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Mass. General Hospital to create registry for coronary optical coherence tomography
Date:3/25/2010

States and was a forum for physicians to share the latest work in the field. International sites will begin enrolling patient in the MGH OCT Registry in June. Enrollment in the United States will begin pending clearance of OCT by the U.S. Food and Drug Administration.

OCT technology offers the promise of visualizing the microscopic characteristics of a vulnerable plaque such as a large lipid pool covered by a thin fibrous cap by creating extremely high-resolution images from within the coronary artery. Using near-infrared light, OCT bounces light off the vessel wall and collects details down to 10 microns, a resolution at least 20 times better than computed tomography. The resulting image of the coronary artery captured in a matter of seconds offers a clear depiction of the plaque's architecture.

In addition to its potential for identifying vulnerable plaques, the technology may also be used to determine optimal stent placement. In Japan, OCT imaging is a standard follow up to stenting procedures to determine if the stent has effectively widened the affected artery and the area is free of blood clots.

"The development of OCT and its rapid adoption for intravascular imaging is enabling the ability of clinicians to capture in vivo what was previously seen only through a pathologist's microscope," says Jang. "Of course, the long-term goal is to identify plaques and prevent sudden cardiac death and heart attacks."


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Contact: Jennifer Gundersen
jgundersen1@partners.org
617-724-6433
Massachusetts General Hospital
Source:Eurekalert

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