Navigation Links
Marilyn B. Gula Mountains of Hope Foundation grants $100,000 to TGen
Date:11/15/2012

PHOENIX, Ariz. A gourmet culinary fte has raised $100,000 for groundbreaking breast cancer research at the non-profit Translational Genomics Research Institute (TGen).

The Marilyn B. Gula Mountains of Hope Foundation raised the $100,000 through its 2nd annual "Cookin' for a Cure at Eddie's House," a fundraising event in March at award-winning chef Eddie Matney's exclusive Scottsdale restaurant.

Mountains of Hope has donated the funds to a research project led by Dr. Heather Cunliffe, head of TGen's Breast and Ovarian Cancer Research Unit. The research will focus on a specific and difficult-to-treat type of cancer called primary Luminal B breast cancer one of at least five major subtypes of breast cancer.

"We feel confident that this project will enable Dr. Cunliffe and her team to determine the genetic variables that are driving this particular type of breast cancer," said Phoenix businessman Allen Gula Jr., Chairman of the Mountains of Hope Foundation, whose late wife Marilyn died of breast cancer in 2006 following a decade-long battle against the disease. "This research is especially important to patients with advanced breast cancer, who have fewer treatment options."

TGen's goal is to learn enough about the possible genomic causes of Luminal B breast cancer to initiate a clinical trial within 3-5 years. Luminal B tumors account for approximately 19 percent of the nearly 227,000 new cases of invasive breast cancer each year in the U.S.

"We are entering a new era of evidence-based precision therapeutics for individual patients," Dr. Cunliffe said. "The goal of a clinical trial based on this study would be to prevent disease recurrence in patients with early stage Luminal B breast cancer through the use of targeted treatments."

A major problem with this type of cancer is the tumor's resistance to conventional chemotherapy. While Luminal B tumors are fueled by estrogen, they are often not responsive to anti-estrogen drugs. The disease also has a high propensity for recurrence and often spreads to other organs in the body, which then make it very difficult to treat.

Luminal B tumors are composed of genetically distinct populations of tumor cells that are both estrogen receptor positive, and estrogen receptor negative. Researchers will test their hypothesis that the severity of genetic changes in one or both sub-populations contributes to treatment failure and poor outcome for Luminal B patients. This work will be conducted in collaboration with Dr. Michael Barrett, head of TGen's Oncogenomics Laboratory.

"At the conclusion of this study, we aim to have identified genetic abnormalities that are unique to the estrogen receptor positive and estrogen receptor negative clones within Luminal B cancers," said Dr. Cunliffe.

With this most recent gift, the Marilyn B. Gula Mountains of Hope Foundation has contributed a total of $470,000 towards Dr. Cunliffe's TGen research.

"The Mountains of Hope Foundation, led by Al Gula, has brought incredible passion, commitment and energy to TGen's fight against the most aggressive breast cancers," said Michael Bassoff, President of the non-profit TGen Foundation. "There is no question that women around the world will benefit from the research funded by their generous contributions."


'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Related medicine news :

1. Kessler Foundation scientists report negative impact of long-term caregiving on cognition
2. John Templeton Foundation grant supports Princeton neuroscientists to study cognitive control
3. Kessler Foundation stroke expert receives $145,000 grant from Healthcare Foundation of New Jersey
4. UGR and Michael J. Fox Foundation take a step forward in the study of Parkinsons disease
5. Dr. Taub to give Estabrook Research Lecture at Kessler Foundation on Nov. 28
6. Edith Sanford Breast Cancer Foundation and TSRI partner in genomic breast cancer research
7. Kessler Foundation scientists awarded New Jersey grants for brain injury research
8. Research prizes from the Carlsberg Foundation to researchers from University of Copenhagen
9. Kessler Foundation scientist garners best poster award for MS research
10. Dr. Chiaravalloti of Kessler Foundation comments on trends in rehabilitation research in MS
11. Kessler Foundation presents Brain Injury: From Research to Rebuilding Lives on Sept. 27-28
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... , ... December 07, 2016 , ... A quote from ... outpouring of comments on social media that offer a rare glimpse into the mind ... ADHD authority and New York Times bestselling author, has described people with ADHD as ...
(Date:12/7/2016)... ... December 07, 2016 , ... The Cliff Hart ... in South Lyon, Dewitt, Williamston, East Lansing, Ann Arbor, and Farmington Hills, is ... for a brain tumor. , Jason Bauer and his family are longtime members ...
(Date:12/7/2016)... ... ... A. Kevin Spann Insurance, a New York-based firm offering insurance and financial consultation ... drive to raise funds that will benefit the Marine Corps League. , The Marine ... Corpsmen. Working closely with the MCL, the A. Kevin Spann team plans to generate ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... Delete® - ... in Time For The Holiday Party Season. Save Up To 33% Off Botox® and ... Salon is providing the Phoenix Valley with Delightful Deals on Botox® and ...
(Date:12/7/2016)... ... 2016 , ... Gensuite is honored to be selected as ... Product Launch category. Gensuite’s entry on their EZ Scan feature detailed the tool’s ... Training Group is a professional event and training provider based in the United ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7, 2016  Organovo Holdings, Inc. (NASDAQ: ... focused on delivering scientific and medical breakthroughs using ... and Chief Executive Officer Keith Murphy ... December 14, 2016 at 1:00 p.m. Eastern Time ... yet familiar with the Company, an informational video ...
(Date:12/7/2016)... Today, Stock-Callers.com presents four Biotech equities for review, ... Pharmaceuticals Inc. (NASDAQ: ANTH ), ProNAi Therapeutics Inc. ... AVXS ). From its peak in July 2015, the ... level equal to what it saw at the start of ... year, it has still out-performed other market sectors, beating the ...
(Date:12/7/2016)... 7, 2016  Lannett Company, Inc. (NYSE: LCI ) ... Markets 2016 Prescription for Success Healthcare Conference on December 14, 2016 ... New York City . In addition, the ... Guggenheim Securities 4 th Annual Boston Healthcare Conference taking place ... ...
Breaking Medicine Technology: