Navigation Links
Many HIV Patients Carry Strain With Drug-Resistant Mutation
Date:2/28/2011

MONDAY, Feb. 28 (HealthDay News) -- A new study estimates that between 10 percent and 15 percent of HIV patients in Europe and the United States are infected with a form of HIV that already has at least one drug-resistant mutation.

The researchers found that the risk of treatment failure in these patients is three times higher than normal, and said their findings confirm the need for drug resistance testing in new patients to determine which antiretroviral drugs are most likely to be successful.

For the study, 10,056 HIV patients who were beginning combination antiretroviral therapy (cART) for the first time were categorized into three resistance categories: 90.5 percent (9,102 patients) had no transmitted drug-resistance (TDR); 4.7 percent (475 patients) had at least one mutation and were receiving fully active cART; 4.8 percent (479 patients) had at least one mutation and were resistant to at least one prescribed drug.

Compared to patients without TDR, those with TDR and resistance to at least one prescribed drug were more than three times as likely to experience treatment failure, confirming "the need for at least three fully active antiretroviral drugs to optimize the virological response to a first-line regimen," the researchers wrote.

But the risk of treatment failure was not significantly different between patients without TDR and those with TDR taking a fully active cART regimen containing drugs not compromised by resistance.

The researchers also found that treatment failure was higher among patients with TDR who were taking two nucleotide reverse transcriptase inhibitors (NRTIs) plus one non-nucleotide reverse transcriptase inhibitor (NNRTI) and were predicted to be on a fully active treatment, compared to patients on protease inhibitor-based regimens whose risk of treatment failure was similar to patients with no TDR.

"If drug-resistant mutations are detected before treatment initiation, a rit
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Doctors Can Influence Patients to Lose Weight: Studies
2. Heart Patients With Depression Often Find ER Delays
3. Experts call for greater pain assessment in hospitals as 65 percent of patients report problems
4. Fish Oil Seems to Help Cancer Patients Preserve Muscle
5. Standard Exams Might Not Catch Full Potential of Brain Damaged Patients
6. New way to identify patients at risk of dysphagia after head and neck cancer treatment
7. Type 1 Diabetes Patients Need New Kidney Therapies: Study
8. Many Dialysis Patients at Risk for High Radiation Exposure
9. Statins Might Help HIV Patients, Study Suggests
10. Most locked-in syndrome patients say they are happy
11. Lack of health insurance limits hepatitis C patients access to latest antiviral therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Many HIV Patients Carry Strain With Drug-Resistant Mutation
(Date:7/13/2014)... HealthDay Reporter FRIDAY, July ... sensor for people with diabetes is being developed to measure ... researchers report. Scientists at Brown University in Providence, R.I., ... It uses light, metal and a special enzyme that changes ... diabetics have to prick their fingers to draw blood to ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Recently, ... retailer, has unveiled its new range of gorgeous ... current market, the demand for elegant Quinceanera outfits ... more beautiful items. All the company’s newly released ... trends. They are all elegant and vivid. ...
(Date:7/13/2014)... Texas (PRWEB) July 13, 2014 Epidemiologists ... aGVHD in the 6MM, from 8,062 diagnosed incident cases ... at an Annual Growth Rate (AGR) of 4.35%, during ... the highest number of diagnosed incident cases of aGVHD ... Spain will have the lowest number of diagnosed incident ...
(Date:7/13/2014)... 2014 Wright & Schulte LLC has ... scheduled in July of 2015, in U.S. District Court, ... in the discovery process in the South Carolina ... presiding over the multidistrict litigation (MDL). The complaints pending ... individuals who allege that they took the statin medication ...
(Date:7/13/2014)... Hope Palliative & Hospice Care announced today that they will ... Senior Living Community in Palatine, IL. The group, called “New ... Wednesdays of every month. This group will begin on ... 55 S. Greeley St. Palatine, IL 60067. It is ... for the group. , “A grief support group is ...
Breaking Medicine News(10 mins):Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 2Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 3Health News:2014QuinceaneraDresses.com Releases Its New Quinceanera Dresses 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 3Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 4Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 2Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 3Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 4Health News:Hope Hospice Announces Grief Support Group at the Tamarack Senior Living Community 2
... cholesterol higher than national guidelines recommend that, if managed, ... a study published in the issue of Neurology, the ... ,The study of 1,040 people hospitalized for ... percent had cholesterol higher than recommended by national guidelines. ...
... the risk of becoming infected with tuberculosis (TB) and ... according to an analysis of previously published in issue ... the world’s population is infected with the bacteria that ... inactive by the immune system, according to background information ...
... Phase 3 study of the drug Vandetanib, marketed by London ... study will cover 508 patients of lung cancer in whom ... countries and 20 sites. , The patients who ... non-small cell lung cancer will be given the once-daily drug ...
... Ruby has been diagnosed with a brain tumor which is at ... led her parents// to approach the doctor who after routine tests ... The doctors have given her three to six months of life ... week course of radiation which is expected to reduce the size ...
... be able to provide ‘safe prawns’ for seafood allergy ... these prawns without the fear of an adverse reaction. ... removing from prawns the proteins that cause an allergic ... in Chemistry & Industry, the magazine of the SCI. ...
... infections such as pneumonia and acute bronchitis, says a ... of hospitalisation. ,Rhinoviruses are among the ... least 50 percent of all common colds. ... illnesses in children is increasingly accepted and has been ...
Cached Medicine News:Health News:Cholesterol in Stroke Patients Exceeds National Guidelines 2Health News:Susceptibility to TB is High Among the Smokers 2Health News:Common Cold may Cause Severe Respiratory Infection 2
(Date:7/10/2014)... July 10, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... it has completed the sale to Galderma of all ... or held by Valeant for $1.4 billion in cash, ... which recently completed its acquisition of Galderma. ... our products to a company that is firmly committed ...
(Date:7/10/2014)... , July 10, 2014 Decision Resources Group ... of the U.S. Food and Drug Administration,s (FDA) approval ... binder Velphoro, which was approved by the FDA in ... kidney disease (CKD) patients on dialysis. Other ... Nephrology (US) Q2 2014 : ...
(Date:1/15/2014)... Mich. , Jan. 15, 2014 As health officials ... flu virus, select Meijer pharmacies in Michigan ... throat to eligible patients, enabling Meijer pharmacists to administer tests ... protocol set by a physician participating in the study. ...
Breaking Medicine Technology:Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3
... With the ProtecPoint Exit Alerting System, ... staff) and assets (e.g. medical equipment), ... your facility. With this form of ... cost savings, operating efficiencies, and overall ...
... Context-sensitive medicine is the ability of medical ... pre-determined ways based on what is happening ... associations a Radianse indoor positioning solution (IPS) ... it requires identity, location and time to ...
... the movement of controlled substances, critical ... done. VerdaSee's "intellishelvess" are designed to ... is possible with no human intervention. ... this possible. VerdaSee Intellishelf™ product solutions ...
Agility has delivered a RFID-enabled mobile asset management program....
Medicine Products: