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Markey receives $6.25 million to study deadly blood and bone marrow disease
Date:5/22/2012

roduces blood cells. Normally, the bone marrow makes blood stem cells that develop into mature blood cells over time. With MDS, the blood stem cells do not mature. These immature blood cells do not function normally and either die in the bone marrow or soon after they enter the blood. With fewer blood cells available, an infection, anemia, or easy bleeding may occur. Once MDS develops, it can progress into leukemia, and it is largely untreatable.

"At UK, our research will start with basic science and progress to translational science. One of our first steps will be to figure out what can cause these changes in bone marrow that lead to myelodysplastic syndrome," said Van Zant, professor and director of the Clinical Stem Cell Laboratory for the UK Bone Marrow Transplant Program. "From there, our focus will be how we can predict which patients may be at a higher risk to get the disease if they receive chemo or radiation, and ultimately, how we can better treat those patients who have already developed myelodysplastic syndrome."


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Contact: Allison Perry
allison.perry@uky.edu
859-323-2399
University of Kentucky
Source:Eurekalert

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