Navigation Links
Many Heart Defects Aren't Inherited, Study Finds
Date:5/13/2013

SUNDAY, May 12 (HealthDay News) -- At least 10 percent of severe genetic heart defects are caused by new gene mutations that were not passed down from patients' parents, a new study finds.

Congenital heart disease is the most common form of birth defect and occurs in nearly 1 percent of newborns.

"These findings provide new insight into the causes of this common congenital disease," senior study author Richard Lifton, chair of the genetics department at the Yale School of Medicine, said in a university news release.

Lifton's tream analyzed the genes of more than 1,800 people and identified hundreds of mutations that can cause congenital heart disease. In particular, the investigators found that frequent mutations occurred in genes that affect what's known as histones. Histones are proteins that package DNA in the cell's nucleus and control the timing and activation of genes that may be key to fetal development.

The study was published online May 12 in the journal Nature.

"Most interestingly, the set of genes mutated in congenital heart disease unexpectedly overlapped with genes and pathways mutated in autism," Lifton said. "These findings suggest there may be common pathways that underlie a wide range of common congenital diseases."

"This is an important piece of the puzzle that gives us a clearer picture of the causes of congenital heart disease," Dr. Gary Gibbons, director of the U.S. National Heart, Lung, and Blood Institute, added in the news release. The institute funded the study.

More information

The March of Dimes has more about congenital heart defects.

-- Robert Preidt

SOURCE: Yale University, news release, May 12, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Mount Sinai Researchers Identify Gene Mutations in Congenital Heart Disease
2. Researchers take important step in unlocking what causes congenital heart disease
3. Pets a Boon for the Human Heart, Cardiologists Say
4. iPads Could Affect Implanted Heart Devices, Early Study Finds
5. Everyday Noise Levels May Affect the Heart
6. Swimming Pools May Pose Hazard for People With Heart Devices
7. Fish Oil Supplements Dont Protect Against Heart Trouble: Study
8. WomenHeart Wins “Full Circle Award” at the 4th M2W®-HW™ - The Marketing Health & Wellness to Women Conference
9. Docs Should Ask Heart Patients About Quality of Life
10. Heart Attack Preventing Drug, Plavix, Poses Continued Risk While Bristol-Myers Squibb Extends the Rights to Others for Generic OTC Versions
11. Duke scientists build a living patch for damaged hearts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Many Heart Defects Aren't Inherited, Study Finds
(Date:9/16/2014)... 2014 Keep that sexy decolletage as you ... neck. , "The Face Whisperer Neck & Decollete Cream ... Heshelow, founder of Sublime Beauty®. "It contains rich ingredients to ... and arnica." , A special ingredient is Argireline, known as ... rich anti-aging cream comes in an airless pump bottle, and ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 Today, ... published new information on transitioning employees to individual ... with the Affordable Care Act (ACA) in full ... be steering some or all of their employees ... surprise. With guaranteed issue plans, coverage for pre-existing ...
(Date:9/16/2014)... the well-known wedding dress manufacturer and retailer, has unveiled ... Additionally, the firm has launched a promotion for its ... up to 62 percent off. , All ... won a lot of positive reviews for its high-quality ... big savings on many other items, including corset bridesmaid ...
(Date:9/16/2014)... 16th, 2014; San Francisco) In a healthcare ... weighed against potential benefit, a Yale study has ... less-aggressive radiation procedures on elderly women with early-stage ... presented at the 56th annual conference of the ... (Abstract 131: Evaluating National Practice in Radiotherapy for ...
(Date:9/16/2014)... Recently, iFitDress.com, one of the most famous dress suppliers ... evening gown collection. According to the company’s sales manager, ... (up to 69% off) at present. Additionally, all the company’s ... am a frequent caller of your site. I like your ... feel quite happy. All items are of good quality. I ...
Breaking Medicine News(10 mins):Health News:15% Off Face Whisperer® Neck & Decollete Cream Now from Sublime Beauty; Care For This Delicate Skin That Shows Age Quickly 2Health News:Zane Benefits Publishes New Information on Transitioning Employees to Individual Health Insurance 2Health News:New Elegant Evening Wear Assortment Released By UWDress.com 2Health News:iFitDress.com: One Shoulder Evening Gown Collection Unveiled Online 2
... a 60-cm-long sword that had been thrust through the nose ... ear, news reports said Wednesday. ,Ronnachai Tiemsanguan, 16, ... sword's removal from his face in an operation that took ... newspaper. ,Ronnachai received his sword wound Saturday when ...
... in the field of conducting tasks that involve spatial ... light turns green. , Researcher Eric Schumacher, ... Technology and colleagues, were surprised when they conducted MRI ... ,The researchers were testing the notion that areas ...
... suggests that ovarian cancer cells form by hijacking a ... Scientists at the Georgia Institute of Technology and the ... involved in the development of fallopian tubes and is ... ovarian tissue. The discovery not only provides a new ...
... Barbara, California – March 6, 2007 -- A team ... Berkeley and StrataGent// Life Sciences, of Los Gatos, California, ... to deliver protein drugs into the skin without the ... The research was published online today in the Proceedings ...
... It's already been established that type 2 diabetes increases the ... also a link between type 1 diabetes and this type ... but still, those with type 1 diabetes have a likelihood ... in non-diabetics. This is similar to the risk those with ...
... International Narcotics Control Board (INCB) – an independent body ... control// standards – is calling for the danger of ... ,In its annual report, the Vienna-based organisation ... drugs are not illegally manufactured or diverted from authorised ...
Cached Medicine News:Health News:Same Areas of the Brain Prepare for and Respond to a Stimulus, Say Experts 2Health News:Ovarian Cancer May Mimic Fallopian Tube Formation 2Health News:Ovarian Cancer May Mimic Fallopian Tube Formation 3Health News:Researchers Design Pulsed Mircrojet System to Deliver Protein Drugs Without Pain or Bruising 2Health News:Flood of Fake Drugs Must Be Stopped, Warns UN 2
(Date:9/16/2014)... 16, 2014 Astellas announced today it ... Communications & Advocacy, Urology in the Americas. Noland will ... Advocacy Margaret Long. In this role, Noland will be ... patient and advocacy organizations, as well as collaborating ... initiatives. Noland,s appointment is the latest phase in ...
(Date:9/16/2014)... 2014 /PRNewswire-iReach/ -- Dan York has been ... of the RTD ® Advanced Wound Care Dressing, ... sales presence in the U.S. Under York,s leadership, GWM ... field sales representatives in new sales territories that will ... add up to 20 sales representatives in major metropolitan ...
(Date:9/16/2014)... DIEGO , Sept. 16, 2014  Denovo ... enzastaurin, a late-stage oncology drug, from Eli Lilly ... to develop, manufacture and commercialize enzastaurin globally, including ... data, and information. Lilly developed ... Phase 2 and Phase 3 clinical trials for ...
Breaking Medicine Technology:Christy Noland to Lead Urology Advocacy and Communications for Astellas 2GWM Products, LLC, announces U.S. market expansion. Dan York added as Director of Sales as part of nationwide growth initiative. 2Denovo Biopharma Acquires Late-Stage Oncology Drug From lilly For Development As A Personalized Medicine 2
... 2011 Reportlinker.com announces that a new market research ... Gastric Cancer Drug Discoveries: what the future holds ... Original analysis of the clinical potential ... candidates put into current market context Original ...
... 2011 Reportlinker.com announces that a new market research report ... Stent Market Outlook to 2016 http://www.reportlinker.com/p0483600/The-Drug-Eluting-Stent-Market-Outlook-to-2016.html ... DES market has seen tremendous growth since the introduction of ... on the release of clinical data that indicated a link ...
Cached Medicine Technology:Reportlinker Adds Gastric Cancer Drug Discoveries: what the future holds 2Reportlinker Adds Gastric Cancer Drug Discoveries: what the future holds 3Reportlinker Adds Gastric Cancer Drug Discoveries: what the future holds 4Reportlinker Adds Gastric Cancer Drug Discoveries: what the future holds 5Reportlinker Adds the Drug-Eluting Stent Market Outlook to 2016 2Reportlinker Adds the Drug-Eluting Stent Market Outlook to 2016 3Reportlinker Adds the Drug-Eluting Stent Market Outlook to 2016 4
... The RapidPCP test is an immunochromatography ... It is,designed for qualitative determination of ... cut-off level of 25 ng/mL. This ... the point of care location,and is ...
... Rapid Opiate II Rapid Opiates is an ... is designed for qualitative determination of Opiates ... presence of morphine in human urine above ... This assay has not been evaluated in ...
... All of DOA Panel ... one step in vitro test. ... of drug substances in human ... not,been evaluated in the point ...
... an immunochromatography based one step in vitro ... THC and its metabolites in human urine,specimens. ... urine above a cut-off,level of 50 ng/mL ... been evaluated in the point of care,location ...
Medicine Products: