Navigation Links
Mapping gene expression with Gene Expression Atlas
Date:6/15/2009

Hinxton, 15 June 2009 Today, researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.

Although most cells in an organism share the same genetic information, different cell types, for example skin and liver cells, have different properties and functions, largely because different genes are active in these cells. The Gene Expression Atlas is a new database that allows users to query gene expression under a range of biological conditions, including different cell types, developmental stages, physiological states, phenotypes and disease states. The key questions this new database can answer can be summarised as:

  1. under which conditions is my particular gene of interest expressed?
  2. which genes are expressed in a particular condition? For example, what genes are specifically active in kidney cells, or how does the expression of genes in leukemic blood differ compared to normal blood?

Both questions can also be combined to focus on particular genes and their role in a specific disease, such as identifying members of the Wnt signalling pathway that are expressed in cancer.

The Atlas collates data from over 1000 different independent studies, mainly microarray experiments, with more than 30,000 samples in total. The new database is the latest product of the EBI's Microarray Informatics group and has its origins in the EBI's ArrayExpress resource. After a phase of development, the Atlas is ready to begin its own life as an independent major resource. Misha Kapushesky, Atlas project leader at the EBI commented, "While the ArrayExpress Archive makes data from high throughput functional genomics assays available to experts, Gene Expression Atlas presents this information in a format accessible to any biologist. The Atlas takes data directly from the ArrayExpress Archive, which is then enriched by curation, re-annotation and statistical computations before the results are presented to the user in an easily accessible form."


'/>"/>

Contact: Katrina Pavelin
contactpress@ebi.ac.uk
44-122-349-4452
European Molecular Biology Laboratory
Source:Eurekalert

Related medicine news :

1. Language centers revealed, brain surgery refined with new mapping
2. Mapping tool allows emergency management personnel to visually track resources
3. Mapping of prostate cancer genes opens the door to new treatments
4. Texas Cardiac Arrhythmia Institute at St. Davids Medical Center First in the Nation to Use a New Generation of Medical Robots for Complex Electrophysiology Mapping Procedures
5. First-Ever Mapping of Cancer Patients Genome
6. Deep brain mapping to isolate evidence of Gulf War syndrome
7. Global Mapping Tool Demonstrates Medical Donation Impact
8. UH research team developing new noninvasive brain-mapping technology
9. Elsevier and Brain Mapping Foundation co-host 6th Annual World Congress of IBMISPS
10. Elekta Chosen to Deliver Sophisticated Brain Mapping Technology to the Mind Research Network
11. Altered expression of ultraconserved noncoding RNAs linked to human leukemias and carcinomas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... Cary, North Carolina (PRWEB) , ... June 26, 2016 , ... ... the release of a new product that was developed to enhance the health of ... harvested for centuries. , The two main herbs in the PawPaws Cat Kidney ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... ... 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can ... CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn ... X . Simply select a ProHand generator and drag it above media or text ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)... 23, 2016 Any dentist who has made an ... current process. Many of them do not even offer this ... and high laboratory costs involved. And those who ARE able ... such a high cost that the majority of today,s patients ... Parsa Zadeh , founder of Dental Evolutions Inc. and ...
Breaking Medicine Technology: