Navigation Links
Manipulating the immune system like a parasite
Date:4/9/2008

One day it may be possible to mimic the tactics used by parasites to trick the body into accepting transplanted tissues or organs.

That is the hope of Dr Shane Grey from the Garvan Institute for Medical Research and Professor John Dalton from the Institute for the Biotechnology of Infectious Diseases at the University of Technology (UTS). The pair has been awarded a $400,000 grant through the Australian Islet Transplantation Program, administered jointly by the Juvenile Diabetes Research Foundation (JDRF) and the Commonwealth Department of Health and Ageing.

The grant will be divided equally between Garvan and UTS over a period of two years, and will combine Professor Daltons expertise in parasitology and biochemistry with Dr Greys expertise as a transplant immunologist.

When parasites invade humans, they secrete compounds that appear to change the way the immune system sees them. In other words, they alter the immune response.

Over time our immune system has evolved different ways to deal with different organisms and challenges, explained Dr Grey. What the parasite does is deviate the immune system from an effective response to one thats more suited to attacking other organisms or pathogens. Its quite cunning.

By effectively disarming its host, the parasite is doing the equivalent of replacing the weaponry of a modern army with bows and arrows.

The Australian Islet Transplantation Program funds much innovative transplant therapy work in the hope of one day finding a way for recipients to tolerate islet (insulin producing cells in the pancreas) transplants without having to take highly toxic immunosuppressive drugs for the rest of their lives. Many people believe that effective islet transplantation offers the greatest hope for curing Type 1 diabetes, or insulin dependent diabetes.

Before applying for the grant, the Garvan and UTS teams undertook a short pilot study to test their approach. The init
'/>"/>

Contact: Alison Heather
a.heather@garvan.org.au
61-292-958-128
Research Australia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. Immune deficiency linked to a type of eye cancer
3. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
4. Melanoma drug revs immune cells but cancer cells ignore it
5. Study identifies key player in the bodys immune response to chronic stress
6. MedImmune Resolves FDA Observations Regarding Manufacturing Process for FluMist(R)
7. UVA researchers find important clue to immune infertility
8. M.D. Anderson-led team reports possible key to autoimmune disease
9. Their immune cells, fighting your cancer
10. MedImmune Licenses Reverse Genetics Technology to GlaxoSmithKline for Use in Influenza Vaccine Development and Production
11. Occupational exposures may be linked to death from autoimmune disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... Love Digits LLC has successfully launched its ... App brings ancient astrology to the modern dating scene, ... using a five-star rating system. By entering their birth ... their compatibility for love and marriage across seven different ... rating system generates a weighted average of the seven ...
(Date:7/14/2014)... WA (PRWEB) July 14, 2014 ... solutions, today announced its new IBM i (AS/400, ... Software Vendors (ISVs). As security threats evolve and ... software providers struggle to modernize their applications and ... program now makes it easy for ISVs on ...
(Date:7/13/2014)... Florida (PRWEB) July 14, 2014 Save the ... Wolfson Children’s Hospital in Jacksonville, FL , BOXWOODS & BowTies ... 5-7, 2014 , Who: The Women’s Board of Wolfson ... & Antiques Show to continue their ongoing commitment to ... the region’s children. , What: The 2014 Art & ...
(Date:7/13/2014)... TopDresses100.com, a popular dress company in the global market, ... dresses to its product line. According to the ... guaranteed to be quality made. Now, they are offered ... has a wide variety of elegant dresses for customers ... stock and ready to ship. As an innovation-based supplier, ...
(Date:7/13/2014)... July 14, 2014 Recently, iFitDress.com, one ... has released its beautiful collection of brown evening ... outfits are now available at discounted prices, up to ... are of high quality; they are carefully made according ... special occasion gowns, iFitDress.com also offers pretty accessories: wedding ...
Breaking Medicine News(10 mins):Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 2Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 3Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 3Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 4Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 5Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 6Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 7Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 8Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 9Health News:Cheap Multi-colored Quinceanera Dresses From TopDresses100.com 2Health News:2014 Brown Evening Dresses Added To iFitDress.com 2
... Latex Ltd., will be launched next week commercially in select ... 30,000 pieces of female condoms across the country and from ... decided it is time to enter the market. This would ... country,' M. Ayyappan, chairman and managing director of the company, ...
... cancer researchers from all over the world are going to ... what exactly their risk of developing a melanoma is. // ... Leeds, England has been awarded a fund of ?7 million. ... the world. All these teams are working on the genetics ...
... identified by the Oregon National Primate Research Center at ... to control stem cells becoming other brain cells.// New ... and brain injury as a result of continued research. ... early stages before birth, which become glial cells in ...
... C.difficile’s genetic code is reported to have been cracked ... enable faster diagnosis and treatment of the ailment which ... the Jewish General Hospital’s Dasval. The strain has caused ... Quebec. The search can now commence for the other ...
... in his new book 'The Failure of Democratic Nation Building: ... says that Democracy should not or cannot be forcibly thrusted ... with an intrinsic need for hierarchical and authoritarian social and ... other hand requires unique conditions before it is accepted by ...
... team from Universite de Montreal have found that ... endocannabinoids by blocking the degradation in the brain ... brain which is responsible for relaxing brain, endocannabinoids ... during exercises and other well-being activities. The level ...
Cached Medicine News:
(Date:7/11/2014)... DIEGO , July 11, 2014 Neurelis, ... Corp. ("Biotie") to end the option held by Biotie ... commence further development of NRL-1 (intranasal diazepam) for pediatric ... Over the past year, Biotie has advanced ... in preparation for the pivotal clinical work required for ...
(Date:7/10/2014)...  The U.S. Department of Health and Human Services ... (UH) Case Medical Center Seidman Cancer Center totaling $4.7 ... improving care for patients with complex cancer. ... a unique model developed at UH to enhance care ... or demonstrated need for high health care utilization.  ...
(Date:7/10/2014)... 10, 2014  RESMED INC. (NYSE: RMD ) ... fiscal year ended June 30, 2014 results on Thursday, July ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
Breaking Medicine Technology:Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2
... ChromaDex® Corp. (OTCBB: CDXC) today announced that the ... exclusive rights to a joint patent application filed ... of inducing UDP-glucuronosyltransferase (UGT) activity using pTeroPure®, ChromaDex®,s ... blueberries and demonstrated to have multiple health benefits. ...
... Abaxis, Inc. (NasdaqGS: ABAX), a medical products company ... Serverson, chief executive officer,  will present at 2011 Morgan ... 2011 at 10:20 a.m. ET at the Grand Hyatt ... markets and sells portable blood analysis systems for use ...
Cached Medicine Technology:ChromaDex®'s Novel Ingredient pTeroPure® to be Studied as Potential Treatment for Fighting Skin Cancers 2ChromaDex®'s Novel Ingredient pTeroPure® to be Studied as Potential Treatment for Fighting Skin Cancers 3Abaxis to Present at 2011 Morgan Stanley Global Healthcare Unplugged Conference 2
The Nevyas Drape Support is the simple and inexpensive way to establish a zone of comfort for your patients during ophthalmic surgery which requires draping over the nose and mouth. Packaged in sets ...
... important standard in busy operating rooms. The unique ... and supports arms and wrists during ophthalmic surgery. ... fluids are collected. The bar also flips up ... transfer on and off the table. The metal ...
... system provides patients with the ability ... to reading. The telescope has ... viewing. The double lens caps ... 4x magnifications. Each flip-up reading ...
The TV-Mag is a 1.9x focusing telescope, used mainly for watching television. It has a large objective lens giving excellent light transmission and a wide field of view....
Medicine Products: