Navigation Links
Mayo Clinic reports new findings on noninvasive test for pancreatic cancer
Date:5/11/2011

ROCHESTER, Minn. - Pancreatic cancer has one of the highest mortality rates of any of the major cancers, and of the 43,000-plus Americans diagnosed with the disease each year, more than 94 percent die within five years of diagnosis. One reason for this high number of deaths is a lack of effective screening tools for catching the disease early. Now, in an effort to try to gain the upper hand on this deadly form of cancer, Mayo Clinic researchers believe they have found a new way to test for pancreatic cancer with DNA testing of patients' stool samples. The research was presented at the 2011 Digestive Disease Week conference, held May 7󈝶 in Chicago.

"We know with colon cancer that we can detect some molecular signatures of cancers and pre-cancers, and we were interested in trying to determine if we could do the same thing, specifically with a stool test, for pancreas cancer," says John Kisiel, M.D., Mayo Clinic gastroenterologist, who presented the study's findings.

The study focused on detecting methylations in stool samples of 127 patients, 60 diagnosed with pancreatic cancer and 67 who were not diagnosed with cancer. Methylation is a type of DNA modification strongly associated with cancers and pre-cancers. The research team wanted to test if they could reliably detect any types of methylated genes in the stool samples of those in the study group who had already been diagnosed with pancreatic cancer.

"We found that a marker was reliably detected in both tissue samples and in the stools of pancreatic cancer patients, and that it compared favorably with another kind of marker - the mutation of a gene called KRAS," says Dr. Kisiel. "When we looked at those two markers together, the combined accuracy of both markers was significantly better than with either marker alone." Overall, the methylated marker (called BMP3) and the mutated KRAS genes were detected in 70 percent of those in the study who had pancreatic cancer.

Th
'/>"/>

Contact: Brian Kilen
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Watching how cancer patients interact online could help clinicians provide better services
2. Mayo Clinic researchers find new treatment for constipation
3. Mayo Clinic studies how much practice makes perfect when performing colonoscopies
4. Cedars-Sinais mobile medical clinics receive $500,000 grant from California Community Foundation
5. TGen licenses first drug for patient use in clinical care
6. Mayo Clinic CPR efforts successful on man with no pulse for 96 minutes
7. ENERCA clinical recommendations for sickle cell disease management and prevention in children
8. Mayo Clinic finds new genetic cause of neurodegeneration
9. Mayo Clinic finds robotic surgery effective for removing hard-to-reach throat cancer
10. UofL nursing faculty honored for race track clinic success
11. Tierney named 2011 Clinical and Translational Research Distinguished Investigator
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... July 30, 2014 Park Cities ... instituted company-wide staff meetings this month to reinforce best ... Ms. White chose to institute the meetings when ... and amongst staff has become over the past decade. ... her business that allow for quicker processing of customer ...
(Date:7/30/2014)... Ann Arbor, MI, July 31, 2014 Regardless of ... were more likely to develop a drinking problem if ... problems, divorce, and serious financial and legal problems ... by researchers at Columbia University,s Mailman School of Public ... of Preventive Medicine . , Alcohol abuse is a ...
(Date:7/30/2014)... Colorado (PRWEB) July 30, 2014 Daily Gossip ... attacks can occur easily. A panic attack is a feeling ... various factors. There are a series of symptoms that sufferers ... This includes shortness of breath, stress or anxiety. Naturally, panic ... fast and effective way to overcome them. , The 60 ...
(Date:7/30/2014)... The Restore My Blood Sugar review recently published ... levels can now find an amazingly successful method of reducing ... created by D. Chao and Andrew Forester who claim that ... it comes to normalizing blood sugar levels. Chao actually is ... to the cure of diabetes that all patients should find ...
(Date:7/30/2014)... July 30, 2014 Within weeks freshman will begin ... promise. Each hopes this will be a time of growth and ... each to pause; it may not be as easy as it ... students will switch their major at least once and many will ... energy and the costs are exacerbated when switching in the later ...
Breaking Medicine News(10 mins):Health News:Dallas-Based Park Cities Pet Sitter Stresses the Importance of Mindful Communication in This Month’s Staff Meetings, In Addition to Teaching the Signs of Burnout 2Health News:Dallas-Based Park Cities Pet Sitter Stresses the Importance of Mindful Communication in This Month’s Staff Meetings, In Addition to Teaching the Signs of Burnout 3Health News:Dallas-Based Park Cities Pet Sitter Stresses the Importance of Mindful Communication in This Month’s Staff Meetings, In Addition to Teaching the Signs of Burnout 4Health News:Veterans' alcohol problems linked to stress on the home front 2Health News:60 Second Panic Solution Review Reveals Unique Way to Stop Panic Attacks 2Health News:Restore My Blood Sugar Review Reveals Exclusive Ways to Normalize Blood Sugar 2Health News:Advice to College Freshman from Author Garrett Miller 2Health News:Advice to College Freshman from Author Garrett Miller 3
... ... to Los Angeles helped stabilize a flight attendant who suffered a severe injury due to turbulence. ... , ... Dr. Semira Bayati was onboard United Airlines flight 935 when it took off from Heathrow ...
... 1989 a 29-year-old Michael Schrader had it all: steady job, ... He couldn,t envision wanting morethat is, more children. Taking steps ... procedure so routine he was back on the golf course ... but in the years that followed Schrader would ultimately revisit ...
... ... and Health Management Capabilities , ... Farmington, Conn. (Vocus) May 27, 2010 -- Since first announcing its strategic ... company serving employers, plan sponsors and health plans, has dedicated itself to realizing its ...
... about UV light exposure persist, survey finds , THURSDAY, ... by the American Academy of Dermatology finds that many ... themselves from developing skin cancer. , "Our survey showed ... UV exposure and the importance of proper sun protection, ...
... , ... one hundred pediatricians, researchers, policy experts, and other stakeholders from around the Washington, DC, ... the importance of community-wide involvement in any program designed to combat childhood obesity. ... Washington, DC ...
... 17 million children, experience household food insecurity the ... of family members according to the U.S. Department ... when examining the specific food needs of children. In ... food insecurity and hunger among children still persist, even ...
Cached Medicine News:Health News:Orange County Plastic Surgeon Helps Stabilize Wounded Flight Attendant Requiring an Emergency Landing 2Health News:Orange County Plastic Surgeon Helps Stabilize Wounded Flight Attendant Requiring an Emergency Landing 3Health News:Robotic-assisted vasectomy reversal offers greater chance of fatherhood 2Health News:Does Your Health and Wellness Initiative Have Life? 2Health News:Does Your Health and Wellness Initiative Have Life? 3Health News:Many People Still Don't Know How to Protect Against Skin Cancer 2Health News:Childhood Obesity Institute Symposium at Children's National Medical Center Zeroes in on the Importance of Multi-Disciplinary Approach to Curb Childhood Obesity 2Health News:Childhood Obesity Institute Symposium at Children's National Medical Center Zeroes in on the Importance of Multi-Disciplinary Approach to Curb Childhood Obesity 3Health News:Childhood Obesity Institute Symposium at Children's National Medical Center Zeroes in on the Importance of Multi-Disciplinary Approach to Curb Childhood Obesity 4Health News:Childhood Obesity Institute Symposium at Children's National Medical Center Zeroes in on the Importance of Multi-Disciplinary Approach to Curb Childhood Obesity 5Health News:Despite food-assistance programs, many children experience food insecurity, hunger 2
(Date:7/30/2014)... July 30, 2014  InnoPharma, Inc. today announced the ... generic equivalent of Zyprexa® injection), in Canada.  Olanzapine is ... behaviors in patients with schizophrenia or bipolar I mania. ... drug, InnoPharma has entered into an agreement with Sandoz ... will make, use, sell, market and distribute Olanzapine Injection ...
(Date:7/30/2014)... and PARIS , July 30, ... ) and Sanofi (EURONEXT: SAN and NYSE: ... ODYSSEY trials of alirocumab in people with hypercholesterolemia met ... from baseline in low-density lipoprotein cholesterol (LDL-C) at 24 ... an investigational monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin ...
(Date:7/30/2014)... NEW YORK , July 30, 2014 ... products for oncology supportive care, announced that its novel ... featured in an article on OncLive.com titled, "Study Finds ... Neck Cancers."  Dr. Steve Sonis , a leading ... demand seen in the oncology community for evidence-based strategies ...
Breaking Medicine Technology:InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada 2Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 2Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 3Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 4Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 5Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 6Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 7Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 8Access Pharmaceuticals Featured On OncLive.com 2Access Pharmaceuticals Featured On OncLive.com 3
... /PRNewswire-Asia-FirstCall/ -- Golden Meditech Holdings ("Golden Meditech," 0801.HK, ... Bon International") today announced that the companies have ... strategic cooperation in Taipei.  Golden Meditech Holdings Chairman, ... International, Mr. Chu Powei, respectively represented and co-chaired ...
... BRUNSWICK, N.J., and LEIDEN, Netherlands, Feb. 17, 2011 ... (NYSE Euronext, Nasdaq: CRXL ; Swiss Exchange: CRX) today ... to acquire Crucell N.V. (Crucell) has been satisfied.  The initial offering ... a.m. New York time) on 16 February 2011.   ...
Cached Medicine Technology:Golden Meditech to Form Strategic Alliance with Long Bon International 2Golden Meditech to Form Strategic Alliance with Long Bon International 3Minimum Acceptance Condition Satisfied 2Minimum Acceptance Condition Satisfied 3Minimum Acceptance Condition Satisfied 4Minimum Acceptance Condition Satisfied 5Minimum Acceptance Condition Satisfied 6
... Merit Medical is pleased to offer ... The pre-coated, high-performance, InQwire guide wire ... is very lubricious and can help ... available in a wide range of ...
... The MULTI-LINK VISION Coronary Stent System ... of cobalt chromium stents. Cobalt chromium is ... so a cobalt chromium stent can have ... stainless steel stent with struts that are ...
BiodivYsio stent with biocompatible coating (phosphorylcholine)...
... The CYPHER Sirolimus-eluting Coronary ... antiproliferative drug, called "sirolimus", a ... stent delivery platform. Upon placement, ... wall and impedes the process ...
Medicine Products: