Navigation Links
Master molecular switch may prevent the spread of cancer cells to distant sites in the body
Date:3/16/2009

cated those cDNAs that produced proteins that promoted the epithelial splicing program. It was from this screen that ESRP1 and ESRP2 emerged.

In ongoing work, the team found that ESRP1 and ESRP2 are critical for epithelial-specific splicing of many other genes in addition to FGFR2. Several of the proteins made from these RNAs also have different functions that either help cells to stay attached in place or to promote local invasion of cancer cells that are capable of traveling to distant sites. The team is also engineering mice in which the genes for ESRP1 and 2 can be selectively "knocked-out" so that they can further study the importance of these two proteins during development as well as in disease. In addition, studies are planned to use the same splicing reporter system to screen for drugs that might restore the epithelial pathway and interfere with metastasis and fibrosis.


'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. McMaster study sheds light on how stem cells develop into blood cells
2. LifeMasters Introduces Health Activation Tool to Disease Management Participants
3. LifeMasters Offers Financial Incentives to Florida Physicians for Participation in Disease Management Programs
4. Benedictine University Launches New Online Program, Master of Science in Nursing
5. Benedictine University Launches New Online Program, Master of Science in Nursing
6. Research Shows Successful Physician Engagement in LifeMasters Disease Management Programs
7. Henry Mayo Newhall Memorial Hospital to Proceed With Master Plan
8. Linemaster Switch Corporation Exhibiting at MEDICA 2008
9. New laser method reproduces art masterworks to protein patterns
10. LifeMasters Receives Full Accreditation for Disease Management Programs
11. Capella University Offers New MS in Psychology Specialization in Child and Adolescent Development : Capella is the only regionally accredited online university to offer this master's specialization
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Master molecular switch may prevent the spread of cancer cells to distant sites in the body
(Date:9/2/2014)... news release is available in Spanish . ... Granada have found, through an experiment conducted on rats, that ... of great use for groups with bone disease problems, such ... also revealed that vegetal proteinin the case of the present ... protein), since the former increased the level of calcium in ...
(Date:9/2/2014)... Somerset, N.J. (PRWEB) September 02, 2014 ... delivery technologies and development solutions for drugs, biologics ... support of its strategic partner, Eli Lilly’s growth, ... clinical packaging lines at its Philadelphia Clinical Supply ... prefilled syringe packaging capabilities in its clinical supply ...
(Date:9/2/2014)... Australia (PRWEB) September 02, 2014 The ... has fluctuated over the past five years. Industry revenue ... of 1.0% over the five years through 2014-15, following ... have faced increasing external competition from alternate forms of ... and other online gambling platforms have all become increasingly ...
(Date:9/2/2014)... Based on new studies, concerns ... kidney and spleen surgeries, have continued to mount. ... patients. , An article in the "Public ... Titilope Oduyebo and Bradley J. Quade called, "Peritoneal ... on Nov 26, 2012 defines a morcellator ...
(Date:9/2/2014)... 2014 (HealthDay News) -- When it comes to excess pounds ... a new study finds. The research found that belly ... odds for high blood pressure more than overall body fat. ... high blood pressure. But it wasn,t clear how the location ... researchers at University of Texas Southwestern Medical Center in Dallas. ...
Breaking Medicine News(10 mins):Health News:Study conducted on rats suggests that hyperproteic diets can be beneficial for bones 2Health News:Catalent Supports Eli Lilly's Growing Global Clinical Trials Needs with New Investment in Automated Packaging Solutions 2Health News:Lotteries in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Lotteries in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:New York Law Firm Discusses Allegedly Dangerous Surgical Morcellator Devices And Cancer Risk 2Health News:New York Law Firm Discusses Allegedly Dangerous Surgical Morcellator Devices And Cancer Risk 3Health News:'Spare Tire' May Be Especially Bad for Your Blood Pressure 2
... simple blood test corresponding to the follicular phase (days ... optimal scheduling of breast MRI exams in premenopausal women ... repeat scans and non-diagnostic tests patients experience and providing ... to a study published in the December issue of ...
... Nov. 20 As more red flags are uncovered about ... played a significant role in enabling this to happen. Has ... of inclusion and acceptance into a dangerous unwillingness to acknowledge ... and author Dr. Gaby Cora asserts that dangerous behavior in ...
... , Unique Survey Takes First-Time Look at Employers, ... 20 More employers are taking steps to improve their ... prescribed, a move that could stave off more serious and ... the National Pharmaceutical Council (NPC). , Medication compliance, sometimes ...
... Keep your children ... Kiley. , ... 2009 -- During the exciting weeks leading up to the holidays, many people find themselves ... the spirit of the season. Among all this holiday cheer we often forget that unsafe ...
... ... a line of pacifiers affixed to stuffed animals, she not only thought she created ... years later, apparently someone else thought so as well, as Williams was one of ... , ...
... WOONSOCKET, R.I., Nov. 20 CVS/pharmacy kicks off its annual ... St. Jude Children,s Research Hospital Thanks and Giving ... CVS/pharmacy store colleagues will encourage customers to add $1 to ... of St. Jude, one of the world,s premier centers for ...
Cached Medicine News:Health News:Psychiatrist Says Political Correctness Is Costing Lives 2Health News:Medication Compliance Is a Key Concern for Employers, According to New Survey 2Health News:Medication Compliance Is a Key Concern for Employers, According to New Survey 3Health News:Parents: Holiday Safety Tips from Massachusetts Child Injury Lawyer Thomas M. Kiley 2Health News:Parents: Holiday Safety Tips from Massachusetts Child Injury Lawyer Thomas M. Kiley 3Health News:Pacimals Founder Recognized in Time Magazine's "Inventors and Their Inventions" Special Section 2Health News:CVS/pharmacy Kicks Off Annual Thanks and Giving(R) Campaign for the St. Jude Children's Research Hospital 2
(Date:9/2/2014)... , Sept. 2, 2014  Cyberonics, Inc. ... from the ANTHEM-HF clinical study.  Results of the ... during a major European cardiology congress and concurrently ... show Autonomic Regulation Therapy (ART) in patients ... impaired heart function is safe, improves the heart,s ...
(Date:9/2/2014)... Calif. , Sept. 2, 2014  Abaxis, Inc. ... manufacturing point-of-care blood instrumentation and consumables to the medical, ... Severson , Chairman and Chief Executive Officer, will present ... September 10, 2014 at 10:20 a.m. ET. The conference ... in New York City . ...
(Date:9/2/2014)... , Sept. 2, 2014  Hologic, Inc. (NASDAQ: ... and Chief Executive Officer, will present at the Morgan Stanley ... , New York on Tuesday, September ... parties are invited to listen to the live audio webcast ... at www.hologic.com/investors-overview . An archive of the presentation will ...
Breaking Medicine Technology:ANTHEM-HF Shows Autonomic Regulation Therapy Is Safe And Improves Heart Function In Patients With Chronic Heart Failure 2ANTHEM-HF Shows Autonomic Regulation Therapy Is Safe And Improves Heart Function In Patients With Chronic Heart Failure 3ANTHEM-HF Shows Autonomic Regulation Therapy Is Safe And Improves Heart Function In Patients With Chronic Heart Failure 4ANTHEM-HF Shows Autonomic Regulation Therapy Is Safe And Improves Heart Function In Patients With Chronic Heart Failure 5Abaxis, Inc. to Present at the Morgan Stanley Global Healthcare Conference 2
... MADISON, Wis., Aug. 8, 2011 Symphony Corporation, ... the acquisition of JGI, a New Jersey-based Human ... significant presence in the healthcare industry nationally.  Symphony,s ... its offerings to provide the highest level of ...
... DIEGO, Aug. 8, 2011 HUYA Bioscience International, a ... strategic partnership with the Shanghai Jiao Tong University School ... assist King,s Lab in accelerating the development of their ... provides HUYA with access to and first review of ...
Cached Medicine Technology:Symphony Corporation Acquires JGI to Provide End-to-End Services for Healthcare IT 2HUYA Bioscience International and Shanghai Jiao Tong University King's Lab Form Alliance 2HUYA Bioscience International and Shanghai Jiao Tong University King's Lab Form Alliance 3
... Wheaton Harness™ A Pavlik-type harness with ... the treatment of congenital hip dysplasia. ... lining, and antislip foot pieces.,Color-coded anterior ... adjustments can be made while the ...
... cost walker features a non-skid rocker outsole ... profile design minimizes leg length discrepancy. Three ... strapping quick and easy. Steel uprights are ... ankle and bulky bandaging. Designed for easy ...
... walker provides comfortable stability for acute ankle ... leg, stress fractures of the lower leg ... ankle. Extension pads for the liner are ... Tide walker with midcalf uprights, is ideal ...
... Cronin, Inc. is a ... Footwear, Orthopedic Softgoods, and ... Our products are of ... available in the USA ...
Medicine Products: