Navigation Links
Mayo Clinic: Less invasive surgery detects residual breast cancer in lymph nodes after chemotherapy
Date:12/5/2012

ROCHESTER, Minn. Most patients whose breast cancer has spread to their lymph nodes have most of the lymph nodes in their armpit area removed after chemotherapy to see if any cancer remains. A study conducted through the American College of Surgeons Oncology Group and led by Judy Boughey, M.D. a breast surgeon at Mayo Clinic shows that a less invasive procedure known as sentinel lymph node surgery successfully identified whether cancer remained in lymph nodes in 91 percent of patients with node-positive breast cancer who received chemotherapy before their surgery. In sentinel lymph node surgery, only a few lymph nodes, the ones most likely to contain cancer, are removed. The findings are being presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.

"Since treatment with chemotherapy before surgery can eliminate cancer in the lymph nodes in some patients, we were interested in evaluating whether sentinel lymph node surgery could successfully identify whether cancer remained in the lymph nodes after chemotherapy," says Dr. Boughey. Removing only a few lymph nodes reduces the risk of surgical complications such as numbness and arm swelling, she says.

Researchers studied 756 women with node-positive breast cancer who received chemotherapy as an initial treatment. Of study participants, 637 patients had both sentinel lymph node and axillary lymph node surgery. Sentinel lymph node surgery correctly identified whether cancer lingered in 91 percent of patients, including 255 patients with node-negative breast cancer and 326 patients with continuing node-positive disease.

Researchers also found that 40 percent of the patients had complete eradication of the cancer from the lymph nodes. The study had a false-negative rate of 12.6 percent and the false negative rate was significantly lower with the use of dual tracers (blue dye and radiolabeled colloid) to identify the sentinel lymph nodes.

Dr. Boughey says that technical factors in surgery are important to help ensure correct staging, the process of determining how far cancer may have spread.


'/>"/>

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Mayo Clinic: Obesity epidemic fueling rise in rheumatoid arthritis among women
2. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
3. Mayo Clinic: Standard heart disease risk tools underrate danger in rheumatoid arthritis
4. Mayo Clinic: Molecule thought cancer foe actually helps thyroid tumors grow
5. Mayo Clinic: Common blood pressure drug linked to severe GI problems
6. Mayo Clinic: Drug duo turns on cancer-fighting gene in kidney, breast cancers
7. Mayo Clinic: Diabetes can be controlled in patients after pancreas removal
8. Mayo Clinic: Antidepressant eases radiation-related mouth pain in head, neck cancer
9. Routine mammograms may result in significant overdiagnosis of invasive breast cancer
10. Invasive heart test being dramatically overused, Stanford study shows
11. Lower Risk for Bowel Obstruction With Less Invasive Surgery: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... , ... June 28, 2017 , ... American Farmer proudly ... episode of the award winning television series, scheduled to broadcast fourth quarter 2017. American ... originated as a regional supplier of garden pea seed. As demand grew, the small ...
(Date:6/28/2017)... ... June 28, 2017 , ... Designers ... to communities in northern Virginia and DC, is announcing a cooperative charity event ... with Alzheimer’s and other disorders that lead to memory impairment. , The Insight ...
(Date:6/27/2017)... ... ... Harbour , a DAO (decentralized autonomous organization) that harnesses the wisdom ... technical specifications . , 2017 has seen an explosion of token launches by ... offerings will garner the greatest ROI. Dean Eigenmann, Co-founder and CEO of Harbour, said, ...
(Date:6/27/2017)... ... 2017 , ... A January 18th article on medGadget reports that ... by the year 2024 according to a new report. The article also notes that ... titanium. Los Angeles area clinic Beverly Hills Periodontics & Dental Implant Center says that ...
(Date:6/27/2017)... London, CT (PRWEB) , ... June 27, 2017 ... ... the Alice P. Fabrykiewicz Scholarship Foundation Fundraiser hygiene symposium in Mystic, CT. Covering ... Toback and Urbanski offered their experience in these popular periodontal procedures. Drs. Toback ...
Breaking Medicine News(10 mins):
(Date:6/12/2017)... Kineta, Inc., a biotechnology company focused on the ... President of R&D and Head of Virology Kristin Bedard has ... the Northwest and Beyond meeting sponsored by Life Science ... from 8:30-10:30 AM PDT at the Agora Conference Center in ... Bedard will be joined by other leaders in infectious disease ...
(Date:6/9/2017)... and INDIANAPOLIS , June ... are living with diabetes. In a further effort to ... people affected by this condition, the International Diabetes Federation ... LLY ) have come together for the second phase ... and Systems programme (BRIDGES 2), reaffirming their commitment to ...
(Date:6/7/2017)... DUBLIN , June 7, 2017 Endo ... on June 7, 2017, the Hon. Joseph R. ... District of West Virginia , entered ... Systems, Inc. Pelvic Repair System Products Liability Litigation (the ... filed MDL cases to provide expert disclosures on specific ...
Breaking Medicine Technology: