Navigation Links
Manchester leads new international study investigating Inflammatory Bowl Disease
Date:3/5/2013

The University of Manchester is leading a 12 million systems medicine research network to identify better treatments for Inflammatory Bowel Disease like Crohn's Disease.

Professor Werner Mller from the Faculty of Life Sciences is the Scientific Co-ordinator for the network called SysmedIBD. It includes universities and companies from the UK, Germany, the Netherlands, Israel and New Zealand.

The aim of the five-year project is to better understand the disease, to identify risk genes, to investigate how diet can affect IBD, to develop new biomarkers and mathematical models that can predict the best treatment for a patient. This research network is based on the systems medicine approach in which individual patient specific details are used to build better mathematical models that in turn will provide the best possible treatment suggestions for the patients.

Professor Mller says: "This systems medicine approach will lead to a better personalized diagnosis and treatment of patients with inflammatory bowel disease. We will be targeting the central pathway of inflammation in the hope that by understanding the signalling processes we can eventually manipulate them."

He continues: "IBD affects every patient differently making it very difficult to develop effective treatments. Current treatments are very expensive and many patients develop resistance to the drugs. We hope that this intense programme of research will help us to overcome the current limitations of treatments for this incurable condition."

The term IBD is used mainly to describe two diseases, Crohn's disease and ulcerative colitis. Both Crohn's disease and ulcerative colitis are chronic long-term diseases that involve inflammation of the gastrointestinal.

In the UK, IBD affects about one person in every 350. Around 100,000 people have ulcerative colitis, and 52,000 people have Crohn's disease in England.

Prof Jonathan Rhodes from the collaborating group at the University of Liverpool says "This is a great boost for Inflammatory Bowel Disease research in the UK and stands an excellent chance of leading to benefits for patients".

The scientists taking part in SysMedIBD have been meeting in Manchester to discuss the project. During the discussions they heard from the patient group Crohn's & Colitis UK about what those affected by IBD would like to see come from the work of SysMedIBD.

Professor Mller says: "We hope our findings for Inflammatory Bowel Disease will also increase our understanding of other inflammatory conditions such as arthritis."


'/>"/>

Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

Related medicine news :

1. Premium Astrology Client Care Team Leads Norah Guide to New Reviews Daily
2. Inhaled betadine leads to rare complication
3. Platypus Australia Leads The Way For Summer Fashion By Launching New Range of Children’s UV Protective Swimwear
4. Frog-in-bucket-of-milk folklore leads to potential new antibiotics
5. University of Cincinnati leads first trial on steroid and CNI withdrawal post-transplant
6. Decreased kidney function leads to decreased cognitive functioning
7. Childhood abuse leads to poor adult health
8. Healthy outlook leads to a healthy lifestyle: study
9. Lack of oxygen in cancer cells leads to growth and metastasis
10. Hopkins scientists discover how an out-of-tune protein leads to muscle demise in heart failure
11. Feeding microbials to chickens leads to mysterious immune response
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... April 29, 2016 , ... ... Council for Graduate Medical Education (ACGME) that it has received accreditation for its ... accreditation of three residency programs that Memorial is currently pursuing, including Pediatrics and ...
(Date:4/29/2016)... ... April 29, 2016 , ... On Tuesday, April 26, 2016 members of the ... signature of Gov. Nathan Deal on SB 258, the “Rural Health Care Relief” Bill. ... a 70% tax credit to individuals and corporations which donate directly to a “rural ...
(Date:4/29/2016)... ... April 29, 2016 , ... The White House announced efforts ... more information about their loan terms and accounts, and more protections for borrowers. ... federal and private loans, has reached $1.3 trillion, with 43 million Americans holding ...
(Date:4/29/2016)... Petersburg, Fla. (PRWEB) , ... April 29, 2016 ... ... Children’s Hospital surgeon reveals that infants born with severe congenital diaphragmatic hernia have ... babies is born with congenital diaphragmatic hernia (CDH)—a condition where the diaphragm fails ...
(Date:4/29/2016)... ... 29, 2016 , ... Mobility Designed is redefining mobility with their patent ... M+D Crutch evenly distributes body weight from the elbow to the forearm. In ... crutches than with other crutches. , Co-founders Max and Liliana Younger were inspired to ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... , April 27, 2016 ... accelerator (MR-linac) platform will be the focal point of ... of the European Society for Radiotherapy & Oncology, taking ... MR-linac integrates a state-of-the-art radiotherapy system and a high-field ... to clearly see the patient,s anatomy in real time. ...
(Date:4/27/2016)... 2016 Tie-up with Government hospitals ... to save newborns   Fortis La Femme, ... in collaboration with Breast Milk Foundation (BMF), a non-profit organization ... Milk Bank, ,Amaara, in Delhi-NCR today. This non-profit centre recognizes ... infants and should be available to babies deprived of mother,s ...
(Date:4/27/2016)... Research and Markets has ... Disposables Market 2016-2020"  report to their offering.  ... global anesthesia disposables market is set to ... the period 2016-2020.  Healthcare-acquired infections ... safety. Organizations like the CDC and Public ...
Breaking Medicine Technology: