Navigation Links
Mammary gland development of blueberry-fed lab animals studied
Date:6/7/2011

This release is available in Spanish.

U.S. Department of Agriculture (USDA)-funded studies of mammary gland development in laboratory rats fed blueberries or other foods of interest may aid breast cancer research.

In an early study that has paved the way to follow-up experiments, Rosalia C. M. Simmen of the Arkansas Children's Nutrition Center (ACNC) in Little Rock, Ark., has determined that several indicators of rat mammary gland health were improved in the offspring (pups) of mothers (dams) that had been fed 5 percent blueberry powder in their rations during pregnancy and during the weeks that they nursed their pups.

The powder comprised 5 percent of the total weight of the feed, according to Simmen, a senior investigator at the center and a professor at the University of Arkansas for Medical Sciences in Little Rock.

The ACNC is a partnership between the USDA's Agricultural Research Service (ARS), Arkansas Children's Hospital in Little Rock, and the university.

The effects noted in the blueberry study have not been shown in humans and have not yet been traced to a particular blueberry compound, Simmen noted.

Her team evaluated several structural indicators of normal mammary gland development in the lab animals, including branching of the gland. There was significantly more branching in the offspring of the group that consumed the diet containing 5 percent blueberry powder than in offspring of dams fed rations containing 2.5 percent or 10 percent blueberry powder, Simmen reported.

Branching occurs when cells specialize or differentiate. Differentiation is generally preferable to rapid proliferation of undifferentiated cells, which can be a risk factor for breast cancer.

In their analysis of several biochemical indicators, the team found, for instance, that the level of the tumor-suppressing protein PTEN (phosphatase and tensin homolog deleted in chromosome 10) was significantly higher in mammary tissues of offspring of dams on the 5 percent regimen. That's a plus, because PTEN is thought to help protect against cancer.

Lab animal studies of blueberries' potential role in preventing breast cancer date to 2006. But Simmen's investigation, published in Nutrition Research in 2009, provided the first evidence from a lab animal study of the early influence that the mother's blueberry consumption can have on normal, healthy development of the mammary gland in her offspring.


'/>"/>

Contact: Marcia Wood
marcia.wood@ars.usda.gov
301-504-1662
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

Related medicine news :

1. MicroRNA controls mammary gland development in mice
2. For the first time, researchers identify and isolate adult mammary stem cells in mice
3. Americans have higher rates of most chronic diseases than same-age counterparts in England
4. Salivary glands as organs of immunity: New research makes oral immunization easier to swallow
5. Genetic Research Sheds Light on Adrenal Gland Tumor Risk
6. Researchers discover important link between adrenal gland hormone and brain in hypertension
7. MISI Company, Ltd. Acquires Cue Data Services and Expands Geographically to New England and Canada
8. Cancers of sweat glands, other skin-related structures may be increasing in United States
9. Health New England Selects Panviva to Support Growth Initiatives
10. Alcohol-related death rates much higher in deprived areas of England and Wales
11. Business Customers in New England Receive the Latest Internet Telephone Service Upgrade
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... 2017 , ... Occupational pesticide exposure is linked to an ... according to a study released today at the 1st Pan American Parkinson’s and ... pesticides and incidence of sporadic PD through occupational exposure. This latest study, led ...
(Date:2/24/2017)... ... February 24, 2017 , ... ... replacement options at his office, Antoine Dental Center. Currently, patients can get single ... restrictions may apply, but patients can learn more about these offers by contacting ...
(Date:2/24/2017)... , ... February 24, 2017 , ... An in-depth computational ... the University of Pittsburgh points to eight genes that may explain why susceptibility to ... to the results of a study published today in the journal npj Schizophrenia. ...
(Date:2/24/2017)... ... , ... In the Health Care IT campaign, Robert Herjavec discusses health IT ... you will be attacked, but when.” However, he and many others involved highlight a ... Improvements in auditing and monitoring have taken security in health care a very long ...
(Date:2/24/2017)... ... , ... The narrative in “ Signal 8: An Australian Paramedic’s Story ” ... paramedic experiences. Schanssema describes the tragedies he saw, as well as his struggles with ... Schanssema, initially unsure of the career path he wanted to take, found fulfillment in ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... , Südkorea, 23. Februar 2017 LG Innotek ... Sterilisationsaufgaben vorgestellt. Die Sterilisationsleistung beträgt das 1,5-fache des 45-mW-Moduls ... Strahlung im Bereich zwischen 200 und 280 nm und eignet ... Bakterien, indem es ihre DNA zerstört. Das Produkt von ... ...
(Date:2/23/2017)... Feb. 23, 2017 ITL Limited, ( ASX: ITD ), ... for the half year ended 31 December 2016 compared with the ... presentation can be viewed here . Highlights ... $1.04m; up 104%) Earnings per share of 2.2 ... of $17.5m (Dec 2015: $15.7m; up 11%) Profit ...
(Date:2/23/2017)... 2017 Research and Markets has announced the addition ... report to their offering. ... The latest research Menopause Drugs Price Analysis and Strategies - 2016, provides ... research answers the following questions: What are ... they positioned in the Global Menopause market? What are ...
Breaking Medicine Technology: