Navigation Links
Mayo Clinic researchers building melanoma vaccine to combat skin cancer
Date:3/19/2012

an adapt to the repeated attacks of a healthy immune system and display fewer antigens (or signposts) that the immune system can identify.

Cancers can learn to hide from a normal immune system, but appear unable to escape an immune system trained by the vesicular stomatitis virus with the wide range of DNA used in the library approach.

"Nobody knows how many antigens the immune system can really see on tumor cells," says Dr. Vile. "By expressing all of these proteins in highly immunogenic viruses, we increased their visibility to the immune system. The immune system now thinks it is being invaded by the viruses, which are expressing cancer-related antigens that should be eliminated."

Much immunotherapy research has slowed because of researchers' inability to isolate a sufficiently diverse collection of antigens in tumor cells. Tumors in these scenarios are able to mutate and reestablish themselves in spite of the body's immune system.

The study was a Mayo collaboration with professors Alan Melcher and Peter Selby at the Leeds Institute of Molecular Medicine, University of Leeds, U.K. They were also co-authors.


'/>"/>

Contact: Robert Nellis
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. The West Clinic Joins Cancer Clinics of Excellence (CCE)
2. Stethoscope App gives iPhone New Clinical Skills
3. Mayo Clinic responsible for $22 billion in economic impact, including $9.6 billion in Minnesota
4. Sunquest Introduces Integrated Clinical Environment Physician Portal Solution in US
5. Almac Launches New STEMS System to Transform Temperature Controlled Shipment Monitoring in Clinical Trials
6. Clinical trial underway: Miniature ultrasound device could revolutionize pain relief
7. Sunquest Completes System-Wide Implementation at Cleveland Clinic Hospital Laboratories
8. Michael J. Fox Foundation Awards $1.1 Million For Clinical Trial of Transdermal Nicotine as Disease-Modifying Treatment For Parkinsons
9. NOVAVAX Presents Positive Clinical Results at The World Health Organization Conference, Geneva, Switzerland
10. UCLA Health System Presents: How to Successfully Implement a Clinical Portal
11. International Merchant Advisors CEO Mel Roseman to Discuss New Medical Marijuana Clinics Live on CBS Radio Networks Big Biz Show February 22, 2010 at 1:40 pm PST
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... 2014U.S. military personnel who served in Iraq and ... brain injury (TBI) were compared to military personnel ... reasons. Differences in measures of overall disability, cognitive ... injury are reported in an article in ... Mary Ann Liebert, Inc., publishers. The article is ...
(Date:4/17/2014)... YORK, NY (April 16, 2014) The cause of ... a new study proposes that neurons may be mistaken ... immune system, similar to the way autoimmune diseases like ... the body,s cells. The study was published April 16, ... a new, and likely controversial, idea in Parkinson,s disease; ...
(Date:4/17/2014)... (BUSM) have discovered that the anti-seizure drug ezogabine, ... findings, reported in the American Journal of ... more effective treatments for alcoholism. , Excessive consumption ... of illness and death in the U.S. and ... productivity of workers and necessitating huge health care ...
(Date:4/17/2014)... Spending time online has the potential to ward off ... according to research published online in The ... Sciences . In the article " Internet Use ... States: A Longitudinal Analysis ," the authors report that ... by 33 percent among their study sample. , ...
(Date:4/17/2014)... ribbon representing a disease. A pink ribbon is well known ... think of with lung cancer?, Although white has been identified ... black may be the only one they think fits., A ... smokers between the ages of 51 to 79 years old, ... these patients, the emotional toll it can have and how ...
Breaking Medicine News(10 mins):Health News:Long-term effects of battle-related 'blast plus impact' concussive TBI in US military 2Health News:Is Parkinson's an autoimmune disease? 2Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2Health News:Internet use may cut retirees' depression 2Health News:Unraveling the 'black ribbon' around lung cancer 2
... media and others interested in the chemical sciences are ... American Chemical Society (ACS) Webinars, focusing on how to ... programs. Scheduled for Thursday, Sept. 16, from 2 ... feature Josephine Yuen, Ph.D., NSF Program Director, speaking on ...
... for Personalized Medicine , Author: Shara Yurkiewicz, Summary: Ten ... the human genome, major changes have made their way ... Title: Personalized Medicine,s Ragged Edge, Author: Leonard M. Fleck, ... spin. But little attention has been given to some ...
... , THURSDAY, Sept. 9 (HealthDay News) -- A ... heads-up about the kinds of medical problems that may face ... to use a computational method to create a score based ... rate during the first three hours after birth. In a ...
... living in California, Laotian/Hmong-Americans have the lowest survival rates ... new study by researchers with the UC Davis School ... largest population-based examination of liver cancer rates among Asian-Americans, ... to detect and treat the disease earlier among Laotian/Hmong-Americans, ...
... Academy of Orthopaedic Surgeons (AAOS) recently approved and released ... periprosthetic joint infections of the hip and knee. Clinical ... ensure that patients receive high quality care. A ... organisms enter the wound during or at any point ...
... By Steven Reinberg HealthDay Reporter , ... their ability to lower cholesterol and prevent heart attacks ... rheumatoid arthritis, Israeli researchers report. "We ... were less likely to develop rheumatoid arthritis over a ...
Cached Medicine News:Health News:American Chemical Society Webinar focuses on NSF's small business funding programs 2Health News:The Hastings Center Report table of contents for September-October 2010 2Health News:The Hastings Center Report table of contents for September-October 2010 3Health News:New Tool Aims to Predict Problems in Preemies 2Health News:UC Davis study finds low liver cancer survival rates among Laotian/Hmong-Americans 2Health News:UC Davis study finds low liver cancer survival rates among Laotian/Hmong-Americans 3Health News:Joint replacement: Does this look infected to you? 2Health News:Joint replacement: Does this look infected to you? 3Health News:Statins May Guard Against Rheumatoid Arthritis 2Health News:Statins May Guard Against Rheumatoid Arthritis 3
(Date:1/15/2014)... , Jan. 15, 2014  A novel wearable injector slightly larger ... painless for patients to self-inject prescription drugs in the large ... cancer, blood diseases, autoimmune deficiencies, and genetic disorders.  ... to $220B by 2018, according to analysts.   Many of these ...
(Date:1/14/2014)... 14, 2014  Luminex Corporation (Nasdaq: LMNX ) today ... quarter of 2013 on Monday, February 3, 2014. A press ... close of trading. (Logo: http://photos.prnewswire.com/prnh/20100104/LUMINEXLOGO ) ... the operating highlights and financial results for the fourth quarter ...
(Date:1/14/2014)... Brandeis Medical Center, led by Dr. Emmanuel Brandeis , offers ... tattoo removal experience with the advanced Astanza Duality laser and a ... cosmetic services with cutting edge medical technology and offering expert medical ... has seen a dramatic increase in the presence of tattoo ...
Breaking Medicine Technology:Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... May 26 /PRNewswire-FirstCall/ -- Transgenomic, Inc. (OTC Bulletin Board: TBIO) ... make a presentation regarding the business strategy of the Company at the Noble ... 1:00 p.m. EDT .  The conference will be held at the Hard Rock ... , , ...
... Inteplast Group,s Integrated Bagging Systems (IBS) Unit is ... packaging division from Uniflex Holdings, part of S. Walter Packaging ... and other medical packaging, and is a valued addition to ... name, sales and customer base into the Inteplast fold. , ...
Cached Medicine Technology:Transgenomic to Present at the Noble Financial Sixth Annual Equity Conference - ONTRACK 2010 2Inteplast Acquires Medical Packaging Division 2
... Handbook on Injectable Drugs is a ... it quick and easy to check ... you enter the selected drugs, clear ... so you can quickly take clinical ...
Providing patients and their advocates with a variety of information services and educational materials on clinical research....
... DrDrugs®: Drug Guide for ... over 760 Integrated Calculators ... comprehensive, up-to-date and practical ... in drug dosing calculation ...
Clinician's Pocket Drug Reference 2005 includes key elements of commonly used medications that are essential information for both the student and practicing physician....
Medicine Products: