Navigation Links
Mass. General Hospital to create registry for coronary optical coherence tomography
Date:3/25/2010

Massachusetts General Hospital (MGH), together with a coalition of 20 international sites in five countries, will create the world's largest registry of patients who have had optical coherence tomography (OCT) of the coronary arteries. OCT is an intravascular imaging technology that researchers hope will give doctors a better means to identify the dangerous vulnerable plaques that cause heart attacks and sudden cardiac death.

When a vulnerable plaque in the coronary artery ruptures, the result for the patient can be catastrophic. Ruptured plaques can block blood flow to the heart muscle, and cardiologists estimate they cause two-thirds to three-quarters of all fatal heart attacks. Standard imaging technologies are not able to identify the microscopic characteristics of vulnerable plaques.

Twenty sites in five countries Australia, China, Japan, Korea, and the United States will collect data from 3,000 patients who have had OCT of the coronary arteries during a cardiac catheterization procedure and follow them for five years. MGH researchers will gather the data in a central database. Researchers hope the data will help determine the efficacy of OCT in identifying vulnerable plaques in patients as well as its benefits as a follow-up procedure to stent placement.

"The Massachusetts General Hospital OCT Registry is the first time an international effort has formed to share information about OCT use in cardiac care," said Ik-Kyung Jang, MD, PhD, an interventional cardiologist at MGH and the principal investigator of the project. "In 2009, more than 10,000 OCT cases were performed. This collaborative effort will bring together this wealth of information and help us facilitate scientific advancement in the field of OCT."

The registry was launched during the first MGH OCT Registry Symposium held March 13, 2010, in Boston. The symposium, sponsored by LightLab Imaging, Inc., was the first gathering of OCT experts held in the United States and was a forum for physicians to share the latest work in the field. International sites will begin enrolling patient in the MGH OCT Registry in June. Enrollment in the United States will begin pending clearance of OCT by the U.S. Food and Drug Administration.

OCT technology offers the promise of visualizing the microscopic characteristics of a vulnerable plaque such as a large lipid pool covered by a thin fibrous cap by creating extremely high-resolution images from within the coronary artery. Using near-infrared light, OCT bounces light off the vessel wall and collects details down to 10 microns, a resolution at least 20 times better than computed tomography. The resulting image of the coronary artery captured in a matter of seconds offers a clear depiction of the plaque's architecture.

In addition to its potential for identifying vulnerable plaques, the technology may also be used to determine optimal stent placement. In Japan, OCT imaging is a standard follow up to stenting procedures to determine if the stent has effectively widened the affected artery and the area is free of blood clots.

"The development of OCT and its rapid adoption for intravascular imaging is enabling the ability of clinicians to capture in vivo what was previously seen only through a pathologist's microscope," says Jang. "Of course, the long-term goal is to identify plaques and prevent sudden cardiac death and heart attacks."


'/>"/>

Contact: Jennifer Gundersen
jgundersen1@partners.org
617-724-6433
Massachusetts General Hospital
Source:Eurekalert

Related medicine news :

1. Mass. Eye and Ear Infirmary Cataract Surgery Trainer teaches residents cataract surgery
2. Miles for Hope’s Moving Towards A Cure(SM) Brain Tumor Walk in Boston Raising Funds for Brain Tumor Vaccine and Massachusetts General Hospital
3. Pennsylvania Attorney General Corbett Will File Lawsuit to Block Health Care Reform Legislation
4. Deep brain stimulation reduces epileptic seizures in patients with refractory partial and secondarily generalized seizures
5. AdvancedMD Appoints William Stone Vice President and General Manager of Billing Services Partner Program
6. Delphi Healthcare Parners Announces New General Surgery Hospitalist Program with CarolinaEast Health System in New Bern, North Carolina
7. United Nations Secretary-General Ban Ki-moon, President Bill Clinton, Launch MASSIVEGOOD, a Citizen Solution for Funding Global Health
8. General Nutrition Centers, Inc. Reports Fourth Quarter 2009 Results
9. Coffee Is Generally Heart-Friendly
10. U.S. Surgeon General Regina Benjamin to Address National Association of Black Journalists Conference on Health Disparities
11. RNs Praise Attorney General Move to Subpoena Insurance Plans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... , ... June 27, 2016 , ... Quality metrics are ... in many ways they remain in the eye of the beholder, according to experts ... publication of The American Journal of Managed Care. For the full issue, click ...
(Date:6/26/2016)... Viejo, California (PRWEB) , ... June 26, 2016 , ... ... Final Cut Pro X. , "Film editors can give their videos a whole new ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels contains ...
(Date:6/26/2016)... Charlotte, NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind ... able to be personalized through a fitness app. The fitness app plans to fix the ... solutions currently only offer a one size fits all type program , They ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/24/2016)... Tenn. , June 24, 2016  Arkis ... providing less invasive and more durable cerebrospinal fluid ... in funding.  The Series-A funding is led by ... Lighthouse Fund, and other private investors.  Arkis, new ... neurosurgical instrumentation and the market release of its ...
(Date:6/23/2016)... Research and Markets has announced ... Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality ... - Global Forecast to 2021" report to their ... global pharmaceutical excipients market is projected to reach USD ... in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: