Navigation Links
Mayo Clinic Research Shows U.S. Intensive Care Units' Prevention of Pneumonia in Critically-ill Patients Generally Strong; Identifies Area of Improvement

TORONTO, May 20 /PRNewswire-USNewswire/ -- Mayo Clinic researchers found that the frequency with which critically-ill patients developed ventilator-associated pneumonia (VAP) is approximately the same at a multidisciplinary medical center such as Mayo Clinic compared to the average VAP-risk rate for 211 hospitals in the National Healthcare Safety Network (NHSN). This is good news for patients because it suggests that care levels are generally strong across the U.S. in intensive care units, which is where the sickest patients -- many of them elderly -- are treated. This is true despite variety in levels of care offered by individual hospitals.

The study also is helpful because it identified the fact that the VAP-risk rate for patients in a specific kind of intensive care unit, the trauma intensive care unit (TICU), was lower at Mayo Clinic, as compared to the NHSN average. This kind of finding is what the U.S. Centers for Disease Prevention and Control (CDC) intended when it made the NHSN data available in a June 2007 report. In that report, CDC analysts instructed hospitals to use the data to guide local prevention strategies and other quality improvement efforts aimed at reducing infection rates. The Mayo group presented its findings this week at the American Thoracic Society's 2008 International Conference in Toronto. The data showed that the Mayo Clinic risk rate for VAP in intensive care units (ICU) for trauma patients averaged 3.4 per 1,000 days of mechanical ventilation. This compares to the VAP average of 10.2 per 1,000 days in trauma ICUs participating in the NHSN.

The reason for this variation is not known, and the difference needs to be validated through further study. But these preliminary results identify a need for improvement to lower the 10.2 risk rate.

Significance of the Mayo Clinic Research

"The topic is an important one to study because developing VAP is a potential risk for all critically-ill patients who must be on an invasive mechanical ventilator greater than 48 hours," says Mayo lead author Ahmed Mahmoud, M.B.B.S.

"As the demographics of this country change, the number of frail elderly who end up hospitalized and needing ventilation in a TICU is likely to increase," adds senior author Bekele Afessa, M.D., of Mayo's pulmonary and critical care medicine group. "We want to do our best to eliminate the potential for any additional disease burden to patients. Understanding the risk of VAP in all ICU settings is a step toward that."

The Mayo study is the first to compare VAP-risk rates at (NHSN) hospitals to Mayo Clinic's experience as a single advanced medical center with integrated intensive care units and a unified approach to infection control. Mayo Clinic researchers studied 206 patients treated at Mayo Clinic's various ICUs between February and August 2007, and who consented to participate in the study.


The Mayo Clinic comparison also showed that:

*The VAP-risk rate varies depending on the ICU medical specialty, from a low of 2.8 at Mayo Clinic's vascular/thoracic surgery intensive care unit and 5.7 in the analogous units of NHSN to a high of 10.2 per 1,000 ventilator days in NHSN trauma intensive care units.

*The Mayo VAP-risk data range from 2.8 to 8.2 across various kinds of ICUs at Mayo Clinic; 2.8 for vascular and thoracic surgery, 8.2 for neurology and 4.9 for cardiac surgery.

*Of the 19 bacteria isolated from the patients, the Mayo study found that the most common pathogen causing VAP was Pseudomonas aeruginosa. This information is helpful in determining the best antibiotic treatment for VAP. Acting on it could perhaps help prevent levels of VAP elsewhere.


The study was funded by the Mayo Foundation for Medical Education and Research.

To obtain the latest news releases from Mayo Clinic, go to ( is available as a resource for your health stories. For more on Mayo Clinic research, go to www

SOURCE Mayo Clinic Public Affairs
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Anemia and tropical diseases; Is pharmacogenomics ready for the clinic?
2. Radiologists encouraged to look beyond cancer for clinically unseen diseases
3. Clinical depression linked to abnormal emotional brain circuits
4. Preclinical study suggests organ-transplant drug may aid in lupus fight
5. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
6. AASM encourages those student-athletes at risk for developing osa to visit a sleep clinic
7. Thailand: Partners Open Free AIDS Treatment Clinic in Renowned AIDS Temple in Lop Buri
8. MinuteClinic Becomes Participating Provider with Assurant Health
9. Therap Services Continues to Hire Experienced Developmental Disability Industry Clinicians for its Customer Support Team
10. Acupuncturists Relocation Tightens Relationship With Fertility Clinic
11. Cardiovascular Technologies to be Highlighted at 5th Annual Cleveland Clinic Medical Innovation Summit, Oct. 1-3
Post Your Comments:
(Date:11/25/2015)... ... ... For the first time, Vitalalert is donating half of its earnings to ... between the two groups began in 2014 with Vitalalert pledging a portion of every ... founded in 1954 and is an international Christian-based health organization whose mission is to ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... According to ... surgical robot is being more and more widely heralded as a breakthrough for performing ... Vinci method has over traditional laparoscopic surgery is that it can greatly reduce the ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... people across the country to celebrate their sobriety and show through pictures what ... “before and after” photos this Thanksgiving with the hashtag #FacesOfGratitude on their Facebook, ...
(Date:11/25/2015)... ... November 25, 2015 , ... Dental professionals who would like to become more ... to attend Dr. Mark Iacobelli’s Advanced Implant Mentoring (AIM) CE course. Courses will be ... As the co-founders of Advanced Implant Mentoring (AIM), Dr. Iacobelli and Dr. D’Orazio are ...
(Date:11/25/2015)... ... November 25, 2015 , ... On November 25, 2015, officials of ... network, announced the release of a new cutting edge recovery program that has been ... working with drug- and alcohol-addicted individuals with the purpose to free addicts from the ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... N.Y. , Nov. 25, 2015  Linden Care, ... and optimizing treatment outcomes for patients suffering from chronic ... request for a Temporary Restraining Order (TRO) enjoining Express ... the two companies. --> ... pursuing all of its legal options. ...
(Date:11/25/2015)... WILMINGTON, N.C. , Nov. 25, 2015 /PRNewswire/ ... announces the planned investment of at least $15.8 ... in Wilmington, NC . The ... services capacity to meet the growing demands of ... Wilmington site expansion will provide up ...
(Date:11/25/2015)... -- On Tuesday, November 24, 2015, the jury ... Medical Technology, Inc. for product liability and misrepresentation ... device, awarded $11 million in favor of Plaintiff ... three days of deliberations, the jury found that ... and unreasonably dangerous, and that Wright Medical made ...
Breaking Medicine Technology: