Navigation Links
Mammary gland development of blueberry-fed lab animals studied
Date:6/7/2011

This release is available in Spanish.

U.S. Department of Agriculture (USDA)-funded studies of mammary gland development in laboratory rats fed blueberries or other foods of interest may aid breast cancer research.

In an early study that has paved the way to follow-up experiments, Rosalia C. M. Simmen of the Arkansas Children's Nutrition Center (ACNC) in Little Rock, Ark., has determined that several indicators of rat mammary gland health were improved in the offspring (pups) of mothers (dams) that had been fed 5 percent blueberry powder in their rations during pregnancy and during the weeks that they nursed their pups.

The powder comprised 5 percent of the total weight of the feed, according to Simmen, a senior investigator at the center and a professor at the University of Arkansas for Medical Sciences in Little Rock.

The ACNC is a partnership between the USDA's Agricultural Research Service (ARS), Arkansas Children's Hospital in Little Rock, and the university.

The effects noted in the blueberry study have not been shown in humans and have not yet been traced to a particular blueberry compound, Simmen noted.

Her team evaluated several structural indicators of normal mammary gland development in the lab animals, including branching of the gland. There was significantly more branching in the offspring of the group that consumed the diet containing 5 percent blueberry powder than in offspring of dams fed rations containing 2.5 percent or 10 percent blueberry powder, Simmen reported.

Branching occurs when cells specialize or differentiate. Differentiation is generally preferable to rapid proliferation of undifferentiated cells, which can be a risk factor for breast cancer.

In their analysis of several biochemical indicators, the team found, for instance, that the level of the tumor-suppressing protein PTEN (phosphatase and tensin homolog deleted in chromosome 10) was significantly higher in mammary tissues of offspring of dams on the 5 percent regimen. That's a plus, because PTEN is thought to help protect against cancer.

Lab animal studies of blueberries' potential role in preventing breast cancer date to 2006. But Simmen's investigation, published in Nutrition Research in 2009, provided the first evidence from a lab animal study of the early influence that the mother's blueberry consumption can have on normal, healthy development of the mammary gland in her offspring.


'/>"/>

Contact: Marcia Wood
marcia.wood@ars.usda.gov
301-504-1662
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

Related medicine news :

1. MicroRNA controls mammary gland development in mice
2. For the first time, researchers identify and isolate adult mammary stem cells in mice
3. Americans have higher rates of most chronic diseases than same-age counterparts in England
4. Salivary glands as organs of immunity: New research makes oral immunization easier to swallow
5. Genetic Research Sheds Light on Adrenal Gland Tumor Risk
6. Researchers discover important link between adrenal gland hormone and brain in hypertension
7. MISI Company, Ltd. Acquires Cue Data Services and Expands Geographically to New England and Canada
8. Cancers of sweat glands, other skin-related structures may be increasing in United States
9. Health New England Selects Panviva to Support Growth Initiatives
10. Alcohol-related death rates much higher in deprived areas of England and Wales
11. Business Customers in New England Receive the Latest Internet Telephone Service Upgrade
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... Malvern, PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best ... New York City on October 11, 2017. , The annual award competition recognizes editorial ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ® ... fulfilling the promise of precision medicine, today announced that ... Caris, Precision Oncology Alliance™ (POA) as its 17 th ... the St. Jude Crosson Cancer Institute will help develop ... use of tumor profiling, making cancer treatment more precise ...
(Date:10/10/2017)... Oct. 10, 2017  NDS received FDA 510(k) clearance in May ... battery-powered display stand specifically designed for endoscopy environments. An innovative secondary ... a clinical solution to support the improvement of patient outcomes, procedural ... ... ...
(Date:10/5/2017)... , Oct. 5, 2017  In response ... of Oral and Maxillofacial Surgeons (AAOMS) released prescribing ... – to be used as a first-line therapy ... Recognizing the ... AAOMS White Paper "Opioid Prescribing: Acute and Postoperative ...
Breaking Medicine Technology: