Navigation Links
Marilyn B. Gula Mountains of Hope Foundation grants $100,000 to TGen
Date:11/15/2012

PHOENIX, Ariz. A gourmet culinary fte has raised $100,000 for groundbreaking breast cancer research at the non-profit Translational Genomics Research Institute (TGen).

The Marilyn B. Gula Mountains of Hope Foundation raised the $100,000 through its 2nd annual "Cookin' for a Cure at Eddie's House," a fundraising event in March at award-winning chef Eddie Matney's exclusive Scottsdale restaurant.

Mountains of Hope has donated the funds to a research project led by Dr. Heather Cunliffe, head of TGen's Breast and Ovarian Cancer Research Unit. The research will focus on a specific and difficult-to-treat type of cancer called primary Luminal B breast cancer one of at least five major subtypes of breast cancer.

"We feel confident that this project will enable Dr. Cunliffe and her team to determine the genetic variables that are driving this particular type of breast cancer," said Phoenix businessman Allen Gula Jr., Chairman of the Mountains of Hope Foundation, whose late wife Marilyn died of breast cancer in 2006 following a decade-long battle against the disease. "This research is especially important to patients with advanced breast cancer, who have fewer treatment options."

TGen's goal is to learn enough about the possible genomic causes of Luminal B breast cancer to initiate a clinical trial within 3-5 years. Luminal B tumors account for approximately 19 percent of the nearly 227,000 new cases of invasive breast cancer each year in the U.S.

"We are entering a new era of evidence-based precision therapeutics for individual patients," Dr. Cunliffe said. "The goal of a clinical trial based on this study would be to prevent disease recurrence in patients with early stage Luminal B breast cancer through the use of targeted treatments."

A major problem with this type of cancer is the tumor's resistance to conventional chemotherapy. While Luminal B tumors are fueled by estrogen, they are often not responsive to anti-estrogen drugs. The disease also has a high propensity for recurrence and often spreads to other organs in the body, which then make it very difficult to treat.

Luminal B tumors are composed of genetically distinct populations of tumor cells that are both estrogen receptor positive, and estrogen receptor negative. Researchers will test their hypothesis that the severity of genetic changes in one or both sub-populations contributes to treatment failure and poor outcome for Luminal B patients. This work will be conducted in collaboration with Dr. Michael Barrett, head of TGen's Oncogenomics Laboratory.

"At the conclusion of this study, we aim to have identified genetic abnormalities that are unique to the estrogen receptor positive and estrogen receptor negative clones within Luminal B cancers," said Dr. Cunliffe.

With this most recent gift, the Marilyn B. Gula Mountains of Hope Foundation has contributed a total of $470,000 towards Dr. Cunliffe's TGen research.

"The Mountains of Hope Foundation, led by Al Gula, has brought incredible passion, commitment and energy to TGen's fight against the most aggressive breast cancers," said Michael Bassoff, President of the non-profit TGen Foundation. "There is no question that women around the world will benefit from the research funded by their generous contributions."


'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Related medicine news :

1. Kessler Foundation scientists report negative impact of long-term caregiving on cognition
2. John Templeton Foundation grant supports Princeton neuroscientists to study cognitive control
3. Kessler Foundation stroke expert receives $145,000 grant from Healthcare Foundation of New Jersey
4. UGR and Michael J. Fox Foundation take a step forward in the study of Parkinsons disease
5. Dr. Taub to give Estabrook Research Lecture at Kessler Foundation on Nov. 28
6. Edith Sanford Breast Cancer Foundation and TSRI partner in genomic breast cancer research
7. Kessler Foundation scientists awarded New Jersey grants for brain injury research
8. Research prizes from the Carlsberg Foundation to researchers from University of Copenhagen
9. Kessler Foundation scientist garners best poster award for MS research
10. Dr. Chiaravalloti of Kessler Foundation comments on trends in rehabilitation research in MS
11. Kessler Foundation presents Brain Injury: From Research to Rebuilding Lives on Sept. 27-28
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... 2017 , ... A recent report from the National Council on Teacher Quality ... report suggests, based on a review of GPA and SAT/ACT requirements at 221 institutions ... U.S. It argues that this higher bar should be set by states, by the ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating their commitment to improving ... health departments have been awarded national accreditation through the Public Health Accreditation ... expanding network of communities across the nation whose health departments meet rigorous national ...
(Date:3/23/2017)... Montclair, NJ (PRWEB) , ... March 23, 2017 ... ... the Renaissance Oklahoma City Convention Center at 10 North Broadway Avenue, will be ... 6.0 hours of relevant, practical instruction in the management of chronic pain. , ...
(Date:3/23/2017)... PA and Grimsby, Ontario (PRWEB) , ... March 23, 2017 , ... The MBI “Hall ... modular industry or whose acts have had a significant impact on the careers of all ... and Marketing with NRB Inc. was inducted into the MBI’s Hall of Fame. The ...
(Date:3/23/2017)... ... March 23, 2017 , ... Dilger-Maxwell ... of the Norwalk and Vermillion areas, celebrates the newest charity campaign in ... nonprofit, community-based substance abuse prevention and peer recovery support organization providing vital ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , March 24, 2017 FinancialBuzz.com ... ... leading publisher of cannabis market research, the legal cannabis market ... CAGR through 2021, despite conflicting signals from the current presidential ... out that the two biggest drivers of growth in this ...
(Date:3/24/2017)... India , March 24, 2017 ... of the industry including definitions, classifications, applications and industry ... the international market including development history, competitive landscape analysis, ... ... Ampoules industry spread across 105 pages providing 10 company ...
(Date:3/24/2017)... DALLAS , March 23, 2017  HealthMine surveys ... January 2017 revealed that health plan members want help ... reason to stay engaged in their health, 2) help ... an integrated platform for health and 5) relevant, real-time ... outcomes and lowering healthcare costs. ...
Breaking Medicine Technology: