Navigation Links
Managing Blood Pressure, Cholesterol Cuts Stroke Risk
Date:4/30/2009

Study shows reaching optimal levels protects against heart attack, too

THURSDAY, April 30 (HealthDay News) -- People who have suffered a stroke can significantly reduce the odds of a second stroke or a heart attack by controlling their blood pressure and cholesterol, new research shows.

"There are about 800,000 new strokes in the U.S. and 1 million in Europe each year," said study author Dr. Pierre Amarenco, of Denis Diderot University and Medical School in Paris. "Among them, between 5 and 10 percent will have a recurrent stroke and about 2 percent will have a myocardial infarction."

For the study, researchers followed 4,731 people who had suffered a stroke or "mini-stroke." Half of the patients received the cholesterol-lowering drug atorvastatin (Lipitor), while half received a placebo. Pfizer Inc., which makes Lipitor, funded the study.

The researchers found that over an average of 4.9 years, patients who maintained optimal levels of LDL ("bad") cholesterol, HDL ("good") cholesterol, triglycerides and blood pressure were significantly less likely to suffer a secondary stroke or other cardiovascular problems. The findings were presented Wednesday at the American Academy of Neurology's annual meeting in Seattle.

"In this study, we show that lowering LDL cholesterol is important to reduce the burden of new stroke and myocardial infarction," Amarenco said. "When all four targets were achieved in the SPARCL [Stroke Prevention by Aggressive Reduction in Cholesterol Levels] trial, there was a 75 percent reduction in stroke, myocardial infarction and vascular death."

Despite the promising results, many physicians are concerned about the possible ramifications, both physical and societal, resulting from long-term statin use.

"There is a great worry by all of us that there could be long-term adverse effects from high-dose statins that has not yet been seen," said Dr. Matthew Fink, chief of the division of stroke and critical care neurology at Weill Cornell Medical College in New York City, who adds that HDL levels can be increased naturally through exercise.

For the time being, most researchers agree that it's important to closely monitor patients taking statins.

"Does in-practice therapeutic education of patients with stroke and close monitoring by prevention nurses [nurse practitioners] help patients implement guidelines and make sure they achieve targets to reduce their risk close to the 75 percent we have observed?" asked Amarenco. "The polypill concept is a dream, but therapeutic education and monitoring by nurse practitioners is achievable."

Even if statins prove to be safe when used over the long-term, questions remain about their relatively high cost for much of the world's population.

"What about cost benefit?" Fink asked. "These are expensive drugs, and what happens around the world where people simply can't pay for them?"

More information

Visit the National Institutes of Health for more information on stroke.



SOURCES: Pierre Amarenco, M.D., Denis Diderot University and Medical School, Paris, and fellow, American Academy of Neurology; Matthew Fink, M.D., chief, division of stroke and critical care neurology, Weill Cornell Medical College, New York City; April 29, 2009, presentation, American Academy of Neurology annual meeting, Seattle


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oncologists are critical in managing psychiatric disorders in patients with advanced cancer
2. Methadone and systematic follow-up: the best solution for managing chronic pain
3. Roy Jakobs Appointed Elsevier Managing Director, A&G Sales and Customer Marketing
4. Empowerment Program Gets Patients on the PATH to Managing the Physical and Emotional Effects of Psoriatic Arthritis
5. Call Center Excellence: Managing Service-To-Sales Cultural Transformation
6. XRoads Solutions Group Appoints Dr. Ogan Gurel as Managing Director
7. Casey Family Programs Hires Ken Patterson as Managing Director of Child and Family Services
8. Managing the Service-to-Sales Cultural Transformation - Complimentary Excerpt Available from Best Practices
9. American College of Gastroenterology Offers Updated Clinical Guidance for Managing Pregnant Patients
10. National Nature Made(R) Survey Finds U.S. Adults Are Concerned About Heart Disease but May not be Managing Their Risk
11. Genstar Capital Appoints Mark Hanson to Managing Director
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Managing Blood Pressure, Cholesterol Cuts Stroke Risk
(Date:4/29/2016)... Sterling, VA (PRWEB) , ... April 29, 2016 ... ... Americans with student loans more flexibility in repaying their loans, more information about ... at a time when total outstanding student loan debt, including federal and private ...
(Date:4/29/2016)... ... April 29, 2016 , ... A ... born with severe congenital diaphragmatic hernia have better survival rates if surgery is ... hernia (CDH)—a condition where the diaphragm fails to form completely, letting abdominal organs ...
(Date:4/29/2016)... ... ... Mobility Designed is redefining mobility with their patent pending crutch design. ... distributes body weight from the elbow to the forearm. In consumer tests, users ... other crutches. , Co-founders Max and Liliana Younger were inspired to design the crutches ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... Melanoma is the deadliest type of skin ... blame for the majority of skin cancer deaths. More than 10,000 people are expected to ... at diagnosis is 62, it is the one of the most commonly diagnosed cancers in ...
(Date:4/29/2016)... Hills, CA (PRWEB) , ... April 29, 2016 , ... ... of devices and products for the head and neck/ear, nose and throat specialty, has ... Device , The KOTLER NASAL AIRWAY™ is a newly patented safety device ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... YORK , April 28, 2016  While ... notably complement the company,s valve repair and stent ... move also places Abbott more firmly into patient ... of the fastest growing device areas, with double-digit ... its recent report,  Advanced Remote Patient Monitoring ...
(Date:4/28/2016)... YORK , April 28, 2016  The blood ... 275 million dollars, according to Kalorama Information and The ... typing, immunoassays and nucleic acid testing.  The healthcare research ... made progress in developing blood collection stations and in ... made in Kalorama Information,s report, Blood Testing ...
(Date:4/28/2016)... , April 28, 2016 Oramed ... a clinical-stage pharmaceutical company focused on the development of oral ... in the upcoming PIONEERS 2016 conference, presented by Joseph ... 2016 in New York . Nadav ... at the conference. Presentation Details:   ...
Breaking Medicine Technology: