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Math from the heart: Simulating stent design and coating
Date:8/23/2010

So Canic is using her computer programs to simulate how blood interacts with the stent-coating cartilage cells and how the cells stick (or don't) to the stent surface. She plugs in different fluid thicknesses and shear forces of blood flowing over the stent to see what might encourage the cartilage on freshly coated stents to stabilize quickly. The models have helped her collaborators home in on the best conditions to test in follow-up experiments as they search for ways to pre-treat stents before doctors implant them.

Canic wants to keep collaborating with the medical community as she moves forward with her research. She plans to look at biodegradable stents, as well as simulate the fluid dynamics of regurgitating mitral valves (where some blood flows backwards in the pumping heart) to help doctors more accurately diagnose the condition using ultrasound.

"Certainly I am going to continue working in this area," she says. "It is very rewarding."


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Contact: Emily Carlson
carlsone@nigms.nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
Source:Eurekalert  

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