Navigation Links
Mayo Clinic: Less invasive surgery detects residual breast cancer in lymph nodes after chemotherapy
Date:12/5/2012

ROCHESTER, Minn. Most patients whose breast cancer has spread to their lymph nodes have most of the lymph nodes in their armpit area removed after chemotherapy to see if any cancer remains. A study conducted through the American College of Surgeons Oncology Group and led by Judy Boughey, M.D. a breast surgeon at Mayo Clinic shows that a less invasive procedure known as sentinel lymph node surgery successfully identified whether cancer remained in lymph nodes in 91 percent of patients with node-positive breast cancer who received chemotherapy before their surgery. In sentinel lymph node surgery, only a few lymph nodes, the ones most likely to contain cancer, are removed. The findings are being presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.

"Since treatment with chemotherapy before surgery can eliminate cancer in the lymph nodes in some patients, we were interested in evaluating whether sentinel lymph node surgery could successfully identify whether cancer remained in the lymph nodes after chemotherapy," says Dr. Boughey. Removing only a few lymph nodes reduces the risk of surgical complications such as numbness and arm swelling, she says.

Researchers studied 756 women with node-positive breast cancer who received chemotherapy as an initial treatment. Of study participants, 637 patients had both sentinel lymph node and axillary lymph node surgery. Sentinel lymph node surgery correctly identified whether cancer lingered in 91 percent of patients, including 255 patients with node-negative breast cancer and 326 patients with continuing node-positive disease.

Researchers also found that 40 percent of the patients had complete eradication of the cancer from the lymph nodes. The study had a false-negative rate of 12.6 percent and the false negative rate was significantly lower with the use of dual tracers (blue dye and radiolabeled colloid) to identify the sentinel lymph nodes.

Dr. Boughey says that technical factors in surgery are important to help ensure correct staging, the process of determining how far cancer may have spread.


'/>"/>

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Mayo Clinic: Obesity epidemic fueling rise in rheumatoid arthritis among women
2. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
3. Mayo Clinic: Standard heart disease risk tools underrate danger in rheumatoid arthritis
4. Mayo Clinic: Molecule thought cancer foe actually helps thyroid tumors grow
5. Mayo Clinic: Common blood pressure drug linked to severe GI problems
6. Mayo Clinic: Drug duo turns on cancer-fighting gene in kidney, breast cancers
7. Mayo Clinic: Diabetes can be controlled in patients after pancreas removal
8. Mayo Clinic: Antidepressant eases radiation-related mouth pain in head, neck cancer
9. Routine mammograms may result in significant overdiagnosis of invasive breast cancer
10. Invasive heart test being dramatically overused, Stanford study shows
11. Lower Risk for Bowel Obstruction With Less Invasive Surgery: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... , ... February 22, 2017 , ... ... and the number of African American/Black students who want to become physicians. PMF ... pursue their careers as physicians in the Oakland/San Francisco Northern California, Bay Area. ...
(Date:2/21/2017)... ... February 21, 2017 , ... Hanna Boys Center ... will be the keynote speaker at its second Professional Networking Breakfast on March ... which develops comprehensive strategies to create and expand opportunities for boys and young ...
(Date:2/21/2017)... ... February 21, 2017 , ... Ray Insurance Agencies, a Dallas area ... Tarrant County, is embarking on a six month charity event aimed at raising local ... , Cancer is one of the deadliest diseases in America; more than 7.5 million ...
(Date:2/21/2017)... Michigan (PRWEB) , ... February 21, 2017 , ... ... to the United States during Black History Month (officially African American History ... to many fields of American society of a diverse race of people, but ...
(Date:2/21/2017)... CA (PRWEB) , ... February 21, 2017 , ... A ... data on gastric balloons for weight loss. It found that the treatments have led ... of obese patients, when compared to unassisted efforts. It also noted very few problematic ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... , Feb. 22, 2017 Henry ... an exclusive distribution agreement with Rijuven, which develops ... diagnostic device to medical practitioners. ... electrocardiogram (ECG) and heart sound signals, transmits real-time ... and offers cloud-based analysis to help physicians provide ...
(Date:2/22/2017)... -- Bioness, Inc., the leading provider of cutting edge, clinically ... successful StimRouter Neuromodulation System implantations in Europe ... Netherlands ), South Victoria ... Kliniek Park Leopold Chirec ( Brussels, Belgium ... further support clinicians across the continent who are looking ...
(Date:2/22/2017)... , Feb. 22, 2017 Oncternal Therapeutics, ... for both rare and common malignancies, today announced ... financing. The company intends to use the proceeds ... TK216, and to advance preclinical development of a ... Cirmtuzumab is a first-in-class anti-ROR1 monoclonal antibody being ...
Breaking Medicine Technology: