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Marilyn B. Gula Mountains of Hope Foundation grants $100,000 to TGen
Date:11/15/2012

PHOENIX, Ariz. A gourmet culinary fte has raised $100,000 for groundbreaking breast cancer research at the non-profit Translational Genomics Research Institute (TGen).

The Marilyn B. Gula Mountains of Hope Foundation raised the $100,000 through its 2nd annual "Cookin' for a Cure at Eddie's House," a fundraising event in March at award-winning chef Eddie Matney's exclusive Scottsdale restaurant.

Mountains of Hope has donated the funds to a research project led by Dr. Heather Cunliffe, head of TGen's Breast and Ovarian Cancer Research Unit. The research will focus on a specific and difficult-to-treat type of cancer called primary Luminal B breast cancer one of at least five major subtypes of breast cancer.

"We feel confident that this project will enable Dr. Cunliffe and her team to determine the genetic variables that are driving this particular type of breast cancer," said Phoenix businessman Allen Gula Jr., Chairman of the Mountains of Hope Foundation, whose late wife Marilyn died of breast cancer in 2006 following a decade-long battle against the disease. "This research is especially important to patients with advanced breast cancer, who have fewer treatment options."

TGen's goal is to learn enough about the possible genomic causes of Luminal B breast cancer to initiate a clinical trial within 3-5 years. Luminal B tumors account for approximately 19 percent of the nearly 227,000 new cases of invasive breast cancer each year in the U.S.

"We are entering a new era of evidence-based precision therapeutics for individual patients," Dr. Cunliffe said. "The goal of a clinical trial based on this study would be to prevent disease recurrence in patients with early stage Luminal B breast cancer through the use of targeted treatments."

A major problem with this type of cancer is the tumor's resistance to conventional chemotherapy. While Luminal B tumors are fueled by estrogen, they are often not responsive to anti
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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

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