Navigation Links
Mayo Clinic Researchers Say Triple Drug Combination is Promising Option to Treat Metastatic HER2+ Breast Cancer
Date:5/18/2009

ORLANDO, Fla., May 18 /PRNewswire-USNewswire/ -- Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options.

At the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO), researchers from the Mayo Clinic campus in Florida report that using a combination of capecitabine, vinorelbine, and trastuzumab offers a treatment option that is at least as beneficial as other current options - and doesn't cause hair loss in patients.

"This is a very well tolerated regimen. The combination is a good example of an excellent therapeutic ratio: good activity and low toxicity," says the study's senior investigator, Edith Perez, M.D., director of Mayo Clinic's Breast Center in Jacksonville.

The clinical trial is the first in the United States to study this particular combination of therapies in patients with HER2+ metastatic breast cancer, researchers say. The chemotherapy regimen was previously tested in Europe and demonstrated good anti-tumor activity and low toxicity, so Mayo researchers combined it with Herceptin, says the study's lead author, Winston Tan, M.D., a medical oncologist at Mayo Clinic.

Sixty-seven percent of the 45 patients in this trial responded to treatment, with their tumors decreasing in size by at least 30 percent. Historic response to conventional drug regimens (one chemotherapy drug with Herceptin) that are currently used to treat metastatic HER2+ breast cancer is about 50 percent, Dr. Tan noted.

"The results are encouraging, and would su
'/>"/>

SOURCE Mayo Clinic
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Two Targeted Therapies Likely Better Than One in Patients with Aggressive Lymphoma, Mayo Clinic Researchers Say
2. Mayo Clinic Researchers Say Agent Provides Treatment Option for Women with Hot Flashes
3. Drug That Targets Vasculature Growth Attacks Aggressive Thyroid Cancer, Mayo Clinic Researchers Report
4. Fate Therapeutics Adds Pratik Multani, M.D., M.S., as Vice President Clinical Development to Advance Upcoming Clinical Programs of Stem Cell Modulators
5. InDex Pharmaceuticals AB Engages PharmaVentures to Facilitate the Licensing of Kappaproct(R) After Phase IIa Trial Achieves Clinical Endpoints Early
6. Frost & Sullivan: Clinical and Cost Benefits to Promote Uptake of Advanced Wound Management Technologies Across Europe
7. Large clinical trial finds pirfenidone may help lung function in IPF patients
8. Fewer Than One Percent of Infertile Couples Who Need Treatment Receive It - Website to Bridge Gap Between Infertile Couples and Fertility Clinics
9. Cleveland Clinic CIO Named to Federal Advisory Committee on Health Information Technology
10. BioVex To Announce Updated Survival Data From a Phase II Clinical Study of OncoVEX GM-CSF in Metastatic Melanoma at The 2009 American Society of Clinical Oncology Meeting
11. Cigna Medical Group Announces Grand Opening of CareToday Clinic in Anthem, Ariz.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... August 20, 2014 Top10BestSEOHosting.com has ... JustHost are the recommended suppliers for the webmasters ... hosting products. , According to the senior spokesman ... the most affordable hosting products on the market ... offer a variety of online deals when service ...
(Date:8/19/2014)... August 19, 2014 “ Inbox Blueprint ... course designed to provide users with the tools necessary ... marketing techniques and strategies. The course which was ... of excitement throughout the internet marketing world. The commotion ... HonestyFirstReviews.com's Tiffany Hendricks prompting an updated review of the ...
(Date:8/19/2014)... August 19, 2014 Horizon Blue Cross Blue ... Morgan Hoffmann are once again teaming up during The ... cause through a Walking Challenge, and Horizon BCBSNJ will be ... a course challenge of their own. , Horizon BCBSNJ, the ... is making a $5,000 donation to the New Jersey Golf ...
(Date:8/19/2014)... (HealthDay News) -- Lupus and other rheumatic diseases ... seizures, which can delay a correct diagnosis for ... rheumatic diseases can also cause these types of ... Center in Maywood, Ill. Rheumatic disorders include ... soft tissues, such as lupus, systemic vasculitis and ...
(Date:8/19/2014)... 2014 Grande Naturals, LLC is ... of the 2014 Independent Cosmetics Manufacturers & Distributors ... place position in “Product Innovation; Product Color Cosmetic” ... also includes a lash enhancement serum, GrandeLINER™. ... technology. , This all-new eyeliner is ...
Breaking Medicine News(10 mins):Health News:Fatcow Awarded As One of the Best Web Hosting Suppliers at Top10bestseohosting.com 2Health News:Anik Singal’s “Inbox Blueprint” Review Released By HonestyFirstReviews.com 2Health News:Horizon Blue Cross Blue Shield of New Jersey Pairs up with PGA TOUR Pro Morgan Hoffmann for Walking Challenge During The Barclays for Charity and to Promote Good Health 2Health News:Horizon Blue Cross Blue Shield of New Jersey Pairs up with PGA TOUR Pro Morgan Hoffmann for Walking Challenge During The Barclays for Charity and to Promote Good Health 3Health News:Horizon Blue Cross Blue Shield of New Jersey Pairs up with PGA TOUR Pro Morgan Hoffmann for Walking Challenge During The Barclays for Charity and to Promote Good Health 4Health News:Certain Symptoms Can Delay Lupus Diagnosis, Researchers Report 2Health News:GrandeLINER™ Wins Independent Cosmetics Manufacturers & Distributors Award 2Health News:GrandeLINER™ Wins Independent Cosmetics Manufacturers & Distributors Award 3
... today that it has dosed its first patient in ... ALT-2074, its lead glutathione peroxidase mimetic, in diabetic ... at high risk for cardiovascular complications. , ... ability to lower inflammatory cardiovascular biomarkers in patients with ...
... (JCVI) today announced the results of work on genome ... bacteria into another type dictated by the transplanted chromosome. ... journal Science, by JCVI's Carole Lartigue, Ph.D. and colleagues, ... bacterial species, Mycoplasma capricolum into another, Mycoplasma mycoides Large ...
... Businesses that offer customers shisha water pipes to smoke tobacco ... smoking ban that comes into force in England on Sunday. ... the water pipes are variously called, dozens of restaurants will ... see their sole activity disappear. ,"It's a disaster, ...
... name, one might rhetorically ask. But Malaccan state authorities have ... after their region. And now the virus will carry some ... announced last week they discovered a new virus likely carried ... called it the Melaka Virus, using the name of the ...
... with most other developing countries, plastic bags have become a terrible ... to be spiraling out of control, the government has announced a ... Uganda they are called buveera , and they are everywhere. ... organized dump like the one at Chitezi in Ugandan capital Kampala. ...
... found that nonsmoking restaurant and bar employees absorb a ... in places where they had to breathe tobacco smoke ... in the body only as a result of using ... the Multnomah County Health Department and Oregon Department of ...
Cached Medicine News:Health News:Alteon Initiates Phase 2 Trial of ALT-2074 in Diabetes and Haptoglobin 2-2 2Health News:First Bacterial Genome Transplantation Changing One Species to Another 2Health News:Shisha Owners Mobilise Against July 1 Smoking Ban in England 2Health News:Shisha Owners Mobilise Against July 1 Smoking Ban in England 3Health News:Mealaka Virus Will Have a New Name 2Health News:Uganda Bans Plastic Bags, Still a Tough Battle Lies Ahead 2Health News:Non Smoking Workers Absorb the Carcinogen Immediately 2Health News:Non Smoking Workers Absorb the Carcinogen Immediately 3
(Date:8/19/2014)... Research and Markets has announced the addition of the ... to their offering. This report analyzes the ... following three major Application Areas: General/Abdominal Surgery, Pelvic/Gynecological Surgery, and ... analytics for the US, Canada , ... Asia-Pacific , Latin America , ...
(Date:8/19/2014)... 19, 2014 ,Weight Loss- Market ... 2014, report provides comprehensive insights about phase III pipeline ... objective of the report is to establish the understanding ... drugs across the different countries and regions. While the ... report also provides details on the drug master filings ...
(Date:8/18/2014)... Elbit Imaging Ltd. ("EI" or ... today that Elbit Medical Technologies Ltd. ("Elbit Medical") (TASE: ... holds approximately 86% of the voting power, announced that ... Elbit Medical holds approximately 30.8% of the voting power ... shareholders (including Elbit Medical), signed Option and Investment Agreements ...
Breaking Medicine Technology:Global Anti-Adhesion Products - Strategic Business Report 2014 2Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 2Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 3Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 4Elbit Imaging Announces Gamida Cell Signs Option and Investment Agreements with Major Pharmaceutical Company 2Elbit Imaging Announces Gamida Cell Signs Option and Investment Agreements with Major Pharmaceutical Company 3
... to the FDA, LAUSANNE, Switzerland, November ... development specialist that,focuses on serious medical conditions ... its Canadian affiliate, filed its Complete,Response to ... States (U.S.),Food and Drug Administration (FDA) for ...
... ANTIPOLIS, France, November 4 NicOx,S.A. (Euronext Paris: ... patient Ambulatory Blood Pressure Monitoring (ABPM) trial (the ... of escalating,doses of naproxcinod and naproxen in osteoarthritis ... was the mean 24-hour,ambulatory systolic blood pressure (SBP) ...
Cached Medicine Technology:Sanvar(R) (Debio 8609) for Esophageal Variceal Bleeding 2Sanvar(R) (Debio 8609) for Esophageal Variceal Bleeding 3NicOx Announces Favorable Blood Pressure Data for Naproxcinod in a Large ABPM Study 2NicOx Announces Favorable Blood Pressure Data for Naproxcinod in a Large ABPM Study 3NicOx Announces Favorable Blood Pressure Data for Naproxcinod in a Large ABPM Study 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: