Navigation Links
Managing Blood Pressure, Cholesterol Cuts Stroke Risk
Date:4/30/2009

Study shows reaching optimal levels protects against heart attack, too

THURSDAY, April 30 (HealthDay News) -- People who have suffered a stroke can significantly reduce the odds of a second stroke or a heart attack by controlling their blood pressure and cholesterol, new research shows.

"There are about 800,000 new strokes in the U.S. and 1 million in Europe each year," said study author Dr. Pierre Amarenco, of Denis Diderot University and Medical School in Paris. "Among them, between 5 and 10 percent will have a recurrent stroke and about 2 percent will have a myocardial infarction."

For the study, researchers followed 4,731 people who had suffered a stroke or "mini-stroke." Half of the patients received the cholesterol-lowering drug atorvastatin (Lipitor), while half received a placebo. Pfizer Inc., which makes Lipitor, funded the study.

The researchers found that over an average of 4.9 years, patients who maintained optimal levels of LDL ("bad") cholesterol, HDL ("good") cholesterol, triglycerides and blood pressure were significantly less likely to suffer a secondary stroke or other cardiovascular problems. The findings were presented Wednesday at the American Academy of Neurology's annual meeting in Seattle.

"In this study, we show that lowering LDL cholesterol is important to reduce the burden of new stroke and myocardial infarction," Amarenco said. "When all four targets were achieved in the SPARCL [Stroke Prevention by Aggressive Reduction in Cholesterol Levels] trial, there was a 75 percent reduction in stroke, myocardial infarction and vascular death."

Despite the promising results, many physicians are concerned about the possible ramifications, both physical and societal, resulting from long-term statin use.

"There is a great worry by all of us that there could be long-term adverse effects from high-dose statins that has not yet been seen," said Dr. Matthew Fink, chief of the division of stroke and critical care neurology at Weill Cornell Medical College in New York City, who adds that HDL levels can be increased naturally through exercise.

For the time being, most researchers agree that it's important to closely monitor patients taking statins.

"Does in-practice therapeutic education of patients with stroke and close monitoring by prevention nurses [nurse practitioners] help patients implement guidelines and make sure they achieve targets to reduce their risk close to the 75 percent we have observed?" asked Amarenco. "The polypill concept is a dream, but therapeutic education and monitoring by nurse practitioners is achievable."

Even if statins prove to be safe when used over the long-term, questions remain about their relatively high cost for much of the world's population.

"What about cost benefit?" Fink asked. "These are expensive drugs, and what happens around the world where people simply can't pay for them?"

More information

Visit the National Institutes of Health for more information on stroke.



SOURCES: Pierre Amarenco, M.D., Denis Diderot University and Medical School, Paris, and fellow, American Academy of Neurology; Matthew Fink, M.D., chief, division of stroke and critical care neurology, Weill Cornell Medical College, New York City; April 29, 2009, presentation, American Academy of Neurology annual meeting, Seattle


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oncologists are critical in managing psychiatric disorders in patients with advanced cancer
2. Methadone and systematic follow-up: the best solution for managing chronic pain
3. Roy Jakobs Appointed Elsevier Managing Director, A&G Sales and Customer Marketing
4. Empowerment Program Gets Patients on the PATH to Managing the Physical and Emotional Effects of Psoriatic Arthritis
5. Call Center Excellence: Managing Service-To-Sales Cultural Transformation
6. XRoads Solutions Group Appoints Dr. Ogan Gurel as Managing Director
7. Casey Family Programs Hires Ken Patterson as Managing Director of Child and Family Services
8. Managing the Service-to-Sales Cultural Transformation - Complimentary Excerpt Available from Best Practices
9. American College of Gastroenterology Offers Updated Clinical Guidance for Managing Pregnant Patients
10. National Nature Made(R) Survey Finds U.S. Adults Are Concerned About Heart Disease but May not be Managing Their Risk
11. Genstar Capital Appoints Mark Hanson to Managing Director
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Managing Blood Pressure, Cholesterol Cuts Stroke Risk
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... "FCPX editors ... customizable inside of Final Cut Pro X," said Christina Austin - CEO of Pixel ... style. Final Cut Pro X users can now reveal the media of ...
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... ... On June 10-11, 2016, A Forever Recovery, a holistic treatment center for ... Table in Battle Creek, MI, where the rehabilitation facility is located. This annual celebration ... world’s leading providers of cereal and other breakfast foods. Its residents often refer to ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal ... personalized through a fitness app. The fitness app plans to fix the two major problems ... offer a one size fits all type program , They don’t eliminate all ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Dialysis Devices Global Market - Forecast to 2022" report ... is the treatment method for the patients with kidney failure, ... and excess fluid from the patient,s blood and thus the ... sodium, potassium and chloride in balance. Increasing ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic ... Coating, Parenteral) - Global Forecast to 2021" report ... The global pharmaceutical excipients market is projected to ... of 6.1% in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: