Navigation Links
Mayo, UCSF team discovers genomic variant that increases risk of brain tumors
Date:8/26/2012

ROCHESTER, Minn. -- People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found. The findings, published online today in the journal Nature Genetics, could help researchers identify people at risk of developing certain subtypes of gliomas which account for about 20 percent of new brain cancers diagnosed annually in the U.S. and may lead to better surveillance, diagnosis and treatment.

Researchers still have to confirm whether the spot is the source of tumors, but if it's not, "it is pretty close," says senior author Robert Jenkins, M.D., Ph.D., a pathologist at the Mayo Clinic Cancer Center. "Based on our findings, we are already starting to think about clinical tests that can tell patients with abnormal brain scans what kind of tumor they have, just by testing their blood."

A few years ago, researchers began hunting for regions of the genome that might be associated with the development of gliomas. These groups observed a portion of chromosome 8 that contained single nucleotide polymorphisms or "SNPs" associated with brain tumors. Since then, Dr. Jenkins and Margaret Wrensch, Ph.D., professor of neurological surgery at the University of California, San Francisco, have been using a combination of sophisticated genomic techniques to search for the SNP causing brain tumors to form.

They honed in on seven candidates. One -- the SNP called
'/>"/>

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. IBN discovers human neural stem cells with tumor targeting ability
2. Rutgers team discovers novel approach to stimulate immune cells
3. UZH research team discovers the origins of key immune cells
4. Yale team discovers how stress and depression can shrink the brain
5. Following the genomic pathways to stop the spread of cancer
6. Genomic study of rare childrens cancer yields possible prognostic tool
7. Genetic variants, tobacco exposure and lung cancer risk
8. Moffitt Cancer Center study validates activity of rare genetic variant in glioma
9. Tuberculosis increases the risk of lung cancer mortality in the elderly
10. Bend Research increases hot-melt extrusion capacity
11. Despite less play, childrens use of imagination increases over 2 decades
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... News) -- U.S. military troops deployed to sunny climates ... to a new study. Many returning troops ... some cases, military personnel developed blisters on their skin ... size of their moles since being deployed overseas. ... skin cancer, the study authors noted. "The past ...
(Date:9/19/2014)... News) -- Pregnant women who live in leafy, green neighborhoods ... babies, a new study suggests. Researchers analyzed data from ... expectant mothers who lived in a neighborhood with plenty of ... risk of very preterm birth (before 30 weeks) and a ... 36 weeks). Babies born to mothers who lived in ...
(Date:9/19/2014)... The U.S. Food and Drug Administration approved a new type ... a class of once-a-week injectable drugs that help manage blood ... "Trulicity is a new treatment option, which can be used ... sugar levels in the overall management of type 2 diabetes," ... Drug Evaluation II, said in an agency news release. ...
(Date:9/19/2014)... 2014 The Alliance for Bangladesh ... the National Fire Protection Association (NFPA), a recognized ... today in a Memorandum of Understanding signed by ... and other stakeholders with information, guidance and access ... health and safety of workers in ready-made garment ...
(Date:9/19/2014)... (PRWEB) September 19, 2014 MetroMD, a leading ... the “God Particle” of human health. This therapy has grown ... making the therapy more effective, safe and dependable. It has ... them an opportunity to live a very healthy and active ... concept of HGH therapy, a senior therapist at MetroMD said, ...
Breaking Medicine News(10 mins):Health News:Some U.S. Troops May Face Greater Skin Cancer Risk 2Health News:Do Greener Neighborhoods Produce Healthier Babies? 2Health News:FDA Approves Another Weekly Injectable Drug for Type 2 Diabetes 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 3Health News:MetroMD Announces Better HGH Therapy - the ‘God Particle’ of Human Health 2
... , FRIDAY, July 15 (HealthDay News) -- In an attempt ... of governments have raised taxes on cigarettes, yet many people ... Canadian study. But the public health measure has prompted ... researchers recently reported in the International Journal of Environmental ...
... In a study, Identification of unrecognized diabetes and pre-diabetes ... issue of the Journal of Dental Research, ... that dental visits represented a chance to intervene in ... pre-diabetes who are unaware of their condition. The study ...
... sizes usually mean we eat more food, but according to ... bigger bites lead to eating lessin restaurant settings. "In ... bite-sizes on overall quantity of food consumed," write authors Arul ... Utah, Salt Lake City). The authors conducted a field ...
... HealthDay Reporter , THURSDAY, July 14 (HealthDay News) -- ... the immune system,s response to HIV, the AIDS virus, in ... a vaccine. The findings won,t have an immediate big ... do reveal how soldiers of the immune system known as ...
... five to ten percent of patients with primary ... such as headaches, seizures, confusion, difficulty swallowing and ... life-threatening form of brain invasion from cancer called ... University of California, San Diego School of Medicine ...
... This release is available in German . ... Max Planck Institute for Dynamics and Self-Organization (Gttingen, Germany), ... de Lyon (France), the University Medicine Gttingen (Germany), the ... de Nice (France) have developed a new low-energy method ...
Cached Medicine News:Health News:Cigarette Tax Unlikely to Deter Some Smokers: Report 2Health News:Dentists can identify people with undiagnosed diabetes, Columbia researchers show 2Health News:Size matters: Why do people eat less when they have big forks? 2Health News:Antibody Finding Might Help in Search for HIV Vaccine 2Health News:Novel combined therapy extends life, diminishes pain in brain cancer patients 2Health News:A 'LEAP' in controlling cardiac fibrillation 2Health News:A 'LEAP' in controlling cardiac fibrillation 3
(Date:9/19/2014)... Research and Markets has announced the addition of the ... Disorder) Market - Forecast to 2023" report to their ... human microbiome market is segmented by application, disease, product, and ... be valued as $294 million in 2019 and is poised ... period of 2019-2023. The market is driven by growing incidences ...
(Date:9/19/2014)... 19, 2014 UBM Medica US announces that  ... community to help oncologists and other clinicians gain a ... use of targeted therapies and immunotherapies, discusses some of ... Every September, Blood Cancer Awareness ... awareness about blood cancers—helping to increase survival rates and ...
(Date:9/19/2014)...  Alere Inc. (NYSE: ALR ), a ... today in support of President Barack Obama,s ... global leader in rapid diagnostics for infectious disease, we ... address the serious threat of antibiotic resistance. We look ... initiatives to promote the development of rapid point-of-care tests ...
Breaking Medicine Technology:Global Human Microbiome (Diabetes, Obesity, Autoimmune, Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023 2Global Human Microbiome (Diabetes, Obesity, Autoimmune, Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023 3OncoTherapy Network Highlights National Blood Cancer Awareness Month 2OncoTherapy Network Highlights National Blood Cancer Awareness Month 3OncoTherapy Network Highlights National Blood Cancer Awareness Month 4Alere Applauds President's Executive Order Combating Antibiotic-Resistant Bacteria 2
... are part of the Freedom Urinary ... leg bags, kits, and accessories designed ... our customers. These leg bags are ... of 100% latex-free soft, textured medical ...
... are part of the Freedom Urinary ... leg bags, kits, and accessories designed ... our customers. These leg bags are ... of 100% latex-free soft, textured medical ...
The latex-free, PVC-free Antibacterial Hydro Personal catheter combines two remarkable innovations into one exclusive catheter that delivers an antibacterial agent while providing the virtually frict...
The latex-free, PVC-free Antibacterial Hydro Personal catheter combines two remarkable innovations into one exclusive catheter that delivers an antibacterial agent while providing the virtually frict...
Medicine Products: