Navigation Links
Mayo Clinic: Proton therapy has advantages over IMRT for advanced head and neck cancers
Date:7/1/2014

Rochester, Minn. -- A new study by radiation oncologists at Mayo Clinic comparing the world's literature on outcomes of proton beam therapy in the treatment of a variety of advanced head and neck cancers of the skull base compared to intensity modulated radiation therapy (IMRT) has found that proton beam therapy significantly improved disease free survival and tumor control when compared to IMRT. The results appear in the journal Lancet Oncology.

"We undertook a systematic review and meta-analysis to compare the clinical outcomes of patients treated with proton therapy with patients receiving photon IMRT," says senior author Robert Foote, M.D., a radiation oncologist at Mayo Clinic. "Our findings suggest that the theoretical advantages of proton beam therapy may in fact be real."

Researchers reviewed studies of nasal cavity and paranasal sinus tumors through extensive database searches. They included studies of patients who had no previous treatment neither primary radiation therapy nor adjuvant radiation therapy -- and patients who had recurrent disease. Researchers collected data on overall survival, disease-free survival, and tumor control, at five years and at the patient's longest follow-up. They used random-effect models to pool outcomes across studies and compared event rates of combined outcomes for proton therapy and IMRT using an interaction test.

Researchers found disease free survival to be significantly higher at five years for patients receiving proton therapy than for patients receiving IMRT (72% versus 50%). Tumor control did not differ between treatment groups at five years however tumor control was higher for patients receiving proton therapy than for IMRT at the longest follow-up (81% versus 64%).


'/>"/>

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. Mayo Clinic: Ovarian cancer subtypes may predict response to bevacizumab
2. Mayo Clinic: Drug induces morphologic, molecular and clinical remissions in myelofibrosis
3. Mayo Clinic: Add bone deterioration to diabetes complications
4. Mayo Clinic: Researchers to study bodys defense system to find new treatments for Alzheimers
5. Mayo Clinic: Less-invasive option as effective as esophagus removal in early esophageal cancer
6. Mayo Clinic: Enhanced recovery pathway for gynecologic surgery gets patients back to health faster
7. Mayo Clinic: Preclinical tests may lead to new approach to treat CNS lymphoma
8. Mayo Clinic: Rotavirus vaccine given to newborns in Africa is effective
9. Mayo Clinic: How gold nanoparticles can help fight ovarian cancer
10. Mayo Clinic: Inflammatory bowel disease raises risk of melanoma
11. Mayo Clinic: Scheduled imaging studies provide little help detecting relapse of aggressive lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2017)... ... May 22, 2017 , ... WeightZone Factor ... to empower WeightZone Factor members to track their exercise patterns, monitor behavioral changes, ... education, all on their mobile phones. It also provides social networks for members ...
(Date:5/21/2017)... ... May 20, 2017 , ... Pixel ... created specifically for use in Final Cut Pro X. The business-oriented elements and ... Pixel Film Studios’ ProParagraph Corporate will deliver a professional and distinguished look to ...
(Date:5/21/2017)... ... May 21, 2017 , ... Following the tragic and widely ... the first state to require that hospitals follow a protocol to quickly identify and ... community as to whether such steps would have saved Rory or anyone else’s life. ...
(Date:5/19/2017)... Mo (PRWEB) , ... May 19, 2017 , ... When ... May 20, his name will already appear on two major research studies that could ... been working with Dr. Matt Daggett, KCU alumnus and an orthopedic surgeon, alongside an ...
(Date:5/19/2017)... (PRWEB) , ... May 19, 2017 , ... ... containerization, today announced a sponsorship and speaking session at the 7th Annual ... the longest-running hosted enterprise mobility and digital transformation conference whose expressed purpose is ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)...  May is Stroke Awareness Month and Omron Healthcare ... methods to prevent a stroke: monitor and manage your ... and Prevention, undetected and uncontrolled hypertension is a leading ... leader in personal heart health technology, recently evolved its ... and stroke and is advancing a national public education ...
(Date:5/4/2017)... -- Fortuna Fix Inc. (" Fortuna "), a private, clinical-stage ... the need for embryonic and fetal stem cells by using ... Fortuna announced today the launch of its ... MD, PhD; Father Kevin FitzGerald , S.J., PhD; Col. ... James Giordano , PhD. "We are excited and ...
(Date:5/4/2017)... May 4, 2017 Clarius Mobile Health, ... handheld ultrasound scanners this week at the American ... (ACOG) in San Diego, CA ... "Clarius is the perfect tool for clinicians to ... rate, and evaluate pregnancy-related complications like ectopic pregnancy ...
Breaking Medicine Technology: