Navigation Links
Mayo Clinic-led study identifies biomarkers for early risk assessment of acute kidney injury
Date:2/6/2013

ROCHESTER, Minn. Acute kidney injury strikes large numbers of hospitalized patients, including those with no prior kidney-related illness, and is one of the most costly and deadly conditions affecting critically ill patients. Findings published today in Critical Care from a Mayo Clinic-led, multicenter study identify two biomarkers of acute kidney injury that can be easily measured in urine and detect affected patients roughly 12 to 36 hours earlier than current tests.

"Failure to recognize and manage acute kidney injury in the early stages can lead to devastating outcomes for patients and increased costs to the health care system. Unfortunately, current blood and urine tests are not able to detect it early enough to avoid further complications or provide any chance for intervention," says lead author Kianoush B. Kashani, M.D., a nephrologist and intensivist at Mayo Clinic.

The study's findings give physicians a tool to determine early on whether a patient is at risk, Dr. Kashani says.

Researchers evaluated nearly 340 biomarkers to find the two with the highest correlation to kidney injury risk. The markers, Insulin Growth Factor Binding Protein-7 (IGFBP-7) and Tissue Inhibitor of Metalloproteinases-2 (TIMP-2), were later validated by another multicenter study known as the Sapphire Trial.


'/>"/>

Contact: Rebecca Eisenman
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. Ability to metabolize tamoxifen affects breast cancer outcomes, Mayo Clinic-led study confirms
2. Mayo Clinic-led study unravels biological pathway that controls the leakiness of blood vessels
3. Study to test whether hearing aids can help prevent falls
4. Study identifies skiers who can be successfully treated without surgery after an ACL tear
5. Study of brain cooling and clot-busting drug therapy for stroke receives FDA OK to expand
6. Shift to Hospice Care Often Comes Too Late, Study Finds
7. Steroid Shots for Tennis Elbow Miss the Mark: Study
8. Diabetes Drug May Offer Modest Weight Loss for Very Obese Teens: Study
9. Mammogram every 2 years has same benefit as yearly mammogram for older women, UCSF study finds
10. Sunshine Linked to Lower Rheumatoid Arthritis Risk: Study
11. Patient Involvement Lowers Health Costs, Study Says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... York, NY (PRWEB) , ... May 27, 2016 , ... ... needing intervention to walk, the demand for a sustainable product to aid in the ... void and aid in the recovery of individuals with hemiplegia due to stroke. , ...
(Date:5/27/2016)... ... May 27, 2016 , ... Beleza Medspa has initiated a ... This is the first time that Coolsculpting is being used for for more ... months to ensure they meet the prescribed body-fat standard, measured by the circumference-based tape ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... trusted name in the pharmaceutical, medical and food industries. Aside from its GMP ... certification (SIC), providing proof of successfully certified products, services and staff. , Validation ...
(Date:5/26/2016)... Oakland, California (PRWEB) , ... May 26, 2016 ... ... liabilities associated with discovery of thousands of defective respirators, according to court documents ... in the case of William and Becky Tyler v. American Optical Corporation, Case ...
(Date:5/26/2016)... ... ... On Memorial Day, Hope For Heroes and USA Medical Card will ... country. The nonprofit Hope For Heroes partnered with the leading provider of free ... military veterans, as well as police, firemen, and EMS professionals across the country, and ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... PUNE, India , May 25, 2016 ... "Medical Animation Market by Type (3D, 2D, 4D), by ... Patient Education), by End User (Medical Device Manufacturers, Hospitals/ ... report studies the global Medical Animation Market for the ... expected to reach USD 301.3 Million by 2021 from ...
(Date:5/25/2016)... , May 25, 2016  Zymo Research ... for their new reference materials that help researchers ... sample collection to analyses. The rapid growth of ... for researchers to have standard methods to improve ... generated. Biases inherently exist at every step of ...
(Date:5/25/2016)... SPRINGS, Florida , May 25, 2016 ... Business Conference & Expo earlier this month, the numbers ... As revenues continue to climb into the billions, more ... the newly released 4th Edition State of Legal Marijuana ... Frontier, a cannabis-focused data-analysis firm, much of the increase ...
Breaking Medicine Technology: