Navigation Links
Mayo Clinic Researchers Say Triple Drug Combination is Promising Option to Treat Metastatic HER2+ Breast Cancer
Date:5/18/2009

ORLANDO, Fla., May 18 /PRNewswire-USNewswire/ -- Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options.

At the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO), researchers from the Mayo Clinic campus in Florida report that using a combination of capecitabine, vinorelbine, and trastuzumab offers a treatment option that is at least as beneficial as other current options - and doesn't cause hair loss in patients.

"This is a very well tolerated regimen. The combination is a good example of an excellent therapeutic ratio: good activity and low toxicity," says the study's senior investigator, Edith Perez, M.D., director of Mayo Clinic's Breast Center in Jacksonville.

The clinical trial is the first in the United States to study this particular combination of therapies in patients with HER2+ metastatic breast cancer, researchers say. The chemotherapy regimen was previously tested in Europe and demonstrated good anti-tumor activity and low toxicity, so Mayo researchers combined it with Herceptin, says the study's lead author, Winston Tan, M.D., a medical oncologist at Mayo Clinic.

Sixty-seven percent of the 45 patients in this trial responded to treatment, with their tumors decreasing in size by at least 30 percent. Historic response to conventional drug regimens (one chemotherapy drug with Herceptin) that are currently used to treat metastatic HER2+ breast cancer is about 50 percent, Dr. Tan noted.

"The results are encouraging, and would su
'/>"/>

SOURCE Mayo Clinic
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine news :

1. Two Targeted Therapies Likely Better Than One in Patients with Aggressive Lymphoma, Mayo Clinic Researchers Say
2. Mayo Clinic Researchers Say Agent Provides Treatment Option for Women with Hot Flashes
3. Drug That Targets Vasculature Growth Attacks Aggressive Thyroid Cancer, Mayo Clinic Researchers Report
4. Fate Therapeutics Adds Pratik Multani, M.D., M.S., as Vice President Clinical Development to Advance Upcoming Clinical Programs of Stem Cell Modulators
5. InDex Pharmaceuticals AB Engages PharmaVentures to Facilitate the Licensing of Kappaproct(R) After Phase IIa Trial Achieves Clinical Endpoints Early
6. Frost & Sullivan: Clinical and Cost Benefits to Promote Uptake of Advanced Wound Management Technologies Across Europe
7. Large clinical trial finds pirfenidone may help lung function in IPF patients
8. Fewer Than One Percent of Infertile Couples Who Need Treatment Receive It - Website to Bridge Gap Between Infertile Couples and Fertility Clinics
9. Cleveland Clinic CIO Named to Federal Advisory Committee on Health Information Technology
10. BioVex To Announce Updated Survival Data From a Phase II Clinical Study of OncoVEX GM-CSF in Metastatic Melanoma at The 2009 American Society of Clinical Oncology Meeting
11. Cigna Medical Group Announces Grand Opening of CareToday Clinic in Anthem, Ariz.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... According to an article in the June ... nearly 30 million Americans tan indoors each year and an ... knowing the health risks. New research suggests that UV ... on the brains of some tanners (Go to goo.gl/hdwnz). ... I can’t say that I fully support this contention from ...
(Date:5/25/2013)... Dr. Leslie Gerstman announced today ... lift skin on the neck, on the brow and under ... Aesthetics. , Ultherapy is a non-surgical procedure for the face ... to lift the skin over time. The use of FDA-cleared ... and then treat the deepest support layers of the skin ...
(Date:5/25/2013)... 2013 A disorder of the nerves, ... neuropathy. According to neuropathy expert doctor Helen C Lin, ... that the disorder affects almost 50% of all Diabetic ... Diabetes. The high blood sugar levels in the body ... from it usually tend to have abnormally high blood ...
(Date:5/25/2013)... The report “Global Food Encapsulation Market (2012 – ... Materials, Packaging, & Geography: Trends & Forecasts” defines ... analysis and forecasting of the global revenue for ... restraining factors for the global food encapsulation markets ... market is segmented and revenue are forecasted on ...
(Date:5/25/2013)... 25, 2013 Absolute Surgical Specialists, serving Sun ... the NALA’s businesses throughout the country participating in Shop Local ... in the nationwide event as he understands what military families ... the Army. He said, “I wanted to give something back, ... but I live here too.” , Shop Local for a ...
Breaking Medicine News(10 mins):Health News:Sun Damage – Are UV Rays Addictive? 2Health News:Dr. Leslie Gerstman Is Now Offering the Non-surgical Facelifting Procedure – Ultherapy – in NYC and NJ 2Health News:Diabetic Neuropathy treatment hits new grounds- Neuracel launches the complete natural treatment 2Health News:Food Encapsulation Market to Reach $42 Billion by 2016 - New Report by MarketsandMarkets 2Health News:Food Encapsulation Market to Reach $42 Billion by 2016 - New Report by MarketsandMarkets 3Health News:Dr. Craig Amshel of Absolute Surgical Specialists Offering Bowel Prep During the Shop Local for a Cause Event 2
... ... HIV STOPS WITH US",is the message of ... across,the country including: Boston, Long Beach and Alameda ... positive people, and a,wide spectrum of HIV negative ... providers and partners talking about real issues., ...
... using widely available and inexpensive ultrasound imaging could help ... or other adverse cardiovascular events, according to a study ... Radiology . , Researchers performed ultrasound imaging on the ... at high risk for cardiovascular disease. Of those, ultrasound ...
... reduces bleeding problems, study finds , , MONDAY, Aug. 18 (HealthDay ... wrist rather than the groin reduces the incidence of bleeding ... using the radial artery in the wrist, is not widely ... almost 600,000 catheterizations in a national database, said a report ...
... Arizona hospitals can access the new AzHHA pharmacy benefit ... immediately see improvements to their bottom ... created and is,supported by the leading pharmacy benefit consulting ... rebate,reimbursements, implementation credits and many other options not typically,available ...
... 18 Today a representative of the,Executive Board ... Local,6434 ("ULTCW") filed a letter of complaint with ... the letter written to President Stern and the ... Vice President of ULTCW and,member of its Executive ...
... Aug. 18 Actavis Group, the,international generic ... approval from the U.S. Food & Drug ... 300mg. Distribution,of the product will commence immediately., ... in,300mg strength, are the generic equivalent of ...
Cached Medicine News:Health News:New HIV Prevention/Anti-Stigma Campaign Featuring HIV Positive & Negative Persons 'TOGETHER' Launches Across the Nation 2Health News:Ultrasound used to predict heart attack risk 2Health News:Reaching the Heart Through the Wrist 2Health News:Reaching the Heart Through the Wrist 3Health News:Arizona Hospital and Healthcare Association Teams Up with ARMSRx to Bring Cost Savings to Hospitals 2Health News:Actavis Receives Approval of Generic Wellbutrin XL(R) 300mg in the U.S. 2
(Date:5/23/2013)... 3SBio Inc. (NASDAQ: SSRX ... China -based biotechnology company focused on ... today that, at an extraordinary general meeting held ... favor of the proposal to authorize and approve ... dated February 8, 2013, among Decade Sunshine Limited, ...
(Date:5/23/2013)... Corporation (NYSE: HAE ) announced today that ... present at The Deutsche Bank 38 th Annual dbAccess ... on May 29, 2013 at 1:30pm Eastern time.  ... may access Mr. Lindop,s presentation live via webcast at: ... (NYSE: HAE ) is a global healthcare company ...
(Date:5/23/2013)... , May 23, 2013  TeamHealth Medical ... nurse triage and nurse advice lines, announces its ... comprising physician, nursing and administrative leaders, provides clinical ... quality and cost-effective services for hospital clients, physician ... national healthcare system evolves, it,s imperative to continuously ...
Breaking Medicine Technology:3SBio Inc. Announces Shareholders' Approval of the Amended Merger Agreement 23SBio Inc. Announces Shareholders' Approval of the Amended Merger Agreement 3TeamHealth Medical Call Center Forms Clinical Advisory Committee 2
... N.M., Jan. 26, 2011 New Mexico Software, ... a developer of medical IT services and solutions that ... announced today the implementation of a software module that ... XR-EXpress telemedicine services to other systems. CEO ...
... Solta Medical, Inc. (Nasdaq: SLTM ), a ... it will release its financial results for the full year ... on Tuesday, February 22, 2011.  The Company will also host ... at 4:30 p.m. Eastern Time (1:30 p.m. Pacific) to discuss ...
Cached Medicine Technology:New Mexico Software Unveils Additional Software Significantly Expanding Availability of Its Telemedicine Services 2New Mexico Software Unveils Additional Software Significantly Expanding Availability of Its Telemedicine Services 3Solta Medical Announces Full Year and Fourth Quarter 2010 Results Release and Conference Call 2
Titanium hoskin suture tying forceps, 4.75"....
Castroviejo McPherson angled tying forceps with 10 mm tips and 5mm titanium coated platforms. Length 110 mm....
Castroviejo colibri tying forceps with 5 mm tips and 5 mm titanium coated platforms. Length 110 mm....
Tennant angled tying forceps with extra delicate smooth jaws, 6 mm tying platform, For 9-0 to 11-0 sutures. Overall length 108 mm....
Medicine Products: