Navigation Links
Many Heart Defects Aren't Inherited, Study Finds
Date:5/13/2013

SUNDAY, May 12 (HealthDay News) -- At least 10 percent of severe genetic heart defects are caused by new gene mutations that were not passed down from patients' parents, a new study finds.

Congenital heart disease is the most common form of birth defect and occurs in nearly 1 percent of newborns.

"These findings provide new insight into the causes of this common congenital disease," senior study author Richard Lifton, chair of the genetics department at the Yale School of Medicine, said in a university news release.

Lifton's tream analyzed the genes of more than 1,800 people and identified hundreds of mutations that can cause congenital heart disease. In particular, the investigators found that frequent mutations occurred in genes that affect what's known as histones. Histones are proteins that package DNA in the cell's nucleus and control the timing and activation of genes that may be key to fetal development.

The study was published online May 12 in the journal Nature.

"Most interestingly, the set of genes mutated in congenital heart disease unexpectedly overlapped with genes and pathways mutated in autism," Lifton said. "These findings suggest there may be common pathways that underlie a wide range of common congenital diseases."

"This is an important piece of the puzzle that gives us a clearer picture of the causes of congenital heart disease," Dr. Gary Gibbons, director of the U.S. National Heart, Lung, and Blood Institute, added in the news release. The institute funded the study.

More information

The March of Dimes has more about congenital heart defects.

-- Robert Preidt

SOURCE: Yale University, news release, May 12, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Mount Sinai Researchers Identify Gene Mutations in Congenital Heart Disease
2. Researchers take important step in unlocking what causes congenital heart disease
3. Pets a Boon for the Human Heart, Cardiologists Say
4. iPads Could Affect Implanted Heart Devices, Early Study Finds
5. Everyday Noise Levels May Affect the Heart
6. Swimming Pools May Pose Hazard for People With Heart Devices
7. Fish Oil Supplements Dont Protect Against Heart Trouble: Study
8. WomenHeart Wins “Full Circle Award” at the 4th M2W®-HW™ - The Marketing Health & Wellness to Women Conference
9. Docs Should Ask Heart Patients About Quality of Life
10. Heart Attack Preventing Drug, Plavix, Poses Continued Risk While Bristol-Myers Squibb Extends the Rights to Others for Generic OTC Versions
11. Duke scientists build a living patch for damaged hearts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Many Heart Defects Aren't Inherited, Study Finds
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... Ducks Publishing announces the winning of the Mom,s Choice Award for ... The award-winning book, a remarkably frank account of prostate cancer survival, ... , ... South Bend, IN (PRWEB) March 19, 2009 ...
... March 19 The "2009 European Mammography ... to FUJIFILM Corporation in recognition of the ... mammography systems. The company,s superior quality control, ... manufacturing are also commended.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ...
... designed to extend audit reach for customers that need ... SAFC(R), a member of the Sigma-Aldrich Group (Nasdaq: ... new Vendor Audit Services aimed at customers ... raw materials and key intermediates destined for their manufacturing ...
... For women with recurrent breast cancer, the treatment the ... original breast cancer. A group from Toronto has recently completed ... with a biopsy of suspected tumors that recurred elsewhere in ... 20% of the women having a significant change in their ...
... Injury Awareness MonthWHEATON, Ill., March 18 Sports and recreation ... in the U.S. each year according to the Centers for ... traumatic brain injury (TBI) caused by a blow or jolt ... It is important to note that even if you do ...
... Keystone Symposia on Molecular and Cellular Biology will ... in 1984 when it convenes its scientific conferences on ... From Infection to Immune Control " at Keystone Resort ... from around the world will attend.These joint conferences will ...
Cached Medicine News:Health News:Cancer Book Honored With Prestigious Mom's Choice Award 2Health News:Frost & Sullivan Recognises FUJIFILM Corporation's Outstanding Product Quality Leadership 2Health News:Frost & Sullivan Recognises FUJIFILM Corporation's Outstanding Product Quality Leadership 3Health News:Frost & Sullivan Recognises FUJIFILM Corporation's Outstanding Product Quality Leadership 4Health News:SAFC(R) Underlines Commitment to Pharmaceutical Supply Chain Quality With New Global Vendor Audit Services 2Health News:SAFC(R) Underlines Commitment to Pharmaceutical Supply Chain Quality With New Global Vendor Audit Services 3Health News:SAFC(R) Underlines Commitment to Pharmaceutical Supply Chain Quality With New Global Vendor Audit Services 4Health News:Research shows biopsy of recurrent breast cancer can alter treatment 2Health News:Sports Concussions: Common and Preventable 2Health News:Keystone Symposia to Mark 25th Anniversary of its First HIV/AIDS Meeting 2Health News:Keystone Symposia to Mark 25th Anniversary of its First HIV/AIDS Meeting 3
(Date:12/22/2014)... CHESTERBROOK, Pa. and STOCKHOLM ... AB (publ) (Sobi) and partner Auxilium Pharmaceuticals, Inc. today ... Use (CHMP) of the European Medicines Agency (EMA) has ... (collagenase clostridium histolyticum) for the treatment of adult men ... deformity of at least 30 degrees at the start ...
(Date:12/22/2014)... Maine , Dec. 22, 2014  Mark ... analysis brief providing a summary of the 2015 ... plan enrollment trends.  According to ... for Planning and Evaluation, Department of Health and ... were enrolled in individual medical plans through the ...
(Date:12/22/2014)... , Dec. 22, 2014  Pfenex Inc. (NYSE ... recombinant anthrax vaccine, has been filed and is now ... provided by the Department of Health and Human Services ... (BARDA). "We are extremely pleased to have ... Px563L.  This represents a significant milestone in our company,s ...
Breaking Medicine Technology:Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6Insights into the Marketplace and Individual Market Growth 2Pfenex Announces Active IND and Additional BARDA Funding for Recombinant Anthrax Vaccine Program, Px563L 2Pfenex Announces Active IND and Additional BARDA Funding for Recombinant Anthrax Vaccine Program, Px563L 3
... Ikaria Holdings, Inc. today announced that it has been ... by the New Jersey Business & Industry Association (NJBIA), ... Ikaria earned the award based on criteria including ... creation of new jobs. , "We are delighted that ...
... 21 PharmaNet Development Group, Inc., a leading provider ... and medical device companies, today announced its participation at ... place at the World Trade Center in Rotterdam, The ... the conference, top management will discuss some of the ...
Cached Medicine Technology:Ikaria Receives Award for Excellence by New Jersey Business & Industry Association 2PharmaNet Development Group Management Participates in the 8th Annual Partnerships in Clinical Trials Conference in Rotterdam 2
... Stains for Geometric Data Hemastainer. ... Stains are quality control tested ... ensure proper staining and absence ... applications for a minimum of ...
... for Geometric Data Hemastainer. Formulated ... are quality control tested on ... proper staining and absence of ... for a minimum of eight ...
Wright-Giemsa Stain Solutions...
... used for staining of peripheral blood ... oldest stain formulations still in use ... that of Giemsa stain, although eosinophillic ... basophilic granules and nuclear chromatin stain ...
Medicine Products: