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Mathematical modeling predicts response to Herceptin
Date:7/28/2009

ative PTEN protein expression was a key determinant of who would be resistant or sensitive to Herceptin.

Furthermore, using the mathematical modeling techniques, the absence of PTEN was more predictive than could be determined using standard multivariate or laboratory analysis.

"This paper is a major step forward because as revolutionary as Herceptin has been, there are many patients who fail. This helps us understand why and it would not have been possible without the new mathematical techniques," said Merajver.


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Contact: Jeremy Moore
jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

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