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Manic phase of bipolar disorder benefits from breast cancer medication
Date:9/12/2007

step toward developing new kinds of medications."

Findings from another recent NIMH study strengthen the results. This previous study showed that the risk of developing bipolar disorder is influenced by a variation in a gene called DGKH. The gene makes a PKC-regulating protein known to be active in the biochemical pathway through which standard medications for bipolar disorder exert their effects another sign that PKC is a promising direct target at which to aim new medications for the illness.

Mania isnt just your average mood swing, where any of us might feel upbeat in response to something that happens. Its part of a brain disorder whose behavioral manifestations can severely undermine peoples jobs, relationships, and health, said Zarate. The sooner we can help patients get back on an even keel, the more we can help them avoid major disruptions to their lives and the lives of people around them.


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Contact: Susan Cahill
scahill@mail.nih.gov
301-443-4536
NIH/National Institute of Mental Health
Source:Eurekalert

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