Navigation Links
Many stroke, heart attack patients may not benefit from aspirin
Date:2/25/2008

BUFFALO, N.Y. -- Up to 20 percent of patients taking aspirin to lower the risk of suffering a second cerebrovascular event do not have an antiplatelet response from aspirin, the effect thought to produce the protective effect, researchers at the University at Buffalo have shown.

Millions of people use low-dose aspirin either for prevention of a second stroke, second heart attack or second episode of peripheral artery disease, said Francis M. Gengo, Pharm.D., lead researcher on the study.

Gengo is professor of neurology in the UB School of Medicine and Biomedical Sciences and professor of pharmacy practice in the UB School of Pharmacy and Pharmaceutical Sciences.

In those three indications, its crystal clear that aspirin reduces the risk of a second heart attack or stroke in most patients. But we have known for years that in some stroke and heart attack patients, aspirin has no preventive effect.

With no definitive data on the frequency of this condition, known as aspirin resistance, physicians were left with a best guess of between 5 and 50 percent, said Gengo.

UB researchers now have confirmed the 20 percent figure through a strictly controlled study conducted over 29 months in 653 consecutive stroke patients seen at Dent Neurologic Institute offices in the Buffalo suburbs Amherst and Orchard Park.

Results of the study were published Jan. 28 on the Journal of Clinical Pharmacologys website as a document of interest and will appear in a future issue of the journal.

Aspirin lowers the risk of a cardiovascular event by preventing blood platelets from aggregating in the arteries and obstructing blood flow. If blood drawn from a patient taking aspirin shows that platelets are still aggregating, that patient is diagnosed as being aspirin resistant. If a stroke patient has a second stroke while on aspirin, the patient has experienced what is known as clinical aspirin failure.

Weve known
'/>"/>

Contact: Lois Baker
ljbaker@buffalo.edu
716-645-5000 x1417
University at Buffalo
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. REACH Registry Highlights That Patients With Peripheral Arterial Disease (PAD) Suffer High Rates of Heart Attack, Stroke, Hospitalization, and Death
2. The Blessing of a Brain Injury: Author Survives Injury to Brain Following Stroke, Uses Injury as Fuel to Overcome Odds
3. Some types of temporary neurological problems associated with increased risk for stroke, dementia
4. Temporary Amnesia, Confusion Raise Stroke, Dementia Risk
5. Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials
6. Drug for cluster headaches may cause heart problems
7. Use of certain lipid measures not more effective in predicting coronary heart disease
8. Restricting Blood Flow May Help Heart Bypass Patients
9. Urban Smog Tough on Young Adults Hearts
10. Stanford study highlights cost-effective method of lowering heart disease risks
11. Vitamin Es lack of heart benefit linked to dosage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... OR (PRWEB) August 20, 2014 August ... are urged to become educated about eye health and ... examined. One frequently overlooked eye condition that must be ... Sharon Kleyne Hour Power of Water radio show, is ... children increasing exponentially, childhood dry eye is becoming a ...
(Date:8/20/2014)... In a recent article published by ... London (UCL) study showed that dental experts from around ... teeth was the most effective. Analysis of 66 different ... were frequently recommended, but none were favored by a ... experienced cosmetic dentist Dr. Patrick J. Broome, ...
(Date:8/20/2014)... 2014 B. E. Smith, the only ... has been retained to lead a national chief ... System in Hermiston, Ore. The top executive search ... has recently placed more than 900 healthcare executives into ... a progressive, not-for-profit healthcare organization serving a population of ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 Oxnard ... founder of the Anacapa Dental Art Institute, is presenting ... Dr. Jivraj will be speaking on All-on-4 dental ... Aspects of Graft Less Solutions” at 12:40 p.m. Sept. ... in Vancouver, British Columbia, Canada. , “The All-on-4 procedure ...
(Date:8/20/2014)... Washington, DC (PRWEB) August 20, 2014 ... Got Heart, Give Hope® Celebration to be hosted in ... Army and Navy Club. This signature event honors the ... the families of the fallen. Proceeds from the Got ... Warriors®, a national nonprofit dedicated to restoring a sense ...
Breaking Medicine News(10 mins):Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 2Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 3Health News:Ending Confusion About the Best Way to Brush Teeth 2Health News:Ending Confusion About the Best Way to Brush Teeth 3Health News:Good Shepherd Health Care System Retains B. E. Smith to Recruit New COO 2Health News:Good Shepherd Health Care System Retains B. E. Smith to Recruit New COO 3Health News:Internationally Known Oxnard Dentist to Speak at Conference in Vancouver 2Health News:Internationally Known Oxnard Dentist to Speak at Conference in Vancouver 3Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Washington, DC 2
... MENLO PARK, Calif., Oct. 23 SRI International, ... today that Dr. Elizabeth Shriberg, a senior researcher ... has been named a Fellow of the International ... at Interspeech 2009 in Brighton, England, recognizes significant ...
... SILVER SPRING, Md., Oct. 23 The U.S. Food ... a request from the U.S. Centers for Disease Control ... (EUA) for the investigational antiviral drug peramivir intravenous (IV) ... suspected 2009 H1N1 influenza infection who are admitted to ...
... International Dairy Foods Association applauded Agriculture Secretary Tom Vilsack ... offering more low fat milk and dairy products in ... improve the quality of school meals, one of the ... outlined the Obama Administration,s agenda for Child Nutrition Act ...
... Singer/Songwriter Patti Austin Headline Annual Andrus Awards Gala ... leadership in communication , LAS VEGAS, Oct. 24 ... to acclaimed television pioneer Norman Lear at a celebration ... and expo. Lear, creator of shows including " All in the ...
... Surgery 2009 News Briefs are designed to keep you ... at the annual meeting of the American Society of ... briefs are embargoed until the date/time they are presented. ... for media registration, or to arrange interviews with presenters, ...
... that injection sting is excessive disputed in U.S. study , ... that injections of the human papillomavirus (HPV) vaccine are especially ... more than any other shots. , Public health officials worried ... getting the vaccine, which protects against a virus that can ...
Cached Medicine News:Health News:SRI International Researcher Receives International Speech Communication Association (ISCA) Fellow Award 2Health News:SRI International Researcher Receives International Speech Communication Association (ISCA) Fellow Award 3Health News:FDA Authorizes Emergency Use of Intravenous Antiviral Peramivir for 2009 H1N1 Influenza for Certain Patients, Settings 2Health News:IDFA Supports Obama Administration's Commitment to Encourage Schools to Provide More Low Fat Milk and Dairy Products in Schools 2Health News:Legendary TV Producer Norman Lear Receives AARP's Highest Honor 2Health News:Legendary TV Producer Norman Lear Receives AARP's Highest Honor 3Health News:Plastic Surgery 2009 news briefs 2Health News:Plastic Surgery 2009 news briefs 3Health News:Plastic Surgery 2009 news briefs 4Health News:Plastic Surgery 2009 news briefs 5Health News:Plastic Surgery 2009 news briefs 6Health News:HPV Vaccine No More Painful Than Other Shots 2
(Date:8/19/2014)... British Columbia and MENLO PARK, Calif. ... (OTCQB: DMPI) ("DelMar" "the company") announced today a protocol ... trial had been filed with the U.S. Food and Drug ... 50mg/m 2 has been opened at three clinical trial ... company also confirmed that gross proceeds of US$2.9 million have ...
(Date:8/19/2014)... 2014 ,Weight Loss- Market Analysis, ... report provides comprehensive insights about phase III pipeline drugs ... of the report is to establish the understanding for ... across the different countries and regions. While the leading ... also provides details on the drug master filings across ...
(Date:8/18/2014)... Israel , Aug. 19, 2014 Immune ... Stockholm : "IMNP"), a biotechnology company, today announced ... its common stock on the NASDAQ Capital Market has been ... NASDAQ OMX Group. IMMUNE,s common stock is expected to begin ... trading on August 21, 2014 under the symbol IMNP. ...
Breaking Medicine Technology:DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 2DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 3DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 4DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 5DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 6DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 7Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 2Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 3Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 4Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 2Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 3Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 4
... Miami HEAT forward Juwan Howard and Basketball Hall of Famer ... for Adolescent Health and Medicine (SAHM) today to bring ... for Teens is a national awareness campaign designed to ... against serious and potentially life-threatening diseases. To ...
... 2011 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. (Nasdaq: CHBT ... of probiotics products in China, today reported its unaudited financial results ... year ended December 31, 2010. Third ... Net sales increased 39.0% y-o-y to $32.4 million; ...
Cached Medicine Technology:Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 2Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 3Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 4Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 5China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 2China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 3China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 4China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 5China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 6China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 7China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 8China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 9China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 10China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 11
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: