Navigation Links
Marker for Diabetes Might Miss Early Vision Complication

Eye damage begins at blood sugar levels below current threshold for diagnosis, study finds

FRIDAY, Feb. 29 (HealthDay News) -- Fasting blood sugar levels are typically used to diagnose diabetes, however, a common complication of the disease that can lead to blindness begins at blood sugar levels below what is considered diabetic, Australian researchers report.

Retinopathy is a vascular condition where the small blood vessels in the eye become damaged; other complications of diabetes include heart, kidney and circulatory problems.

"Retinopathy, which is one of the complications traditionally associated with diabetes, occurs at fasting glucose levels below the threshold that is used to define diabetes," said lead researcher Dr. Tien Y. Wong, chairman of the Department of Ophthalmology at the University of Melbourne.

In the study, Wong's team analyzed three studies that looked at retinopathy among 11,405 people. The report was published in the March 1 issue of The Lancet.

The researchers found that the overall prevalence of retinopathy ranged from 9.6 percent to 15.8 percent in the general population. In addition, they didn't find evidence of a particular blood glucose level that would indicate the presence of retinopathy. In fact, 60 percent of retinopathy cases were missed by the current threshold for diabetes diagnosis, which is 7.0 mmol/L.

The finding suggests that eye damage happens much earlier and at lower blood sugar levels than what is currently used to pinpoint the presence of diabetes, Wong said. "This suggests that diagnostic threshold may have to be revised, so that we can pick up more people who are at risk of eye and other complications," he noted.

In addition to retinopathy, signs of cardiovascular disease also appear to develop at glucose levels below those defined as diabetes, Wong said.

One expert agrees that fasting blood sugar levels may not be the best way of diagnosing diabetes and those at risk for diabetes.

"It is becoming more common that studies are showing that a fasting blood sugar value is not necessarily the best way to judge diabetes or diabetes control," said Dr. Stuart Weiss, an endocrinologist at New York University Medical Center.

Weiss noted that right now there is no other marker for diabetes. However, many new studies point to the use of blood sugar levels after eating as being better markers for risk, he said.

"Fasting blood sugar is not all that helpful," Weiss said. "The problem is that a lot of our thinking is based on fasting. That's an issue we need to focus in on," he said.

More information

For more about diabetes, visit the American Diabetes Association.

SOURCES: Tien Y. Wong, M.D., M.P.H., Ph.D., professor and chairman, Department of Ophthalmology, The University of Melbourne, Australia; Stuart Weiss, M.D., endocrinologist, New York University Medical Center, and clinical assistant professor, NYU School of Medicine, New York City; March 1, 2008, The Lancet

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Biomarkers for Mood May Alter Psychiatric Treatments
2. New blood marker may predict prostate cancer spread
3. Overweight Hispanic Kids Show Early Markers for Diabetes
4. Sigma-Aldrich Licenses From NeuroSurvival Technologies a Leading Marker for Molecular Imaging of Apoptosis in Vivo
5. UCLA researchers discover biomarkers that predict lung cancer patient response to therapy
6. Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression
7. Cancer stem cell marker also drives transcription in normal cells
8. Gene markers located for hereditary prostate cancer
9. Proteomic profiling shown more accurate than traditional biomarkers in identifying liver cancer
10. Blood Markers Might Predict Clotting Risk With HRT
11. Biological markers of prostate cancer shed light on cancer burden faced by African-American men
Post Your Comments:
Related Image:
Marker for Diabetes Might Miss Early Vision Complication
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... ... accessible for all, Water For Empowerment ™ attracts volunteers together who want ... water by empowering women as key stakeholders in the process. The non-profit launched ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... offering factory direct sauna parts and accessories. , Sauna accessories help improve the ... bather’s style and personality. From basic styles for the purist looking for simplicity ...
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert is ... One Beat ” campaign. The partnership between the two groups began in 2014 with ... International’s cause. , MAP International was founded in 1954 and is an international Christian-based ...
(Date:11/25/2015)... ... November 25, 2015 , ... On November 25, 2015, officials of Narconon ... announced the release of a new cutting edge recovery program that has been 50 ... with drug- and alcohol-addicted individuals with the purpose to free addicts from the symptoms ...
(Date:11/25/2015)... ... November 25, 2015 , ... Smiles by Stevens is ... and moderate facial wrinkling. While many patients are aware of the benefits of Botox® ... Botox® delivers to those suffering with discomfort, soreness, and pain as a result of ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in the ... Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new 247-page ... therapeutic drug monitoring market, including emerging tests, technologies, ...
(Date:11/25/2015)... SYDNEY , Nov. 26, 2015  The total global ... nearly 7% over 2015-2016. Latin America ... Asia , (excluding Japan ), is ... continues to face increased healthcare expenditure. In 2013-2014, ... expenditure declined from 43.5% in 2008-2009 to 41.2% in 2013-2014. ...
(Date:11/25/2015)... , Nov. 25, 2015 AAIPharma Services ... investment of at least $15.8  Million to expand ... Wilmington, NC . The expansion will provide ... meet the growing demands of the pharmaceutical and ... site expansion will provide up to 40,000 square ...
Breaking Medicine Technology: