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Mayo Clinic Research Shows U.S. Intensive Care Units' Prevention of Pneumonia in Critically-ill Patients Generally Strong; Identifies Area of Improvement
Date:5/20/2008

st be on an invasive mechanical ventilator greater than 48 hours," says Mayo lead author Ahmed Mahmoud, M.B.B.S.

"As the demographics of this country change, the number of frail elderly who end up hospitalized and needing ventilation in a TICU is likely to increase," adds senior author Bekele Afessa, M.D., of Mayo's pulmonary and critical care medicine group. "We want to do our best to eliminate the potential for any additional disease burden to patients. Understanding the risk of VAP in all ICU settings is a step toward that."

The Mayo study is the first to compare VAP-risk rates at (NHSN) hospitals to Mayo Clinic's experience as a single advanced medical center with integrated intensive care units and a unified approach to infection control. Mayo Clinic researchers studied 206 patients treated at Mayo Clinic's various ICUs between February and August 2007, and who consented to participate in the study.

Results

The Mayo Clinic comparison also showed that:

*The VAP-risk rate varies depending on the ICU medical specialty, from a low of 2.8 at Mayo Clinic's vascular/thoracic surgery intensive care unit and 5.7 in the analogous units of NHSN to a high of 10.2 per 1,000 ventilator days in NHSN trauma intensive care units.

*The Mayo VAP-risk data range from 2.8 to 8.2 across various kinds of ICUs at Mayo Clinic; 2.8 for vascular and thoracic surgery, 8.2 for neurology and 4.9 for cardiac surgery.

*Of the 19 bacteria isolated from the patients, the Mayo study found that the most common pathogen causing VAP was Pseudomonas aeruginosa. This information is helpful in determining the best antibiotic treatment for VAP. Acting on it could perhaps help prevent levels of VAP elsewhere.

Support

The study was funded by the Mayo Foundation for Medical Education and Research.

To obtain the latest news releases from Mayo Clinic, go to http://www.mayoclinic.org/n
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SOURCE Mayo Clinic Public Affairs
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