Navigation Links
Mayo Clinic Proceedings: Researchers find evidence of survival gains in bone marrow disease
Date:12/14/2009

ROCHESTER, Minn. -- A recent study, published in the December issue of Mayo Clinic Proceedings, demonstrates new survival data for the blood disorder myelofibrosis. This retrospective study is the largest ever conducted in young patients with primary myelofibrosis.

Myelofibrosis is a serious disorder that disrupts the body's normal production of blood cells. The result is extensive scarring in the bone marrow, leading to severe anemia, weakness, fatigue and often, an enlarged spleen and liver.

"In the past 20 years, management of primary myelofibrosis has incorporated new treatment approaches, but survival benefits for patients have not been confirmed," says Ayalew Tefferi, M.D., senior author of the study and a Mayo Clinic hematologist. "Our study reviewed almost 30 years of data on myelofibrosis to obtain mature survival data in the particular patient population."

Study findings suggest that high- to intermediate-risk patients in whom the diagnosis of primary myelofibrosis was made after 1986 lived longer than those whose diagnosis was made earlier. The improvement in survival was most impressive for patients whose diagnosis was made in the most recent decade (ie, 1996-2005) in which median survival was not reached.

"Such retrospective studies cannot accurately identify the reasons for improved survival but alert clinical investigators to avoid using historical controls to determine the value of new treatment modalities such as allogeneic hematopoietic cell transplantation," says Dr. Tefferi.

"These observations are encouraging and suggest a beneficial effect from modern therapeutic approaches in myelofibrosis. The current findings are based on retrospective observation and need to be validated in properly designed prospective studies."


'/>"/>

Contact: Rebecca Finseth
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. Mayo Clinic researchers say breast cancer survival improves Herceptin used with chemotherapy
2. Clinical trial advances new approach to re-sensitizing breast cancer
3. HealthWyse Clinical and Financial Point of Care Software Addresses OASIS-C Regulations and More
4. Drug Information Association (DIA) Announces New Clinical Safety and Pharmacovigilance Certificate Program
5. Macomb County Announces New Location for Four Upcoming H1N1 Clinics
6. Most Antidepressants Miss Key Target of Clinical Depression
7. Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing
8. Quantros(TM) Unveils Clinical Cafe, Social Networking Website for Healthcare Professionals Focused on Safety, Quality and Compliance
9. Pharmacyclics, Inc. Reports Interim Safety and Clinical Data from a Phase I/II Clinical Trial of its Oral HDAC Inhibitor PCI-24781 in Lymphoma at the American Society of Hematology Annual Meeting
10. Free Health Clinic Event Is Not Just for the Sick
11. Childrens Hospitals and Clinics of Minnesota Receives National Recognition for Quality and Efficiency
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... NJ (PRWEB) September 18, 2014 ... firm, announced today that President and co-founder John ... Journal’s Innovation Award Winners for 2014, recognizing the ... him as an emerging executive of the year. ... care and life sciences that continue to shape ...
(Date:9/18/2014)... Qualis Health, one of the nation’s leading ... paper, “Advancing Primary Care through the Patient-Centered Medical Home ... Authors Jeff Hummel, MD, MPH and Peggy C. Evans, ... in the work of becoming a Patient-Centered Medical Home ... objectives, such as generating and providing useful data that ...
(Date:9/18/2014)... Baltimore, MD (PRWEB) September 18, 2014 ... Award-winning celebrity and wellness advocate, and Frank Davis, ... Activz Whole-food Nutrition, are pleased to announce ... 150+ ways to make delicious, nutrition-packed meals using ... book is the next step in the ...
(Date:9/18/2014)... of international scientists have developed a new method to ... . , The Wildlife Conservation Society (WCS)-led research, published ... , describes the use of fecal samples from wild ... exposed to the virus. This represents a new tool ... change the way Ebola virus is studied and improve ...
(Date:9/18/2014)... expect to pay higher employee contributions for their health ... officers about the impact of the Patient Protection and ... conducted by the Darla Moore School of Business at ... Patrick Wright, a professor in strategic human resource management, ... Officers. The survey is distributed to more than 560 ...
Breaking Medicine News(10 mins):Health News:TayganPoint Executive Receives Prestigious Award from Philadelphia Business Journal 2Health News:Advancing Primary Care Through PCMH and HIT: New White Paper Connects the Dots 2Health News:Montel Williams and Frank Davis Announce New Whole-Food Nutrition Recipe Book, The Simple Scoop, at Natural Products Expo East In Baltimore 2Health News:Montel Williams and Frank Davis Announce New Whole-Food Nutrition Recipe Book, The Simple Scoop, at Natural Products Expo East In Baltimore 3Health News:Research yields a game changer for improving understanding of Ebola and great apes 2Health News:Research yields a game changer for improving understanding of Ebola and great apes 3Health News:Survey: Fortune 500 employees can expect to pay more for health insurance 2Health News:Survey: Fortune 500 employees can expect to pay more for health insurance 3
... regional networks , , FRIDAY, April 24 (HealthDay News) ... laboratory personnel has led to steady improvements in the ... a severe heart attack, new research shows. , The ... ST elevation myocardial infarction (STEMI), the deadliest type of ...
... Though soldiers tend to be healthier, trauma erases the advantage, ... Those serving in the armed forces tend to be in ... experienced combat duty, that initial health advantage is erased. , ... life than do non-combat veterans, according to a study that ...
... N.C. (April 23, 2009) Talecris Biotherapeutics, Inc. ... of life results from the largest clinical trial ... polyneuropathy (CIDP) in the April 14, 2009 issue ... that long-term treatment with Gamunex (Immune Globulin Intravenous ...
... ANGELES , April 24 MMR Information ... its wholly-owned operating subsidiary, MyMedicalRecords, Inc. (collectively, "MMR") ... www.mymedicalrecords.com ) and electronic safe deposit box ... a Webinar on the company,s products for healthcare ...
... ABC,s hit television show Grey,s Anatomy has selected the ... its favorite charities and has listed the AAN Foundation on the Grey,s ... and Dr. Derek "McDreamy" Shepherd. Fans and the public are encouraged ... lieu of gifts. The public can buy a virtual brain for ...
... "Pregnant women need our assistance now so that abortion ... April 24 Cardinal Rigali, chair of the Committee ... Bishops (USCCB), wrote to all U.S. Representatives urging them ... 2035) re-introduced in the House by Rep. Lincoln Davis ...
Cached Medicine News:Health News:Coordination Has Led to Quicker Heart Treatment 2Health News:Combat Duty Harms Long-Term Health of Vets 2Health News:Combat Duty Harms Long-Term Health of Vets 3Health News:Landmark study demonstrates Gamunex improves health-related quality of life in patients with CIDP 2Health News:Landmark study demonstrates Gamunex improves health-related quality of life in patients with CIDP 3Health News:MMR Announces Webinar to Demonstrate MyMedicalRecords PHR Product Line 2Health News:MMR Announces Webinar to Demonstrate MyMedicalRecords PHR Product Line 3Health News:AAN Foundation Benefits from Grey's Anatomy 'Wedding Registry' 2Health News:Cardinal Rigali Praises House Re-Introduction of 'Pregnant Women Support Act,' Urges Co-Sponsorship 2
(Date:9/18/2014)... DALLAS , September 18, 2014 ... "Temperature Management Market by Product (Surface & Intravascular Systems- Warming ... Suite), End User (Surgeon & Anesthesiologist, Nursing & ... 2019" published by MarketsandMarkets, this report studies the global ... 2014 to 2019. The market is expected to ...
(Date:9/18/2014)... , Sept. 18, 2014  Decision Resources Group ... the United States , 54 percent ... BRAF inhibitor Tafinlar for BRAF -mutation-positive unresectable ... have prescribed GlaxoSmithKline,s MEK inhibitor Mekinist. Among current ... (42 percent and 43 percent, respectively) expects to ...
(Date:9/18/2014)... Sept. 18, 2014  KIYATEC announced today that ... Business Innovation Research (SBIR) Phase II Contract from ... 27 institutes and centers that comprise the National ... the two year award, KIYATEC will expand its ... at the forefront of cancer therapy strategies: 1) ...
Breaking Medicine Technology:Temperature Management Market Worth $2.5 Billion by 2019 2Temperature Management Market Worth $2.5 Billion by 2019 3Temperature Management Market Worth $2.5 Billion by 2019 4At One Year Post-Launch, Approximately One Half of Surveyed U.S. Medical Oncologists Have Prescribed Single-Agent Tafinlar and Mekinist to Their Malignant Melanoma Patients 2National Cancer Institute Awards KIYATEC Nearly $2M to Advance Predictive Cancer Diagnostics 2National Cancer Institute Awards KIYATEC Nearly $2M to Advance Predictive Cancer Diagnostics 3
... Mich., Nov. 15, 2010 Adeona Pharmaceuticals, Inc. ... for serious central nervous system diseases, announced today its third ... operational achievements. Adeona,s Recent Clinical and Operational ... Alzheimer,s Disease All 60 patients ...
... to demo a new tool for personalized preventive medicine ... applying for FDA clearance, this comprehensive risk assessment tool, ... the thickness of the C-IMT and detects plaque in ... for screening and unlike anything else out there. ...
Cached Medicine Technology:Adeona Announces Third Quarter 2010 Financial Results and Achievements 2Adeona Announces Third Quarter 2010 Financial Results and Achievements 3Adeona Announces Third Quarter 2010 Financial Results and Achievements 4Adeona Announces Third Quarter 2010 Financial Results and Achievements 5Panasonic Unveils CardioHealth® Station - First Comprehensive Screening Solution to Detect Heart Disease in Asymptomatic Population 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: