Navigation Links
Mayo Clinic Proceedings: Researchers find evidence of survival gains in bone marrow disease
Date:12/14/2009

ROCHESTER, Minn. -- A recent study, published in the December issue of Mayo Clinic Proceedings, demonstrates new survival data for the blood disorder myelofibrosis. This retrospective study is the largest ever conducted in young patients with primary myelofibrosis.

Myelofibrosis is a serious disorder that disrupts the body's normal production of blood cells. The result is extensive scarring in the bone marrow, leading to severe anemia, weakness, fatigue and often, an enlarged spleen and liver.

"In the past 20 years, management of primary myelofibrosis has incorporated new treatment approaches, but survival benefits for patients have not been confirmed," says Ayalew Tefferi, M.D., senior author of the study and a Mayo Clinic hematologist. "Our study reviewed almost 30 years of data on myelofibrosis to obtain mature survival data in the particular patient population."

Study findings suggest that high- to intermediate-risk patients in whom the diagnosis of primary myelofibrosis was made after 1986 lived longer than those whose diagnosis was made earlier. The improvement in survival was most impressive for patients whose diagnosis was made in the most recent decade (ie, 1996-2005) in which median survival was not reached.

"Such retrospective studies cannot accurately identify the reasons for improved survival but alert clinical investigators to avoid using historical controls to determine the value of new treatment modalities such as allogeneic hematopoietic cell transplantation," says Dr. Tefferi.

"These observations are encouraging and suggest a beneficial effect from modern therapeutic approaches in myelofibrosis. The current findings are based on retrospective observation and need to be validated in properly designed prospective studies."


'/>"/>

Contact: Rebecca Finseth
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. Mayo Clinic researchers say breast cancer survival improves Herceptin used with chemotherapy
2. Clinical trial advances new approach to re-sensitizing breast cancer
3. HealthWyse Clinical and Financial Point of Care Software Addresses OASIS-C Regulations and More
4. Drug Information Association (DIA) Announces New Clinical Safety and Pharmacovigilance Certificate Program
5. Macomb County Announces New Location for Four Upcoming H1N1 Clinics
6. Most Antidepressants Miss Key Target of Clinical Depression
7. Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing
8. Quantros(TM) Unveils Clinical Cafe, Social Networking Website for Healthcare Professionals Focused on Safety, Quality and Compliance
9. Pharmacyclics, Inc. Reports Interim Safety and Clinical Data from a Phase I/II Clinical Trial of its Oral HDAC Inhibitor PCI-24781 in Lymphoma at the American Society of Hematology Annual Meeting
10. Free Health Clinic Event Is Not Just for the Sick
11. Childrens Hospitals and Clinics of Minnesota Receives National Recognition for Quality and Efficiency
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... , ... The Radiology Business Management Association will select the 2017 ... Building Better Radiology Marketing Programs conference, held this year from March 5 ... awards are given out in five categories. They are:, ,     Patient ...
(Date:2/23/2017)... ... 23, 2017 , ... On February 22, 2017 the U.S. ... to withdraw previous guidance issued by the Obama Administration requiring schools to treat ... 2016 by the Obama Administration came in response to a growing number of ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... Los Angeles-based ... episodes of WE TV’s “Mama June: From Not to Hot,” which will begin airing ... “Mama” June Shannon, known to millions from the 2012 reality television series, “Here Comes ...
(Date:2/23/2017)... ... February 23, 2017 , ... Dr. David Mahon leads Siena Dental, ... Dr. Mahon was named a 2017 Top Patient Rated Henderson Dentist by ... directory that recognizes local physicians and dentists who have earned high ratings and superior ...
(Date:2/23/2017)... Lincoln, RI (PRWEB) , ... February 23, 2017 ... ... announced today a new partnership with the Rhode Island Consortium for Autism Research ... provide an opportunity for children with autism spectrum disorder (ASD) to see films ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Calif. , Feb. 23, 2017 ... leading the discovery and development of innovative medicines targeting ... full year 2016 financial results on Thursday, March 2, ... host a conference call and webcast on March 2, ... quarter and full year 2016 financial results and provide ...
(Date:2/23/2017)... ... Research and Markets has announced the addition of the "Global ... report to their offering. The Global Antifungal Drugs Market ... next decade to reach approximately $12.8 billion by 2025. ... the given segments on global as well as regional levels presented in ...
(Date:2/23/2017)... Ga., Feb. 23, 2017  MiMedx Group, Inc. (NASDAQ: ... tissue and patent-protected processes to develop and market advanced ... Spine, Sports Medicine, Ophthalmic, and Dental sectors of healthcare, ... and full year ended December 31, 2016. ... Revenue is a 31% increase over full year 2015 ...
Breaking Medicine Technology: