Navigation Links
Mammography plus sonography can help rule out breast cancer in patients with palpable lesions
Date:4/11/2008

When mammography and sonography are used together to evaluate palpable breast lesions, they can rule out cancers in most patients, according to a recent study conducted by researchers at Baystate Health in Springfield, MA. However, uncommonly, malignancies cannot be diagnosed using this imaging protocol.

We were interested in finding out just how effective mammography and sonography were, when used together, in excluding breast cancer in women with palpable findings, said Erica Tyler, MD, lead author of the study. Our study differs from others because after enrollment, we followed patients for at least 3 years to see if any of the palpable lumps later were diagnosed as malignant, she said.

The study evaluated 414 palpable breast lesions using both mammography and sonography. Imaging of 167 lesions was negative, with normal appearing breast tissue in the area of clinical concern and no mammographic or sonographic findings to explain the palpable finding. Among the 167 women with negative mammography and sonography, 120 reached a diagnostic endpoint with 28 patients undergoing a biopsy that showed no malignancy and 92 patients showing no malignancy after follow-up of at least 36 months. There were 118 true-negative and two false-negative cases said Dr. Tyler. The NPV when using mammography and sonography together was 98%, she said.

The study showed that both false-negative lesions became increasingly suspicious on clinical exam and later became apparent by imaging, said Dr. Tyler. One false-negative lesion occurred in a patient with heterogeneously dense tissue and was diagnosed 74 months after initial clinical discovery. The second false-negative lesion occurred in extremely dense tissue and was diagnosed 81 months after initial discovery.

Our findings support those reported in other studies. Uncommonly, palpable malignancies may not be detectable on both mammography and sonography, and this combination of imaging doesnt rule out malignancy, said Dr. Tyler. Also, based on our findings, long term clinical and imaging follow-up of over five years may be needed to diagnose all palpable cancers, when the initial mammogram and sonogram are unrevealing, she said.


'/>"/>

Contact: Necoya Tyson
necoya@arrs.org
703-858-4304
American Roentgen Ray Society
Source:Eurekalert

Related medicine news :

1. Screening mammography in elderly patients beneficial
2. iCAD Receives FDA Approval for Its SecondLook Digital for Use With Fujis Digital Mammography System
3. Computer-Aided Detection in Screening Mammography Enhances Performance of a Single Reader
4. Pennsylvania DEP Releases 4th Quarter 2007 Mammography Inspection Results
5. iCAD Ranks #1 in Mammography CAD User Satisfaction
6. Digital Mammography Better Than Film for Some Women
7. Digital mammography superior to film mammography in some cases
8. Health insurance co-payments deter mammography use
9. Cone-Beam CT faster, potentially more accurate than conventional mammography
10. Breast Cancer Imaging Study Indicates Breast-Specific Gamma Imaging (BSGI) Is a Strong Adjunct Imaging Modality to Mammography and Ultrasound
11. Stereo mammography takes breast imaging to a new dimension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... ... June 28, 2017 , ... Continually at the forefront of ... Drops™ have received the Non-GMO Project Verified seal. All five flavors of the ... only third-party verification for non-GMO foods and products in North America. , Available ...
(Date:6/28/2017)... Pekin, IL (PRWEB) , ... June 28, 2017 , ... ... research shows that every 62 minutes, at least one person dies as a direct ... grows, a greater need exists for qualified treatment providers. The iaedp Foundation meets this ...
(Date:6/28/2017)... ... June 28, 2017 , ... Canadian Zeolite Corp. (the “Company”) ... year study conducted by the University of Saskatchewan in partnership with PotashCorp, Agrium ... brine-impacted groundwater. As a part of the study, batch adsorption experiments were conducted ...
(Date:6/27/2017)... Fla. (PRWEB) , ... June 27, 2017 , ... ... today announced the appointment of Mike Finnegan to the position of Executive Vice ... years of experience in healthcare technology, telehealth and medical device sales leadership. He ...
(Date:6/27/2017)... ... 27, 2017 , ... The Congressional Budget Office (CBO) projects that the Better ... Patient Protection and Affordable Care Act (ACA), would result in 22 million Americans losing ... law. , More than 20 million Americans have gained health insurance under the ACA, ...
Breaking Medicine News(10 mins):
(Date:6/13/2017)... 2017 Zimmer Biomet Holdings, Inc. (NYSE and SIX: ... the U.S. Food and Drug Administration (FDA) has notified the ... to its Zhejiang, China manufacturing facility ... "The successful clearance of the Warning Letter related to our ... a measure of the progress we have made in our ...
(Date:6/11/2017)...  Eli Lilly and Company (NYSE: LLY ) ... of galcanezumab, an investigational treatment for the prevention of ... key secondary endpoints for galcanezumab compared to placebo at ... EVOLVE-2 and REGAIN) will be presented today at the ... Boston . "The detailed ...
(Date:6/9/2017)... Calif. , June 9, 2017 AirXpanders, ... company focused on the design, manufacture, sale and distribution ... market on the progress of its commercial roll-out in ... now available in more than one hundred (100) medical ... AeroForm offers a needle-free alternative for women ...
Breaking Medicine Technology: