Navigation Links
Many Cocaine Deaths Determined by Genes, Study Says
Date:1/30/2013

WEDNESDAY, Jan. 30 (HealthDay News) -- People with common mutations on two genes have a nearly eightfold increased risk of dying from cocaine abuse, according to a new study.

The mutations affect how dopamine affects brain activity. Dopamine is a chemical messenger that's vital to the function of the central nervous system. Cocaine is known to block transporters in the brain from absorbing dopamine, the Ohio State University researchers said.

The findings, published online in the January issue of the journal Translational Psychiatry, apply primarily to white people. The study authors found that about one in three whites who died of cocaine abuse had these gene mutations.

A different combination of gene mutations affects the risk of cocaine-abuse death in black people, the researchers said in a university news release.

The mutations associated with the increased risk of cocaine-abuse death in whites were found on genes that are also targeted by drugs to treat some psychiatric disorders.

These findings could help determine how patients with dopamine-related conditions, which include attention-deficit/hyperactivity disorder, bipolar disorder, anxiety and schizophrenia, will respond to certain medications based on whether they have the mutations, the researchers said.

More information

The U.S. National Institute on Drug Abuse has more about cocaine.

--Robert Preidt

SOURCE: Ohio State University, news release, Jan. 22, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
2. Chronic cocaine use triggers changes in brains neuron structure
3. Anti-cocaine vaccine described in Human Gene Therapy Journal
4. Neurons that control overeating also drive appetite for cocaine
5. Synthetic stimulants called bath salts act in the brain like cocaine
6. Illegal Bath Salts Mimic Cocaine in the Brain: Study
7. Cocaine Raises Heart Risks for Fit, Young Adults: Study
8. Treating cocaine dependence: A promising new pharmacotherapy
9. People with low risk for cocaine dependence have differently shaped brain to those with addiction
10. Higher-spending hospitals have fewer deaths for emergency patients
11. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Many Cocaine Deaths Determined by Genes, Study Says
(Date:5/26/2017)... ... May 26, 2017 , ... ... year’s recipient of proceeds from its 14th Annual Clays for Kids fundraiser, to ... Road 30, Bennett, Colorado. , As part of BluSky’s partnership with The ...
(Date:5/26/2017)... ... ... Jack: Against All Odds”: the story of Coach Cactus Jack and the impact he ... creation of published author, Walter Hubbard, a retired wildlife and fisheries biologist and pharmacy ... Walter and Jane have three adult children and a granddaughter. Walter and ...
(Date:5/24/2017)... ... May 24, 2017 , ... Last month, representatives from ... employees, and town officials to celebrate the grand opening of the 87,000 square ... as part of its ongoing relationship with RWJBarnabas Health, New Jersey’s largest health ...
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. Alan I. Benvenisty, MD is dual board ... He is known for his distinguished expertise and experience in the diagnosis and treatment ... training in treating renovascular disease and aortic aneurysm . He is known for ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... management and interpretation, has received U.S. Food and Drug Administration (FDA) 510(k) ... web-based, scalable and secure cloud platform for medical image management. At the core ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... May 10, 2017 Global Health Intelligence ... Latin America , published its 2017 ranking of the ... based on extensive data analysis from GHI,s hospitals database ... database for the region. The GHI database covers 86% of ... more than 130 data points for each institution in key ...
(Date:5/9/2017)... 9, 2017 Zimmer Biomet Holdings, Inc. (NYSE ... today announced it has earned a spot on ... The Company was ranked among 500 U.S. employers as ... Healthcare Equipment and Services. The annual ... anonymous, independent survey of over 30,000 employees across 25 ...
(Date:5/8/2017)... YORK , May 8, 2017 ... the transition from fee for service reimbursement. Black Book ... 2017. 1.       The Market for MIPS ... 77% of physician practices with 3 or more ... Technology Solutions by Q4. "Given the magnitude of the ...
Breaking Medicine Technology: