Navigation Links
Mammary gland development of blueberry-fed lab animals studied
Date:6/7/2011

This release is available in Spanish.

U.S. Department of Agriculture (USDA)-funded studies of mammary gland development in laboratory rats fed blueberries or other foods of interest may aid breast cancer research.

In an early study that has paved the way to follow-up experiments, Rosalia C. M. Simmen of the Arkansas Children's Nutrition Center (ACNC) in Little Rock, Ark., has determined that several indicators of rat mammary gland health were improved in the offspring (pups) of mothers (dams) that had been fed 5 percent blueberry powder in their rations during pregnancy and during the weeks that they nursed their pups.

The powder comprised 5 percent of the total weight of the feed, according to Simmen, a senior investigator at the center and a professor at the University of Arkansas for Medical Sciences in Little Rock.

The ACNC is a partnership between the USDA's Agricultural Research Service (ARS), Arkansas Children's Hospital in Little Rock, and the university.

The effects noted in the blueberry study have not been shown in humans and have not yet been traced to a particular blueberry compound, Simmen noted.

Her team evaluated several structural indicators of normal mammary gland development in the lab animals, including branching of the gland. There was significantly more branching in the offspring of the group that consumed the diet containing 5 percent blueberry powder than in offspring of dams fed rations containing 2.5 percent or 10 percent blueberry powder, Simmen reported.

Branching occurs when cells specialize or differentiate. Differentiation is generally preferable to rapid proliferation of undifferentiated cells, which can be a risk factor for breast cancer.

In their analysis of several biochemical indicators, the team found, for instance, that the level of the tumor-suppressing protein PTEN (phosphatase and tensin homolog deleted in chromosome 10) was significantly higher in mammary tissues of offspring of dams on the 5 percent regimen. That's a plus, because PTEN is thought to help protect against cancer.

Lab animal studies of blueberries' potential role in preventing breast cancer date to 2006. But Simmen's investigation, published in Nutrition Research in 2009, provided the first evidence from a lab animal study of the early influence that the mother's blueberry consumption can have on normal, healthy development of the mammary gland in her offspring.


'/>"/>

Contact: Marcia Wood
marcia.wood@ars.usda.gov
301-504-1662
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

Related medicine news :

1. MicroRNA controls mammary gland development in mice
2. For the first time, researchers identify and isolate adult mammary stem cells in mice
3. Americans have higher rates of most chronic diseases than same-age counterparts in England
4. Salivary glands as organs of immunity: New research makes oral immunization easier to swallow
5. Genetic Research Sheds Light on Adrenal Gland Tumor Risk
6. Researchers discover important link between adrenal gland hormone and brain in hypertension
7. MISI Company, Ltd. Acquires Cue Data Services and Expands Geographically to New England and Canada
8. Cancers of sweat glands, other skin-related structures may be increasing in United States
9. Health New England Selects Panviva to Support Growth Initiatives
10. Alcohol-related death rates much higher in deprived areas of England and Wales
11. Business Customers in New England Receive the Latest Internet Telephone Service Upgrade
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... ... Remember the old saying “rub some dirt on it”? Perhaps you should try ... Clay” the health benefits of integrating clay into a daily diet are numerous, as ... motivational speaker, Perry A~ has since dedicated her life to learning about the benefits ...
(Date:2/8/2016)... , ... February 08, 2016 , ... ... wide variety of organizations. DocuSyst provides a cloud hosted environment for FileHold ... installations include integration with various 3rd party applications using the FileHold web services ...
(Date:2/8/2016)... ... 2016 , ... GrassrootsHealth published data from its D*action public ... in the GrassrootsHealth cohort with substantially higher vitamin D levels than a cohort ... states Carole Baggerly, Director of GrassrootsHealth, “the safety and benefits of vitamin ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... TopConsumerReviews.com recently ... in Mole removal products. , Moles are derived from a cluster of melanin when ... all the wrong places and create a lifetime of embarrassment. Historically, mole removal ...
(Date:2/8/2016)... ... , ... Guruji Mahendra Kumar Trivedi is offering 3 days of accelerated personal ... birthday on February 10th. During this time, people can achieve better health, greater ... people from over 40 different countries as an “ordinary man with an extraordinary gift.” ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Feb. 8, 2016  Unilife Corporation ("Unilife" or "Company") (NASDAQ: ... injectable drug delivery systems, today announced that it will release ... December 31, 2015 after market close on February 9, 2016. ... call to discuss these financial results.    About ... --> About Unilife Corporation ...
(Date:2/8/2016)... NORTHBROOK, Ill. , Feb. 8, 2016  Astellas Pharma ... today announced the promotion of James Robinson as ... the company,s operations in North and South America ... president, Astellas Pharma US, representing the commercial organization in ... assumed in 2013. Masao Yoshida , who ...
(Date:2/8/2016)... Palatin Technologies, Inc. (NYSE MKT: PTN), ... for the treatment of diseases with significant unmet ... the United States Patent and Trademark Office (USPTO) ... Patent Application Serial Number 14/313,258 (the ,258 application).  ... female sexual dysfunction using the formulation and dose ...
Breaking Medicine Technology: