Navigation Links
Mass. General enters collaboration to develop new approach to capturing circulating tumor cells
Date:1/3/2011

Massachusetts General Hospital (MGH) has entered into a collaborative agreement with Veridex LLC to establish a center of excellence in research on circulating tumor cell (CTC) technologies. The overall goal of the agreement is to develop and commercialize novel technologies for capturing and characterizing CTCs, solid tumor cells found at extremely low levels in the bloodstream, which may offer a key to noninvasive characterization of cancer and potentially to early detection.

The collaboration will bring technology innovation experts from the MGH BioMicroElectroMechanical Systems (BioMEMS) Resource Center and molecular biologists and clinical researchers from the MGH Cancer Center together with research and development staff at Veridex, who have experience in clinical validation and regulatory clearance of novel technology, and at the Ortho Biotech Oncology R&D Unit of Johnson & Johnson Pharmaceutical Research, L.L.C., who have expertise in oncology therapeutics, biomarkers and companion diagnostics. The MGH team has already developed a microfluidic chip capable of capturing CTCs with a high rate of efficiency. However the technology now being developed with the companies is based on a new technological platform and will aim for even higher sensitivity, as well as suitability for broad applications and ready dissemination.

"This agreement is quite different from the usual academic-industrial agreement because we will be working together to bring new MGH-invented technology from its current, very early stage, through prototype and scale-up, to our ultimate goals of FDA approval and clinical adoption," says Mehmet Toner, PhD, director of the MGH BioMEMS Resource Center. "Our innovation team will be dedicated to developing this technology from its basic scientific principles all the way to initial prototyping within the biological research and clinical environments. Veridex has the knowledge required to translate early-stage technology into a product that can be reliably manufactured and meet regulatory requirements.

"Applying data gathered from CTCs to the care of cancer patients is a complex problem, and our strategy is to diversify technological approaches to find the best solutions for specific applications," Toner adds. "We may find that different technologies work better for diagnosis, for prognosis and for the long-term goal of early detection; so we don't want to confine ourselves to a single option." His team is continuing to develop the microfluidic chip technology, with the support of Stand Up to Cancer.

Daniel Haber, MD, PhD, director of the MGH Cancer Center, says, "The ability to establish a dedicated MGH research center focused on the intersection of bioengineering, molecular biology and clinical oncology presents an opportunity to develop a next-generation platform that will help us detect, define and monitor cancer cells more effectively which should make an enormous difference in the lives of so many patients and their families."


'/>"/>

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital
Source:Eurekalert

Related medicine news :

1. Mass. doctor invents product to curb hospital-acquired infections
2. Researchers to study effects of Mass. health reform
3. Mass. General Hospital, Iacocca Foundation announce completion of Phase I diabetes trial
4. Mass. Eye and Ear receives NEI grant renewal for growing clinical/scientists
5. Mass. General Hospital to create registry for coronary optical coherence tomography
6. Coma and general anesthesia demonstrate important similarities
7. AGA, General Mills announce grant to uncover role between intestinal bacteria and health and disease
8. Even One Cigarette Can Prove Lethal, U.S. Surgeon General Says
9. Statins dont prove useful for general pediatric lupus population
10. U.S. Hispanics Outlive General Population: CDC
11. High Blood Sugar Levels Increase Infection Risk From General Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... ... February 23, 2017 , ... Los Angeles-based weight loss ... WE TV’s “Mama June: From Not to Hot,” which will begin airing on February ... Shannon, known to millions from the 2012 reality television series, “Here Comes Honey Boo ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... Dr. David ... in Henderson, NV 89052. Dr. Mahon was named a 2017 Top Patient Rated ... is an online directory that recognizes local physicians and dentists who have earned ...
(Date:2/23/2017)... ... February 23, 2017 , ... The Center for ... Island Consortium for Autism Research and Treatment (RI-CART) and Cinemaworld to present Sensory ... disorder (ASD) to see films in an environment that accommodates their unique needs. ...
(Date:2/23/2017)... ... February 23, 2017 , ... HealthPostures, the desk for ... expert sit stand solutions representative to the Minneapolis Home and Garden Show which is ... event that is garnering national attention is the Minneapolis Convention Center. , From ...
(Date:2/22/2017)... ... February 22, 2017 , ... Gevir, a New Zealand-based company ... announced its products are coming soon to Amazon.com, the world’s largest online retailer. ... a means to develop an effective natural treatment for Shelley’s Multiple Sclerosis, which she’d ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)...  Cogentix Medical, Inc. (NASDAQ: CGNT), a medical device ... for the urology market, will release financial results for ... 2016 before the market open on Thursday, March 9, ... conference call and webcast to discuss its financial results ... 11:00 a.m. Eastern Time (10:00 a.m. Central Time). ...
(Date:2/23/2017)... 23, 2017 Research and Markets has announced ... Strategies - 2016" report to their offering. ... The latest research Oesophageal Cancer ... and benchmarks in the global Oesophageal Cancer market. The ... are the key drugs marketed for Oesophageal Cancer and their clinical ...
(Date:2/23/2017)... , February 23, 2017 ... Market by Product (X-ray Imaging Digital, Analog), MRI (Closed, ... (OB/GYN, MSK, Cardiology, Oncology), End User (Hospitals, Imaging Centers) ... report studies the global market over the forecast period ... reach ~USD 36.43 Billion by 2021, at a CAGR ...
Breaking Medicine Technology: