rail Shipments Pose no Risk
9. Forty-Two Free Clinics Across State Share $1 Million in Grants From Blue Cross Blue Shield of Michigan
10. Clinical Solutions Subscribes to NetSuite for Global Healing of Disparate Operations
11. Shared Health(R) and Novo Innovations Partner for Improved Information-Sharing of Clinical Health Records
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... 17, 2015 From the day Dr. Todd ... Texas non-profit organization has empowered young people to create meaningful ... bring fresh water and the Gospel to all of ... Between March 17 and 27, students, faculty and staff raised ... with fresh water and the Good News of Jesus. ...
(Date:4/17/2015)... Enthusiasts of gourmet cuisine and beverages will be ... The event will be held in the heart of downtown ... NW, Grand Rapids, MI 49503) and will feature wine personalities ... are encouraged to savor the food and beverage pairings while ... event will feature seven chefs, including:, ...
(Date:4/17/2015)... 2015 Testosterone treatment lawsuits ( ... prescription medications increases the likelihood that a man ... life-threatening cardiovascular event continue to mount in a ... District of Illinois. According to an updated Statistics ... Multidistrict Litigation (JPML) on April 15th, 1,382 cases ...
(Date:4/17/2015)... Francisco, CA (PRWEB) April 17, 2015 The American ... House event and Free Application Day on April 29. The event ... ACTCM Pioneer Square, located at 555 DeHaro St. in San Francisco, ... 11 a.m. – Check in at the DeHaro campus (room F), ... – Tour of campus, Noon – Light lunch with current students, ...
(Date:4/17/2015)... North Carolina (PRWEB) April 17, 2015 ... Family Dental Care has spent the last four ... dental care, performing procedures ranging from general cleanings to ... host a grand opening at their new office in ... the same services as their Concord office, including denture ...
Breaking Medicine News(10 mins):Health News:The Last Well and Liberty U’s TEN Initiative raises $21,000 to Bring Fresh Water & The Gospel to 7,000 Liberians 2Health News:Children’s Leukemia Foundation of Michigan Presents 3rd Annual CRUSH Grand Rapids 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 3Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 4Health News:American College of Traditional Chinese Medicine Hosts Open House 2
... LAKE CITY, Oct. 22 /PRNewswire/, WHAT: In response to the ... Children,s Miracle Network hospitals are on call to answer ... (MRSA), a form of ... antibiotics, and other pediatric medical questions you have., ...
... American Red Cross encourages evacuees to register on Safe ... continue to rage across,Southern California, forcing thousands to evacuate ... help for those who may feel confused,and anxious about ... The Red Cross urges all those who have evacuated ...
... ... Double Adjusted EBITDA in Fourth Quarter of ... 2007, ... of health, beauty, vision, and,pharmacy products, today announced its financial results for the third,quarter ...
... Says VA Refuses to Act in Good Faith ... Oct. 22 The American Federation,of Government Employees ... Florida/South Georgia Veterans Health System (NF/SGVHS), today,criticized the ... act in,good faith with its employees by failing ...
... world,s adults are obese, study finds , , MONDAY, Oct. 22 ... percent of women are now overweight, and 24 percent of ... who looked at data from 63 countries. , The study ... 18-80 (average age 48), living on five continents. All of ...
... of each extraordinary gift to benefit St. Jude ... Children,s Research Hospital -, ... has created five exclusive, over-the-top luxury gifts available for,purchase beginning October ... Jude Children,s Research Hospital. Each extravagant gift was inspired by ...
Cached Medicine News:Health News:Children's Miracle Network Hospital Doctors On Call to Answer Questions About MRSA Infection 2Health News:Southern California Wildfires Continue to Threaten Residential Areas 2Health News:Southern California Wildfires Continue to Threaten Residential Areas 3Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 2Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 3Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 4Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 5Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 6Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 7Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 8Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 9Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 10Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 11Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 12Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 13Health News:drugstore.com inc. Reports Record Gross Margins and Bottom Line Results for the Third Quarter of 2007 14Health News:Mismanagement at North Florida/South Georgia Veterans Health System Results in Chronic Staff Shortages, Budget Issues 2Health News:Overweight Now a Global Problem 2Health News:Saks Fifth Avenue Unveils Five Magical Holiday Gifts 2Health News:Saks Fifth Avenue Unveils Five Magical Holiday Gifts 3
(Date:4/17/2015)... , April 17, 2015 ... EGFR mutation   is a viable alternative to tumour biopsy ... testing in all patients with advanced NSCLC   ... effectiveness of plasma circulating tumour DNA (ctDNA) testing for epidermal ... with advanced non-small cell lung cancer (NSCLC) in clinical practice. ...
(Date:4/17/2015)... Research and Markets ( http://www.researchandmarkets.com/research/5hkm2f/medical_oxygen ) ... Systems - Global Strategic Business Report" report to ... markets for Medical Oxygen Systems in US$ Thousands by ... Cylinders & Regulators, and Oxygen Conserving Devices. The report ... Canada , Japan , ...
(Date:4/17/2015)... Apr. 16, 2015 Research and Markets ... "Corporate Reputation of Pharma in 2014 - a ... report to their offering. This independent study, ... patient groups with an interest in diabetes on the ... the pharma industry as a whole) in 2014. The ...
Breaking Medicine Technology:"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 2"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 3"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 4Medical Oxygen Systems - 2015 Global Strategic Business Report Featuring Leading Players, Caire, Invacare & Philips Respironics 2Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 2Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 3Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 4Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 5
... YORK, Nov. 4, 2010 Reportlinker.com ... report is available in its catalogue: ... Cancer Overview - Metastatic gastrointestinal cancers ... to a lack of approved drugs ...
... YORK, Nov. 4 Reportlinker.com announces that ... in its catalogue: Stakeholder ... - Opportunities in Brazil, Mexico and Argentina ... IntroductionOver the past decade, vaccines ...
Cached Medicine Technology:Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 2Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 3Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 4Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 5Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 6Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 7Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 8Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 9Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 10Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 11Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 12Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 13Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 14Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 15Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 16Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs 17Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 2Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 3Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 4Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 5Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 6Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 7Stakeholder Opinions: Vaccines in emerging markets (Latin America) - Opportunities in Brazil, Mexico and Argentina 8
Straight curette with hollow handle and round cup....
Set of 5 large bone curettes. One each of the following: angled small, straight small, angled medium, straight medium, and angled large....
Bone removing chisel for decortication of lumbar vertebral bodies....
Stainless steel bone clamp....
Medicine Products: