Navigation Links
Managing Blood Pressure, Cholesterol Cuts Stroke Risk
Date:4/30/2009

Study shows reaching optimal levels protects against heart attack, too

THURSDAY, April 30 (HealthDay News) -- People who have suffered a stroke can significantly reduce the odds of a second stroke or a heart attack by controlling their blood pressure and cholesterol, new research shows.

"There are about 800,000 new strokes in the U.S. and 1 million in Europe each year," said study author Dr. Pierre Amarenco, of Denis Diderot University and Medical School in Paris. "Among them, between 5 and 10 percent will have a recurrent stroke and about 2 percent will have a myocardial infarction."

For the study, researchers followed 4,731 people who had suffered a stroke or "mini-stroke." Half of the patients received the cholesterol-lowering drug atorvastatin (Lipitor), while half received a placebo. Pfizer Inc., which makes Lipitor, funded the study.

The researchers found that over an average of 4.9 years, patients who maintained optimal levels of LDL ("bad") cholesterol, HDL ("good") cholesterol, triglycerides and blood pressure were significantly less likely to suffer a secondary stroke or other cardiovascular problems. The findings were presented Wednesday at the American Academy of Neurology's annual meeting in Seattle.

"In this study, we show that lowering LDL cholesterol is important to reduce the burden of new stroke and myocardial infarction," Amarenco said. "When all four targets were achieved in the SPARCL [Stroke Prevention by Aggressive Reduction in Cholesterol Levels] trial, there was a 75 percent reduction in stroke, myocardial infarction and vascular death."

Despite the promising results, many physicians are concerned about the possible ramifications, both physical and societal, resulting from long-term statin use.

"There is a great worry by all of us that there could be long-term adverse effects from high-dose statins that has not yet been seen," said Dr. Matthew Fink, chief of the division of stroke and critical care neurology at Weill Cornell Medical College in New York City, who adds that HDL levels can be increased naturally through exercise.

For the time being, most researchers agree that it's important to closely monitor patients taking statins.

"Does in-practice therapeutic education of patients with stroke and close monitoring by prevention nurses [nurse practitioners] help patients implement guidelines and make sure they achieve targets to reduce their risk close to the 75 percent we have observed?" asked Amarenco. "The polypill concept is a dream, but therapeutic education and monitoring by nurse practitioners is achievable."

Even if statins prove to be safe when used over the long-term, questions remain about their relatively high cost for much of the world's population.

"What about cost benefit?" Fink asked. "These are expensive drugs, and what happens around the world where people simply can't pay for them?"

More information

Visit the National Institutes of Health for more information on stroke.



SOURCES: Pierre Amarenco, M.D., Denis Diderot University and Medical School, Paris, and fellow, American Academy of Neurology; Matthew Fink, M.D., chief, division of stroke and critical care neurology, Weill Cornell Medical College, New York City; April 29, 2009, presentation, American Academy of Neurology annual meeting, Seattle


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oncologists are critical in managing psychiatric disorders in patients with advanced cancer
2. Methadone and systematic follow-up: the best solution for managing chronic pain
3. Roy Jakobs Appointed Elsevier Managing Director, A&G Sales and Customer Marketing
4. Empowerment Program Gets Patients on the PATH to Managing the Physical and Emotional Effects of Psoriatic Arthritis
5. Call Center Excellence: Managing Service-To-Sales Cultural Transformation
6. XRoads Solutions Group Appoints Dr. Ogan Gurel as Managing Director
7. Casey Family Programs Hires Ken Patterson as Managing Director of Child and Family Services
8. Managing the Service-to-Sales Cultural Transformation - Complimentary Excerpt Available from Best Practices
9. American College of Gastroenterology Offers Updated Clinical Guidance for Managing Pregnant Patients
10. National Nature Made(R) Survey Finds U.S. Adults Are Concerned About Heart Disease but May not be Managing Their Risk
11. Genstar Capital Appoints Mark Hanson to Managing Director
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Managing Blood Pressure, Cholesterol Cuts Stroke Risk
(Date:4/29/2017)... (PRWEB) , ... April 29, 2017 , ... ... Grocery Company to the list of fine retailers selling biodegradable, hanging flushable wipes ... H.E.B., a large supermarket chain headquartered in San Antonio, Texas, operates more than ...
(Date:4/28/2017)... ... April 28, 2017 , ... Accreditation Commission for Health Care ... of America (HCAOA). This agreement allows HCAOA members to receive special pricing on ... on Accreditation University (AU) educational resources that help prepare HCAOA members for ACHC ...
(Date:4/28/2017)... ... April 28, 2017 , ... Getting enough sleep affects much more than energy – ... just 19 hours without sleep can compromise motor reaction time, which can increase the risk ... Insurance is sharing the following tips from the NSF to help you sleep better and ...
(Date:4/28/2017)... ... April 28, 2017 , ... Datta Endoscopic Back ... joined the revolutionary endoscopic practice under Dr. Datta. Patel is a Board Certified ... The patented, revolutionary eDiscSculpt Technique created and used by Datta Endoscopic is unlike ...
(Date:4/28/2017)... MA (PRWEB) , ... April 28, 2017 , ... People ... for older people. “Wearing a hearing aid doesn’t have the stigma it had when ... & Hearing Associates of Greater Boston, in a NALA North American Speaker Series ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... DIEGO , April 19, 2017  Sorrento ... an antibody-centric, clinical-stage biopharmaceutical company developing new treatments ... announced the closing of its previously announced underwritten ... stock at a public offering price of $2.00 ... and estimated offering expenses payable by Sorrento.  The ...
(Date:4/19/2017)... 19, 2017  Novartis today announced the publication ... Lung, and Blood Institute (NHLBI) of the National ... patients with treatment-naïve severe aplastic anemia (SAA) achieved ... eltrombopag at the initiation of and concurrently with ... three sequential treatment groups, or cohorts. Cohort 3 ...
(Date:4/18/2017)... 18, 2017 Cogentix Medical, Inc. (NASDAQ: CGNT), ... Urology, Uro/Gyn and Gynecology markets with innovative and proprietary ... ended March 31, 2017 after the market close on ... will host a conference call and webcast to discuss ... 2, 2017 at 4:30 p.m. Eastern Time (3:30 p.m. ...
Breaking Medicine Technology: