Navigation Links
Many advanced breast cancer patients do not receive recommended treatment
Date:6/26/2011

Radiation after a mastectomy for women with advanced breast cancer saves lives, but almost half of these patients do not receive it. That is the conclusion of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study's results indicate that treatments that have proven their life-saving potential in clinical trials may not be available to many patients.

After clinical trials in the 1990s revealed the benefits of radiation after mastectomy in advanced breast cancer patients, several major treatment guidelines were published that recommended radiation for these women after their surgery. To investigate whether these recommendations are being followed, Shervin Shirvani, MD, and Benjamin Smith, MD, of the MD Anderson Cancer Center in Houston, led a team that analyzed information from 38,322 women aged ≥ 66 years treated with mastectomy for invasive breast cancer between 1992 and 2005. (The researchers obtained data from the Surveillance, Epidemiology, and End Results [SEER]-Medicare database, which links cancer registry data to a master file of Medicare enrollment.)

While radiation use increased from 36.5 percent to 57.7 percent between 1996 and 1998 with the publication of landmark clinical trials, no further increase in use was observed between 1999 and 2005 despite the publication of multiple guidelines endorsing it. During this period, only approximately 55 percent of older high-risk breast cancer patients who should have undergone radiation actually received it. According to Dr. Smith, because the percentage of women treated with radiation did not increase after treatment guidelines were published, it seems that these guidelines were not able to improve the quality of care that breast cancer patients received.

"When physicians are not guided by published evidence, there is the chance that patient outcomes will suffer or that patients will undergo unnecessary treatments and tests," said Dr. Shirvani. "Furthermore, beyond the potential for distress and injury to the individual patient, there is also the strong likelihood that medical resources will be wasted on unproven or ineffective treatments." The findings indicate that greater efforts are needed to ensure that what's learned from clinical trials actually affects care in the community.


'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Black heart attack patients wait longer for advanced treatment, University of Michigan study shows
2. Many patients with advanced cancers get treatments that wont help
3. Two Drugs Shown to Prolong Survival in Advanced Melanoma Cases
4. Antifungal drug delays need for chemo in advanced prostate cancer
5. Penn study identifies genes that may help predict response to BRAF inhibitors for advanced melanoma
6. New Drug Extends Survival for Men With Advanced Prostate Cancer
7. Surgery Viable for Advanced Prostate Cancer, Study Finds
8. Heavy Smoking Tied to Advanced Kidney Cancer
9. Advanced-stage prostate cancer patients experience 20-year survival rates with surgery
10. Advanced CT with 3-D scanning improve detection of drug trafficking and other contraband smuggling
11. Smoking Could Raise Odds for Advanced Kidney Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet’s ... ostomy patients, standing as living proof that attitude and determination can combine into ... issues that spike around the holidays. This campaign will offer patients a new-found ...
(Date:12/2/2016)... ... 02, 2016 , ... Mediaplanet is proud to announce the ... the innovative treatments, therapeutic technologies, and revolutionized nutrition that are helping patients and ... 6 years in the last 3 decades,” says Dr. Valentine Fuster, a world-renowned ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... ... veterinarian diagnostic imaging systems and the first company to offer robotic ... a Heart at their tradeshow booth # 941 for the American Association of ...
(Date:12/2/2016)... Abilene, Texas (PRWEB) , ... December 02, 2016 , ... ... article that delves into how this current generation fits into Bible Prophecy. Yisrayl says ... lists various facts pointing to this conclusion, showing how the details line up exactly ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... meals to needy individuals and families from eight different sites throughout Miami-Dade and ... Day. Over 1,000 volunteers worked very hard on Thanksgiving morning by putting together ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... YORK , December 2, 2016 ... Braces & Support) is Expected to Gain a Significant Market ... to Orthopedic Ailments  ... , According to ... Study on Medical Implants Sterile Packaging: Clamshell Product Type Segment ...
(Date:12/2/2016)... On Thursday, the NASDAQ Composite and ... the Dow Jones Industrial Average managed to stay in green. ... which prompted Stock-callers this morning to look at the performances ... NUVA ), Smith & Nephew PLC (NYSE: SNN ... Cesca Therapeutics Inc. (NASDAQ: KOOL ). You can ...
(Date:12/2/2016)... -- The concept of rare diseases and the idea that ... has been taking shape in Europe ... initiatives related to orphan medicinal products have been emerging at ... states individually. Many member states in the EU have led ... medicinal products, the result of which took the shape of ...
Breaking Medicine Technology: