Navigation Links
Mapping gene expression with Gene Expression Atlas
Date:6/15/2009

Hinxton, 15 June 2009 Today, researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.

Although most cells in an organism share the same genetic information, different cell types, for example skin and liver cells, have different properties and functions, largely because different genes are active in these cells. The Gene Expression Atlas is a new database that allows users to query gene expression under a range of biological conditions, including different cell types, developmental stages, physiological states, phenotypes and disease states. The key questions this new database can answer can be summarised as:

  1. under which conditions is my particular gene of interest expressed?
  2. which genes are expressed in a particular condition? For example, what genes are specifically active in kidney cells, or how does the expression of genes in leukemic blood differ compared to normal blood?

Both questions can also be combined to focus on particular genes and their role in a specific disease, such as identifying members of the Wnt signalling pathway that are expressed in cancer.

The Atlas collates data from over 1000 different independent studies, mainly microarray experiments, with more than 30,000 samples in total. The new database is the latest product of the EBI's Microarray Informatics group and has its origins in the EBI's ArrayExpress resource. After a phase of development, the Atlas is ready to begin its own life as an independent major resource. Misha Kapushesky, Atlas project leader at the EBI commented, "While the ArrayExpress Archive makes data from high throughput functional genomics assays available to experts, Gene Expression Atlas presents this information in a format accessible to any biologist. The Atlas takes data directly from the ArrayExpress Archive, which is then enriched by curation, re-annotation and statistical computations before the results are presented to the user in an easily accessible form."


'/>"/>

Contact: Katrina Pavelin
contactpress@ebi.ac.uk
44-122-349-4452
European Molecular Biology Laboratory
Source:Eurekalert

Related medicine news :

1. Language centers revealed, brain surgery refined with new mapping
2. Mapping tool allows emergency management personnel to visually track resources
3. Mapping of prostate cancer genes opens the door to new treatments
4. Texas Cardiac Arrhythmia Institute at St. Davids Medical Center First in the Nation to Use a New Generation of Medical Robots for Complex Electrophysiology Mapping Procedures
5. First-Ever Mapping of Cancer Patients Genome
6. Deep brain mapping to isolate evidence of Gulf War syndrome
7. Global Mapping Tool Demonstrates Medical Donation Impact
8. UH research team developing new noninvasive brain-mapping technology
9. Elsevier and Brain Mapping Foundation co-host 6th Annual World Congress of IBMISPS
10. Elekta Chosen to Deliver Sophisticated Brain Mapping Technology to the Mind Research Network
11. Altered expression of ultraconserved noncoding RNAs linked to human leukemias and carcinomas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... April 29, 2016 , ... ... Footwear Foundation, the national charitable foundation serving the footwear industry, has broken all ... representing more than 130 companies across 23 states during the months of April ...
(Date:4/29/2016)... ... April 29, 2016 , ... Our bodies are bombarded daily by environmental ... deal with these stressors is to adopt a more healthful diet, but too many ... Groux, a certified Holistic Nutritionist and the creator of the Newport Beach Cleanse and ...
(Date:4/29/2016)... ... April 29, 2016 , ... Dr. Bernie ... best seller "LOVE, MEDICINE and MIRACLES") addresses touchy topics related to Death live ... thereafter . Dr. Bernie Siegel, author of a plethora of essential books-to-read ...
(Date:4/29/2016)... ... April 29, 2016 , ... Coast Dental Fort Stewart is ... its new location in the Exchange Furniture Mall at 112 Vilseck Road in Fort ... Samsung Smart TV. Plus attendees will have the opportunity to meet general dentists Thomas ...
(Date:4/29/2016)... , ... April 29, 2016 , ... ... that student team BioCellection won the $30,000 Perlman Grand Prize of the 2016 ... Gloeckner Undergraduate Award, the Michelson People’s Choice Award, and the Committee Award for ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... NEW YORK , April 28, 2016 ... of online consumer insights on healthcare, announced today that ... in their report Cool Vendor in Life Sciences, ... , April 15, 2016.  The report focuses on life-science- ... to gain insight from patients and doctors, confirm medication ...
(Date:4/28/2016)... Dr. Vivek Ahuja , ... phen Schmidt Join the Growing ... solutions for life sciences, today announced key new leaders have joined ... to a growing business.  This will bolster the company,s safety business ... joined ArisGlobal in the position of Vice President - Safety. George ...
(Date:4/28/2016)...   Acsis , a leading provider of supply ... research and advisory firm IDC has named it a ... Pharmaceutical Track and Trace Software 2016 Vendor Assessment (doc ... of the capabilities and business strategies of 10 vendors ... Logo - http://photos.prnewswire.com/prnh/20160427/360791LOGO ...
Breaking Medicine Technology: